BfR – Department 3: Scientific Services (BfR - QUER)
The Department 3 'Scientific Services' assumes a service function for scientific tasks and fulfils cross-sectional tasks within BfR. Main tasks are the evaluation of possible health risks from the transportation of hazardous goods, the biostatistician advisory of BfR units, and to assist quantitative risk evaluations. Furthermore, the development of methods for risk evaluation, the preparation of advisory opinions in epidemiology-statistical studies, and the estimation of exposure and quality management are main objectives. Assessment of Intoxications Exposure Assessment and Exposure Standardisation
Parent institution:
Federal Institute for Risk Assessment (BfR) Details of BfR
Address
BfR – Department 3: Scientific Services (BfR - QUER)
Diedersdorfer Weg 1
12277 Berlin
Berlin
Phone: +49-(0)30-18412-2200
Fax: +49-(0)30-18412-2958
email: 3(@)bfr.bund.de
Activities:
- Research
Focus of Research:
- Biometry, Epidemiology and mathematical modeling and development of quantitative risk models
- Development and application of computer-based evaluation of programs Highthroughput data (eg in the field of proteomics)
- Development of a database on food additives
- Development of models for the food and feed safety to describe the accumulation of contaminants in laboratory animals (eg dioxins)
- Development of models to represent the statistical uncertainties in the estimation of frequency of illness or infection
- Evaluation of the statistical reliability of monitoring strategies
- Exposure of the German population to environmental contaminants (heavy metals, dioxins and PCBs)
- Exposure of the German population to plasticizers by eating food and consumer products
- Exposure to perfluorinated hydrocarbons on food consumption
- Improvements in early detection and documentation of poisoning events in Germany
- Improvements in the use and operation of BfR\'s poison information database with particular issues in the retrieval and data security
- Research on health risks of chemical substances occur primarily in the transport of dangerous goods at sea or in the application (eg, ballast water treatment)
- Scientific preparation for the introduction of a \'Total Diet Study\' in Germany
- Statistical methods for exploration and analysis of goods flows through graph theory network analysis (eg in the EHEC outbreak events)
- Validation of diagnostic tests without a gold standard
Coordinated projects
- Action Programme Environment and Health. Project: Improvement of the /Recording of Human Exposure Data for the Quality Enhancement of the Monitoring System 'Cases of Poisoning Reported by Physicians under Section 16e of the German Chemicals Act Details of Action Programme Environment and Health. Project: Improvement of the /Recording of Human Exposure Data for the Quality Enhancement of the Monitoring System 'Cases of Poisoning Reported by Physicians under Section 16e of the German Chemicals Act
- Characterization of the barrier function of human reconstructed skin models Details of Characterization of the barrier function of human reconstructed skin models
- Cumarine exposition: Cinnamon as ingredient of foodstuffs. Module 1: database children; Module 2: database adolescents/adults Details of Cumarine exposition: Cinnamon as ingredient of foodstuffs. Module 1: database children; Module 2: database adolescents/adults
- Description of the Nature of Accidental Misuse of Chemicals and Chemical Products (DeNaMiC) Details of Description of the Nature of Accidental Misuse of Chemicals and Chemical Products (DeNaMiC)
- Determining the uptake of food additives by children and adolescents in Germany Details of Determining the uptake of food additives by children and adolescents in Germany
- Development of a Technical Guidance Document for preparing the Chemical Safety Report (REACH / RIP 3.2-2) Details of Development of a Technical Guidance Document for preparing the Chemical Safety Report (REACH / RIP 3.2-2)
- Development of an approach to adopt the Langual system for product categorisation purposes with focus on the EU exposure assessment toolbox (CCR.IHCP.C432952.X0) Details of Development of an approach to adopt the Langual system for product categorisation purposes with focus on the EU exposure assessment toolbox (CCR.IHCP.C432952.X0)
- Evaluation of endpoints in addition to MTT for predicting skin irritation potential of chemical substances with in vitro human reconstructed skin models. Details of Evaluation of endpoints in addition to MTT for predicting skin irritation potential of chemical substances with in vitro human reconstructed skin models.
- Evaluation of exposure data on consumer products (ChemTest Phase I) Details of Evaluation of exposure data on consumer products (ChemTest Phase I)
- Foodborne intake of environmental contaminants - Analysis of the National Food Consumption Survey II (NVS II) Details of Foodborne intake of environmental contaminants - Analysis of the National Food Consumption Survey II (NVS II)
- In vitro tests for photogenotoxicity assessment as alternatives to photocarcinogenicity tests in ro-dents (Project part 1). Details of In vitro tests for photogenotoxicity assessment as alternatives to photocarcinogenicity tests in ro-dents (Project part 1).
- Inhalation toxicity of nano-aerosols - animal studies Details of Inhalation toxicity of nano-aerosols - animal studies
- North Sea Ballast Water Opportunity Developing preventative and responsive measures to address acute and chronic marine pollution (Interreg IVB) Details of North Sea Ballast Water Opportunity Developing preventative and responsive measures to address acute and chronic marine pollution (Interreg IVB)
- Phthalate exposure of the population in Germany: relevant exposure sources, intake pathways and toxicokinetics using the example of DEHP (diethylhexylphthalate) Details of Phthalate exposure of the population in Germany: relevant exposure sources, intake pathways and toxicokinetics using the example of DEHP (diethylhexylphthalate)
- Prevalidation for testing the toxic effects of inhaled active substances (gases) after direct exposure of lung cells of people in the Luft-/Flüssigkeitsgrenzschicht Details of Prevalidation for testing the toxic effects of inhaled active substances (gases) after direct exposure of lung cells of people in the Luft-/Flüssigkeitsgrenzschicht
- Project to develop Animal Risk Assessment Guidelines on housing and management (Animal Welfare)(CFP/EFSA/AHAW/2009/01) Work package 2: Hazard identification and characterisation, and exposure assessment Details of Project to develop Animal Risk Assessment Guidelines on housing and management (Animal Welfare)(CFP/EFSA/AHAW/2009/01) Work package 2: Hazard identification and characterisation, and exposure assessment
- Review of consumer exposure data files contained in the 'European Exposure Assessment Toolbox' and introuction of new data from European Chemicals Bureau Risk Assessment Reports currently under development Details of Review of consumer exposure data files contained in the 'European Exposure Assessment Toolbox' and introuction of new data from European Chemicals Bureau Risk Assessment Reports currently under development
- Support to complete EFSA's food consumption concise database (CFP/EFSA/DATEX/2007/01) - SuConDa Details of Support to complete EFSA's food consumption concise database (CFP/EFSA/DATEX/2007/01) - SuConDa
- Validation study for testing of skin penetration using biotechnologically devised human skin equivalents. Phase 2: Validation Details of Validation study for testing of skin penetration using biotechnologically devised human skin equivalents. Phase 2: Validation
Involved in research projects:
- Determination of pyrrolizidin alkaloids in milk and milk products – Carry Over Study Details of Determination of pyrrolizidin alkaloids in milk and milk products – Carry Over Study
- List of chemicals with missing IC 50-values and/or LD 50-values Details of List of chemicals with missing IC 50-values and/or LD 50-values
- New approaches to the study of food security on the basis of cell culture systems: development of a cell culture model to evaluate the influence of dietary factors on gene expression in colon cells by the example of fatty acids Details of New approaches to the study of food security on the basis of cell culture systems: development of a cell culture model to evaluate the influence of dietary factors on gene expression in colon cells by the example of fatty acids
- PERFOOD - Perfluorinated Compounds in our diet Details of PERFOOD - Perfluorinated Compounds in our diet
- Quantification of residues of coccidiostats in feed and food of animal origin caused by carry over from contaminated feed. Details of Quantification of residues of coccidiostats in feed and food of animal origin caused by carry over from contaminated feed.
- Transfer of iodine from teat disinfectants on teat skin and teat canal Details of Transfer of iodine from teat disinfectants on teat skin and teat canal
Work package leader of collaborative projects:
- Interreg IV B North Sea Region Programme Details of Interreg IV B North Sea Region Programme