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Projects of "BMBF - alternative methods to animal testing "

Characterization of metabolizing enzymes and biotransformation of selected test substances in human in-vitro skin models to identify an optimal test system for dermato-toxicological and exposure-related studies - Details of Characterization of metabolizing enzymes and biotransformation of selected test substances in human in-vitro skin models to identify an optimal test system for dermato-toxicological and exposure-related studies

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

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Improvement of an in vitro stem cell assay for developmental toxicity: Establishing molecular endpoints of tissue specific development - Details of Improvement of an in vitro stem cell assay for developmental toxicity: Establishing molecular endpoints of tissue specific development

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2000 - 2004

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In vitro tests for photogenotoxicity assessment as alternatives to photocarcinogenicity tests in ro-dents (Project part 1). - Details of In vitro tests for photogenotoxicity assessment as alternatives to photocarcinogenicity tests in ro-dents (Project part 1).

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2004

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Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials - Details of Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2007

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Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays - Details of Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Validation study for testing of skin penetration using biotechnologically devised human skin equivalents. Phase 2: Validation - Details of Validation study for testing of skin penetration using biotechnologically devised human skin equivalents. Phase 2: Validation

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

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