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Projects of "BfR Funding "

2009: Development of a method suited to identify epigenetic effects in cells in culture upon exposure to low doses of model compounds, 2010: Investigation of epigenetic effects of consumer product-related model compounds in vitro - Details of 2009: Development of a method suited to identify epigenetic effects in cells in culture upon exposure to low doses of model compounds, 2010: Investigation of epigenetic effects of consumer product-related model compounds in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

2009: Skin Penetration of Substances from Consumer Products 2010: Combined Migration and Skin Permeation of Phthalates from Consumer Products - Details of 2009: Skin Penetration of Substances from Consumer Products 2010: Combined Migration and Skin Permeation of Phthalates from Consumer Products

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

2010: Development and validation of an ELISA for the detection of Leptospira infection - Details of 2010: Development and validation of an ELISA for the detection of Leptospira infection

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2012

Funding Institutions:

Project Management Agency:

Activation of azo dyes to genotoxic metabolites by skin bacteria and studies for skin penetration - Details of Activation of azo dyes to genotoxic metabolites by skin bacteria and studies for skin penetration

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Additives that increase addicitivness and attractivness of tobacco products - Details of Additives that increase addicitivness and attractivness of tobacco products

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Advancement of toxicological study parameters in human cell cultures - Details of Advancement of toxicological study parameters in human cell cultures

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

Analysis of commercial Isoflavone Supplements - Details of Analysis of commercial Isoflavone Supplements

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Analysis of commercial Isoflavone Supplements - Details of Analysis of commercial Isoflavone Supplements

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Analysis of effects from trans-fatty acids on miRNA expression profiles of human colon cells - Details of Analysis of effects from trans-fatty acids on miRNA expression profiles of human colon cells

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Analysis of the effects of developmental toxins from consumer products on microRNA (miRNA) expression during differentiation of embryonic stem cells. Identification of novel molecular endpoints and studies on the role of miRNAs in developmental toxicity - Details of Analysis of the effects of developmental toxins from consumer products on microRNA (miRNA) expression during differentiation of embryonic stem cells. Identification of novel molecular endpoints and studies on the role of miRNAs in developmental toxicity

Executive Institute: BfR - Department 9: Experimental Toxicology and ZEBET (BfR - TOX) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Analysis of the migration of elastomers from food contact materials - Details of Analysis of the migration of elastomers from food contact materials

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Analysis of the variability of antibiotic resistance profiles in Campylobacter - Details of Analysis of the variability of antibiotic resistance profiles in Campylobacter

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Application of 2-DE-based proteomics for biomarker detection in human plasma - Details of Application of 2-DE-based proteomics for biomarker detection in human plasma

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2004

Funding Institutions:

Project Management Agency:

Application of 2-DE-based proteomics in vitro - Details of Application of 2-DE-based proteomics in vitro

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2004

Funding Institutions:

Project Management Agency:

Application of bacteriophages for the detection and isolation of pathogenic Y. enterocolitica strains in food - Details of Application of bacteriophages for the detection and isolation of pathogenic Y. enterocolitica strains in food

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Application of Bacteriophages for the Reduction of Campylobacter on Food - Details of Application of Bacteriophages for the Reduction of Campylobacter on Food

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Application of geographical information systems, GIS, for the analysis of epidemiological data - Details of Application of geographical information systems, GIS, for the analysis of epidemiological data

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2009

Funding Institutions:

Project Management Agency:

Array based analysis of endocrine-disrupting properties of selected plant protection products in the low dose range in vitro - Details of Array based analysis of endocrine-disrupting properties of selected plant protection products in the low dose range in vitro

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Assay of toxic compounds in smoke of water pipes - Details of Assay of toxic compounds in smoke of water pipes

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Behaviour of micro flora and pathogens following decontamination of poultry carcasses - Details of Behaviour of micro flora and pathogens following decontamination of poultry carcasses

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Bioavailability of 3-MCPD and 3-MCPD fatty acid esters - Details of Bioavailability of 3-MCPD and 3-MCPD fatty acid esters

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Bioavailability of coumarin from cinnamon and cinnamon-containing food (human study) - Details of Bioavailability of coumarin from cinnamon and cinnamon-containing food (human study)

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Bioavailability of cyanide from marzipan (human study) - Details of Bioavailability of cyanide from marzipan (human study)

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Biotechnological derived skin models for the cutaneous uptake of steroid hormone formulations - Details of Biotechnological derived skin models for the cutaneous uptake of steroid hormone formulations

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2003 - 2004

Funding Institutions:

Project Management Agency:

Breastfeeding behaviour of women after delivery in Berlin hospitals - Details of Breastfeeding behaviour of women after delivery in Berlin hospitals

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Carry over of nasal Methicillin resistant S. aureus (MRSA) on the carcass of slaughter pigs at the abbatoir - Details of Carry over of nasal Methicillin resistant S. aureus (MRSA) on the carcass of slaughter pigs at the abbatoir

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Cell cycle effects on the endocrine system and phase I metabolism - Details of Cell cycle effects on the endocrine system and phase I metabolism

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Characterisation and prevalidation of a new human cornea equivalent model for the evaluation of ocular toxicity - Details of Characterisation and prevalidation of a new human cornea equivalent model for the evaluation of ocular toxicity

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Characterisation of Campylobacter lari strains - Details of Characterisation of Campylobacter lari strains

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Characterisation of Salmonella Paratyphi B dT+ strains by phage typing - Details of Characterisation of Salmonella Paratyphi B dT+ strains by phage typing

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Characterization of biofilm formation by Listeria monocytogenes - Details of Characterization of biofilm formation by Listeria monocytogenes

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Characterization of cellular effects of contact sensitizers in vitro: Analysis of phosphotyrosine signaling pathways by far western blotting and establishment of a screening method - Details of Characterization of cellular effects of contact sensitizers in vitro: Analysis of phosphotyrosine signaling pathways by far western blotting and establishment of a screening method

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Characterization of Methicillin-resistent Staphylococcus aureus (MRSA) - isolates in respect of the presence of enterotoxin producing genes - Details of Characterization of Methicillin-resistent Staphylococcus aureus (MRSA) - isolates in respect of the presence of enterotoxin producing genes

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Characterization of predatory bacteria from the gastrointestinal tract of domestic animals - Details of Characterization of predatory bacteria from the gastrointestinal tract of domestic animals

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Characterization of the barrier function of human reconstructed skin models - Details of Characterization of the barrier function of human reconstructed skin models

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Chemical Imaging of Human Cells after Exposure to Metal Oxide Nanoparticles in vitro - Details of Chemical Imaging of Human Cells after Exposure to Metal Oxide Nanoparticles in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Collection of data fort he risk assessment on Salmonella in table eggs - Details of Collection of data fort he risk assessment on Salmonella in table eggs

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Computerised risk assessment of dermal absorption of active agents - Details of Computerised risk assessment of dermal absorption of active agents

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2008

Funding Institutions:

Project Management Agency:

Construction and Prevalidation of V79 Pathway Cell Lines: Heterologous Co-Expression of human Cytochrom P450 1A2 and polymorphic forms of human N-Acetyltransferase in V79 Chinese Hamster Cells for in vitro-studies on toxicity and metabolism of chemicals and drugs. - Details of Construction and Prevalidation of V79 Pathway Cell Lines: Heterologous Co-Expression of human Cytochrom P450 1A2 and polymorphic forms of human N-Acetyltransferase in V79 Chinese Hamster Cells for in vitro-studies on toxicity and metabolism of chemicals and drugs.

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2001 - 2004

Funding Institutions:

Project Management Agency:

Cost-benefit analysis of measures to reduce the prevalence of salmonella-serotyps in population of pigs for slaughter and the effect of determining maximum values for undesirable substances in animal nutrition - Details of Cost-benefit analysis of measures to reduce the prevalence of salmonella-serotyps in population of pigs for slaughter and the effect of determining maximum values for undesirable substances in animal nutrition

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Cumarine exposition: Cinnamon as ingredient of foodstuffs. Module 1: database children; Module 2: database adolescents/adults - Details of Cumarine exposition: Cinnamon as ingredient of foodstuffs. Module 1: database children; Module 2: database adolescents/adults

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Cytochrom P450 (CYP 2E1)-dependent metabolism in genetically modified cell lines - Details of Cytochrom P450 (CYP 2E1)-dependent metabolism in genetically modified cell lines

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Detection and characterization of noro- and rotaviruses of chicken as potential zoonotic food-borne pathogens - Details of Detection and characterization of noro- and rotaviruses of chicken as potential zoonotic food-borne pathogens

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Detection of Allergens in food: a comparative study on DNA-analytical and immunological methods - Details of Detection of Allergens in food: a comparative study on DNA-analytical and immunological methods

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Detection of Bacillus cereus toxins - Details of Detection of Bacillus cereus toxins

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Detection of non-coli/jejuni Campylobacter species in different food matrices - Details of Detection of non-coli/jejuni Campylobacter species in different food matrices

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Detection of Norovirus in clinical samples of human provenience, in environmental and food samples to investigate virus transmission routes - Details of Detection of Norovirus in clinical samples of human provenience, in environmental and food samples to investigate virus transmission routes

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

Detection of Viruses in Food using 'Molecularly Imprinted Polymers' - Details of Detection of Viruses in Food using 'Molecularly Imprinted Polymers'

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Determination of 2-and 3-MCPD-fatty acids esters in human milk - Details of Determination of 2-and 3-MCPD-fatty acids esters in human milk

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Determination of coumarin in different food samples - Details of Determination of coumarin in different food samples

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Determination of CYP2F-related enzyme activities in human lung tissue - Details of Determination of CYP2F-related enzyme activities in human lung tissue

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2011

Funding Institutions:

Project Management Agency:

Determination of fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD) in foodstuffs - Details of Determination of fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD) in foodstuffs

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2011

Funding Institutions:

Project Management Agency:

Determination of Flavophospholipol in feedingstuffs - Details of Determination of Flavophospholipol in feedingstuffs

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Determination of perfluorinated compounds in simulants for contact with fatty food (simulant D) - Details of Determination of perfluorinated compounds in simulants for contact with fatty food (simulant D)

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Determination of pyrrolizidine alkaloids in food and feed (Start-up funding of a research project BMELV) - Details of Determination of pyrrolizidine alkaloids in food and feed (Start-up funding of a research project BMELV)

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Determination of the isomerization and oxidation products from long-chain, polyunsaturated conjugated fatty acids in novel oils from the marine micro-alga - Details of Determination of the isomerization and oxidation products from long-chain, polyunsaturated conjugated fatty acids in novel oils from the marine micro-alga

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Determining the uptake of food additives by children and adolescents in Germany - Details of Determining the uptake of food additives by children and adolescents in Germany

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Developing analytical, imaging method for the identification of nanoparticles in cell lines (THP1 cells) as well as the elucidation of the effects obtained - Details of Developing analytical, imaging method for the identification of nanoparticles in cell lines (THP1 cells) as well as the elucidation of the effects obtained

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Developing analytical, imaging method for the identification of nanoparticles in cell lines (THP1 cells) as well as the elucidation of the effects obtained. - Details of Developing analytical, imaging method for the identification of nanoparticles in cell lines (THP1 cells) as well as the elucidation of the effects obtained.

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Development and evaluation of alternative methods to replace animal experiments (NIH-Test) for the potency measure of vaccines against rabies - Details of Development and evaluation of alternative methods to replace animal experiments (NIH-Test) for the potency measure of vaccines against rabies

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2010

Funding Institutions:

Project Management Agency:

Development and validation of a simple analytical method for quantification of mineral oil components MOSH and MOAH in foods based on conventional liquid chromatography and GC-FID - Details of Development and validation of a simple analytical method for quantification of mineral oil components MOSH and MOAH in foods based on conventional liquid chromatography and GC-FID

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Development and validation of a Trichinella Western Blot for for the certification of pigs from fattening farms - Details of Development and validation of a Trichinella Western Blot for for the certification of pigs from fattening farms

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Development and Validation of an Inductive Database for the Prediction of Carcinogenic Effects of Chemicals - Details of Development and Validation of an Inductive Database for the Prediction of Carcinogenic Effects of Chemicals

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2005

Funding Institutions:

Project Management Agency:

Development and validation of methods for the simultaneous determination of more than 500 pesticides in food and water using Q TRAP LC-MS/MS - Details of Development and validation of methods for the simultaneous determination of more than 500 pesticides in food and water using Q TRAP LC-MS/MS

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Development of a contact allergen-induced T-cell assay using Langerhans cells: 2009: Expression of lineage specific T-cell transcription factors as biological endpoint suitable to indicate chemical induction of sensitization 2010: Measurement and quantification of transcription factors via qRT-PCR and FACS - Details of Development of a contact allergen-induced T-cell assay using Langerhans cells: 2009: Expression of lineage specific T-cell transcription factors as biological endpoint suitable to indicate chemical induction of sensitization 2010: Measurement and quantification of transcription factors via qRT-PCR and FACS

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Development of a hepatic in vitro test system for the sensitive detection of pyrrolizidine alka-loids - Details of Development of a hepatic in vitro test system for the sensitive detection of pyrrolizidine alka-loids

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Development of a method applicable to § 64 LFGB for the detection and isolation of enterohaemorrhagic E. coli (EHEC) from plant foods - Details of Development of a method applicable to § 64 LFGB for the detection and isolation of enterohaemorrhagic E. coli (EHEC) from plant foods

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Development of a method of analysis for the determination of glyciol fatty acid estern in oil, fat and fat containing foodstuffs - Details of Development of a method of analysis for the determination of glyciol fatty acid estern in oil, fat and fat containing foodstuffs

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Development of a Real-Time PCR system for identification and typing of bacteria be-longing to the ?Cereus- Group? from food. - Details of Development of a Real-Time PCR system for identification and typing of bacteria be-longing to the ?Cereus- Group? from food.

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Development of a simple and universal analytical method for the simultaneous determination of pesticides in tap water - Details of Development of a simple and universal analytical method for the simultaneous determination of pesticides in tap water

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2007

Funding Institutions:

Project Management Agency:

Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances - Details of Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

Development of a Variable-Number Tandem-Repeats (VNTR) analysis method for the subtyping of Salmonella enterica serovar Infantis und Virchow - Details of Development of a Variable-Number Tandem-Repeats (VNTR) analysis method for the subtyping of Salmonella enterica serovar Infantis und Virchow

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Development of a Variable-Number-Tandem-Repeat Analysis (MLVA) typing system for Salmonella Enteritidis isolates - Details of Development of a Variable-Number-Tandem-Repeat Analysis (MLVA) typing system for Salmonella Enteritidis isolates

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Development of an analytical, imaging method for the determination and localisation of nanoparticles in a cell line (THP-1 cells) - Details of Development of an analytical, imaging method for the determination and localisation of nanoparticles in a cell line (THP-1 cells)

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2012

Funding Institutions:

Project Management Agency:

Development of an in vitro model (skin culture from slaughtered animals) to study the influence of compounds on wound healing. - Details of Development of an in vitro model (skin culture from slaughtered animals) to study the influence of compounds on wound healing.

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Development of analysis methods for the determination of ergot alkaloids and monitoring in selected food and feed - Details of Development of analysis methods for the determination of ergot alkaloids and monitoring in selected food and feed

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2009

Funding Institutions:

Project Management Agency:

Development of bioreactors for in vitro testing of biological heart valves for reduction of animal experiments - Details of Development of bioreactors for in vitro testing of biological heart valves for reduction of animal experiments

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Development of clean-up procedures for food samples as preparation of GC/C/IRMS measurements - Details of Development of clean-up procedures for food samples as preparation of GC/C/IRMS measurements

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2009

Funding Institutions:

Project Management Agency:

Development of methods for cleavage of azo dyes by human skin bacteria in vitro - Details of Development of methods for cleavage of azo dyes by human skin bacteria in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2006

Funding Institutions:

Project Management Agency:

Development of methods for the determination of ergot alkaloids including monitoring in food and feed - Details of Development of methods for the determination of ergot alkaloids including monitoring in food and feed

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2007

Funding Institutions:

Project Management Agency:

Development of methods for the isolation and analysis of Yessotoxin - Details of Development of methods for the isolation and analysis of Yessotoxin

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2003 - 2004

Funding Institutions:

Project Management Agency:

Development of new methods for the identification of animal proteins in feedingstuff. Real-time immuno-PCR for the detection of animal bone and tissue marker 2010: Validation of an immunological method for the detection of Osteocalcin representing a stable bone tissue marker in Meat and Bone Meal (MBM) - Details of Development of new methods for the identification of animal proteins in feedingstuff. Real-time immuno-PCR for the detection of animal bone and tissue marker 2010: Validation of an immunological method for the detection of Osteocalcin representing a stable bone tissue marker in Meat and Bone Meal (MBM)

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2010

Funding Institutions:

Project Management Agency:

Development of sample clean-up procedures preparing GC-C-IRMS measuremens of residues and contaminants in food - Details of Development of sample clean-up procedures preparing GC-C-IRMS measuremens of residues and contaminants in food

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2007

Funding Institutions:

Project Management Agency:

Development of screening assays for the assessment of the toxicity of migrants from commodities in keratinocytes - Details of Development of screening assays for the assessment of the toxicity of migrants from commodities in keratinocytes

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2006

Funding Institutions:

Project Management Agency:

Development, improvement and assessment of PCR methods for detection and subtyping of Yersinia - Details of Development, improvement and assessment of PCR methods for detection and subtyping of Yersinia

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Dietary trans-fatty acids: Role of nuclear receptors in risk evaluation of trans-fatty acids with regard to their effects in colorectal cancer - Details of Dietary trans-fatty acids: Role of nuclear receptors in risk evaluation of trans-fatty acids with regard to their effects in colorectal cancer

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Effect of folate oversupplementation on the methylation status of tumour suppressor genes in immortalized human colon epithelial cells. - Details of Effect of folate oversupplementation on the methylation status of tumour suppressor genes in immortalized human colon epithelial cells.

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Effect of folate oversupplementation on the proliferation and the expression of relevant genes in colon carcinoma cells - Details of Effect of folate oversupplementation on the proliferation and the expression of relevant genes in colon carcinoma cells

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Effects of different dietary Se-sources for cows on Se-bioavailability from their milk - Details of Effects of different dietary Se-sources for cows on Se-bioavailability from their milk

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Effects of High Pressure Treatment on fat and pathogens - Details of Effects of High Pressure Treatment on fat and pathogens

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2006

Funding Institutions:

Project Management Agency:

Effects of natural occuring fatty acids on the bioavailability and the metabolism of polycyclic aromatic hydrocarbons by taking the example of benzo[a]pyrene - Details of Effects of natural occuring fatty acids on the bioavailability and the metabolism of polycyclic aromatic hydrocarbons by taking the example of benzo[a]pyrene

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets - Details of Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Establishment and development of gentoxicity testing methods - Setup of the COMET assay for ingedients of product - Details of Establishment and development of gentoxicity testing methods - Setup of the COMET assay for ingedients of product

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals - Details of Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2010

Funding Institutions:

Project Management Agency:

Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures - Details of Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2009

Funding Institutions:

Project Management Agency:

Evaluation of endpoints in addition to MTT for predicting skin irritation potential of chemical substances with in vitro human reconstructed skin models. - Details of Evaluation of endpoints in addition to MTT for predicting skin irritation potential of chemical substances with in vitro human reconstructed skin models.

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2006

Funding Institutions:

Project Management Agency:

Evaluation of production methods for salami type sausages in the framework of risk assessment to evaluate the survival or growth of pathogens and the possible mycotoxin burdden of mould ripened sausages - Details of Evaluation of production methods for salami type sausages in the framework of risk assessment to evaluate the survival or growth of pathogens and the possible mycotoxin burdden of mould ripened sausages

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Evaluation of the genotoxic potenital of selected synthetically synthesized nanomaterials through application of alternative methods - Details of Evaluation of the genotoxic potenital of selected synthetically synthesized nanomaterials through application of alternative methods

Executive Institute: BfR - Department 9: Experimental Toxicology and ZEBET (BfR - TOX) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Examinations of poly- or perfluorinated compounds in food contact materials - Details of Examinations of poly- or perfluorinated compounds in food contact materials

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Exploratory study on the evaluation of the relationship betweenemissions from printers and copy machines in offices and health complaints - Details of Exploratory study on the evaluation of the relationship betweenemissions from printers and copy machines in offices and health complaints

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2006

Funding Institutions:

Project Management Agency:

Expression analysis of drug-metabolizing enzymes in human keratinocytes after treatment with selected xenobiotics - Details of Expression analysis of drug-metabolizing enzymes in human keratinocytes after treatment with selected xenobiotics

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Expression of xenobiotic metabolizing cytochrome P450 (CYP)-dependent monooxygenases in human keratinocytes and permanent skin cell cultures - Details of Expression of xenobiotic metabolizing cytochrome P450 (CYP)-dependent monooxygenases in human keratinocytes and permanent skin cell cultures

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Extension of an animal study on bioavailability and metabolisation of 3-MCPD esters - Details of Extension of an animal study on bioavailability and metabolisation of 3-MCPD esters

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Fatty acids as endocrine disruptors: Influence of chain length, branched chains and multiple bonds of fatty acids on the activity of the estrogen receptors ER-Alpha and ER-Beta - Details of Fatty acids as endocrine disruptors: Influence of chain length, branched chains and multiple bonds of fatty acids on the activity of the estrogen receptors ER-Alpha and ER-Beta

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Feeding of contaminated feed with melamine to laying hens to determine the carry over rate of melamine in eggs. - Details of Feeding of contaminated feed with melamine to laying hens to determine the carry over rate of melamine in eggs.

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Feeding of contaminated feed with tansy ragwort (Senecio jacobae) to small ruminants to determine the carry over rate of pyrrolizidine alkaloids in milk from small ruminants and to evaluate and validate a test method for the detection of PA´s in naturally contaminated samples - Details of Feeding of contaminated feed with tansy ragwort (Senecio jacobae) to small ruminants to determine the carry over rate of pyrrolizidine alkaloids in milk from small ruminants and to evaluate and validate a test method for the detection of PA´s in naturally contaminated samples

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Food authentication by Food-Fingerprinting with NMR spectroscopy and other spectroscopic techniques - Details of Food authentication by Food-Fingerprinting with NMR spectroscopy and other spectroscopic techniques

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Further development of a 3D-model of substance distribution in the cochlea after round window application - Details of Further development of a 3D-model of substance distribution in the cochlea after round window application

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2003 - 2004

Funding Institutions:

Project Management Agency:

Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies - Details of Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2008

Funding Institutions:

Project Management Agency:

Gene expression profiling to elucidate the cancerogenic effects of breakdown products of 1-Methoxyindol-3-methylglucosinolates (MIM-GL) from Brassica vegetables - Details of Gene expression profiling to elucidate the cancerogenic effects of breakdown products of 1-Methoxyindol-3-methylglucosinolates (MIM-GL) from Brassica vegetables

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Generation of norovirus-like particles as antigen for the development of detection systems for viruses in food - Details of Generation of norovirus-like particles as antigen for the development of detection systems for viruses in food

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Genetic investigation of rough Salmonella Enteritidis strains - Details of Genetic investigation of rough Salmonella Enteritidis strains

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Genetic polymorphisms and variability of cytochrom P450 enzymes - Details of Genetic polymorphisms and variability of cytochrom P450 enzymes

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2005

Funding Institutions:

Project Management Agency:

Genotoxicity of flavouring substances - Details of Genotoxicity of flavouring substances

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2006

Funding Institutions:

Project Management Agency:

Genotoxicity testing in 3D model ? Establishment and adaptation of the COMET assay using a model for bronchial epithelia exposed to ingredients of consumer products - Details of Genotoxicity testing in 3D model ? Establishment and adaptation of the COMET assay using a model for bronchial epithelia exposed to ingredients of consumer products

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Haemoglobin adducts of glycidol as marker of exposure of glycidol fatty acid esters:Development of methods and human trial - Details of Haemoglobin adducts of glycidol as marker of exposure of glycidol fatty acid esters:Development of methods and human trial

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Harmonisation of methods for the monitoring of VTEC and subtyping of stx2 genes - Details of Harmonisation of methods for the monitoring of VTEC and subtyping of stx2 genes

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Hepatotoxic combination effects of multiple residues of pesticides in vivo und in vitro - Details of Hepatotoxic combination effects of multiple residues of pesticides in vivo und in vitro

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2012 - 2012

Funding Institutions:

Project Management Agency:

HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study - Details of HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2008

Funding Institutions:

Project Management Agency:

Hydrolysis of flavouring substances - Details of Hydrolysis of flavouring substances

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2005

Funding Institutions:

Project Management Agency:

Identification of CYP2F1 and CYP2S1 in human lung tissue - Details of Identification of CYP2F1 and CYP2S1 in human lung tissue

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Identification of marker genes for important Listeria monocytogenes serotypes as a basis for the development of rapid molecular methods - Details of Identification of marker genes for important Listeria monocytogenes serotypes as a basis for the development of rapid molecular methods

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Identification of microsomal Epoxide hydrolase in human lung tissue - Details of Identification of microsomal Epoxide hydrolase in human lung tissue

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Identification of new molecular proteomic biomarker for the risk assessment of food related compounds; heat-tox products as important example (furan fatty acids and 3-MCPD) - Details of Identification of new molecular proteomic biomarker for the risk assessment of food related compounds; heat-tox products as important example (furan fatty acids and 3-MCPD)

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2008

Funding Institutions:

Project Management Agency:

Identification of novel molecular biomarkers enabling reliable assessment of endocrine distruptor activity in-vitro - Details of Identification of novel molecular biomarkers enabling reliable assessment of endocrine distruptor activity in-vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Identification of Nrf2-target genes in human THP-1 monocytes 2009: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis 2010: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis - Details of Identification of Nrf2-target genes in human THP-1 monocytes 2009: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis 2010: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis

Executive Institute: BfR - Department 9: Experimental Toxicology and ZEBET (BfR - TOX) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2010

Funding Institutions:

Project Management Agency:

Identification of protein-biomarkers in human- and mouse-plasma after exposure to Dioxin. - Details of Identification of protein-biomarkers in human- and mouse-plasma after exposure to Dioxin.

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Identification of proteins from spots of gel electrophoresis using mass spectrometry - Details of Identification of proteins from spots of gel electrophoresis using mass spectrometry

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2001 - 2007

Funding Institutions:

Project Management Agency:

Immunodetection of potential biomarkers for the prediction of early carcinogenic processes in the subacute toxicity test - Details of Immunodetection of potential biomarkers for the prediction of early carcinogenic processes in the subacute toxicity test

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Impact of chemical structure, physico-chemical substance properties, and study design on the dermal absorption rates of pesticidal/biocidal active ingredients - Details of Impact of chemical structure, physico-chemical substance properties, and study design on the dermal absorption rates of pesticidal/biocidal active ingredients

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Impact of the carbon chain length of perfluor carbonic acids toxicity and molecular charac-terisation of the hepatotoxic effects of PFOA on the proteomic level - Details of Impact of the carbon chain length of perfluor carbonic acids toxicity and molecular charac-terisation of the hepatotoxic effects of PFOA on the proteomic level

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2010

Funding Institutions:

Project Management Agency:

Importance of new emerging serogroups of STEC / EHEC as contaminants of foodstuffs and potential pathogens of humans in Germany - Details of Importance of new emerging serogroups of STEC / EHEC as contaminants of foodstuffs and potential pathogens of humans in Germany

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Improvement of methods of evaluation of communication programs - Details of Improvement of methods of evaluation of communication programs

Executive Institute: BfR - Department 2: Risk Communication (BfR - RIKO) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro - Details of Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2010

Funding Institutions:

Project Management Agency:

Improving the gain of transgenic mouse embryos for cryopreservation - Details of Improving the gain of transgenic mouse embryos for cryopreservation

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2006

Funding Institutions:

Project Management Agency:

In vitro exposure of lung cells with aerosol at the air-liquid-layer as an alternative for inhalation experiments with animals - Details of In vitro exposure of lung cells with aerosol at the air-liquid-layer as an alternative for inhalation experiments with animals

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2007

Funding Institutions:

Project Management Agency:

Induction and expression of Shiga Toxins in STEC and EHEC strains for their diagnosis and as parameter for risk assessment - Details of Induction and expression of Shiga Toxins in STEC and EHEC strains for their diagnosis and as parameter for risk assessment

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Infection kinetics and host specificity of methicillin-resistant Staphylococcus aureus (MRSA) in the pig - Details of Infection kinetics and host specificity of methicillin-resistant Staphylococcus aureus (MRSA) in the pig

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Influence of different extraction procedures on the recovery of pesticide residues analysed by liquid chromatographic methods - Details of Influence of different extraction procedures on the recovery of pesticide residues analysed by liquid chromatographic methods

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2004

Funding Institutions:

Project Management Agency:

Influence of endocrine disruptors using the example of soy isoflavones on the transformationof multipotent progenitor cells of the human mammary epithelium - Details of Influence of endocrine disruptors using the example of soy isoflavones on the transformationof multipotent progenitor cells of the human mammary epithelium

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Influence of simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) on the intestinal toxicity of silver nanoparticles - Details of Influence of simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) on the intestinal toxicity of silver nanoparticles

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Inhibition of the transcription factor Nrf2 as a putative mechanism of toxicity exerted by compounds from dyes, glues and vulcanization accelerators in human keratinocytes (HaCaT) - Details of Inhibition of the transcription factor Nrf2 as a putative mechanism of toxicity exerted by compounds from dyes, glues and vulcanization accelerators in human keratinocytes (HaCaT)

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Interactions of silver-nanoparticles with cellular membrane proteins – influence of the stabilizers to form a protein corona and particle-toxicity - Details of Interactions of silver-nanoparticles with cellular membrane proteins – influence of the stabilizers to form a protein corona and particle-toxicity

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

International Validation of a new gas-chromatographic method for effective determination of pesticide residues - Details of International Validation of a new gas-chromatographic method for effective determination of pesticide residues

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2004

Funding Institutions:

Project Management Agency:

Interspecies variability between man, rabbit and rat in function and structure of major xenobiotic transport proteins in the placenta - Details of Interspecies variability between man, rabbit and rat in function and structure of major xenobiotic transport proteins in the placenta

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Investigation of biomarkers of water pipe smoke - Details of Investigation of biomarkers of water pipe smoke

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Investigation of cytotoxicity and genotoxicity of water pipe smoke - Details of Investigation of cytotoxicity and genotoxicity of water pipe smoke

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Investigation of food products illegally introduced into Germany by airport luggage for the presence of the non-endemic pathogens Brucella and ('2010:Trichinella'). - Details of Investigation of food products illegally introduced into Germany by airport luggage for the presence of the non-endemic pathogens Brucella and ('2010:Trichinella').

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Investigation of occurrence, types and human pathogenicity of Shiga- toxin producing Escherichia coli (STEC) in meat samples from wild-life animals as a basis for risk assessment - Details of Investigation of occurrence, types and human pathogenicity of Shiga- toxin producing Escherichia coli (STEC) in meat samples from wild-life animals as a basis for risk assessment

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Investigation of potential (risk) communication problems in the use of 'risk' and 'hazard' and derivation of recommendations for action - Details of Investigation of potential (risk) communication problems in the use of 'risk' and 'hazard' and derivation of recommendations for action

Executive Institute: BfR - Department 2: Risk Communication (BfR - RIKO) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Investigation of Shiga-toxin 2e (Stx2e) producing strains of Escherichia coli as potential human pathogenic bacteria and their significance as contaminants in the food chain - Details of Investigation of Shiga-toxin 2e (Stx2e) producing strains of Escherichia coli as potential human pathogenic bacteria and their significance as contaminants in the food chain

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Investigation of the residue behavior of different antibiotics in aqua-cultured shrimps - Details of Investigation of the residue behavior of different antibiotics in aqua-cultured shrimps

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Investigation of the storage stability of pesticides - Details of Investigation of the storage stability of pesticides

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Investigation of uptake, accumulation and distribution of malachite green in aquacultured fish - Details of Investigation of uptake, accumulation and distribution of malachite green in aquacultured fish

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Investigation on contamination of raw consumed food of vegetable origin with VTEC / STEC / EHEC using serological and molecular detection methods - Details of Investigation on contamination of raw consumed food of vegetable origin with VTEC / STEC / EHEC using serological and molecular detection methods

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Investigations in vitro on structure-activity-relationship with respect to a teratogenic potential of flavouring substances - Details of Investigations in vitro on structure-activity-relationship with respect to a teratogenic potential of flavouring substances

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Investigations of food (milk) for Listeria spp - Details of Investigations of food (milk) for Listeria spp

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Investigations of the mechanism of matrix effects occurring during ionization in LC-MS/MS instruments. Development of proposals to enhance the accuracy of residue determinations. - Details of Investigations of the mechanism of matrix effects occurring during ionization in LC-MS/MS instruments. Development of proposals to enhance the accuracy of residue determinations.

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2011

Funding Institutions:

Project Management Agency:

Investigations of the microbial status of caviar from the retail market and wholesale with special emphasis of the occurrence of aquatic mycobacteria. - Details of Investigations of the microbial status of caviar from the retail market and wholesale with special emphasis of the occurrence of aquatic mycobacteria.

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Investigations on metabolism of the skin with in vitro models - Details of Investigations on metabolism of the skin with in vitro models

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Investigations on the carry over of Maduramicin from feed to egg - Details of Investigations on the carry over of Maduramicin from feed to egg

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Investigations on the use of phytogenic feed additives in animal nutrition - Details of Investigations on the use of phytogenic feed additives in animal nutrition

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Isolation and characterization of the origin of transfer (oriT) of the Yersinia virulence plasmid pYV - Details of Isolation and characterization of the origin of transfer (oriT) of the Yersinia virulence plasmid pYV

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

List of chemicals with missing IC 50-values and/or LD 50-values - Details of List of chemicals with missing IC 50-values and/or LD 50-values

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2004

Funding Institutions:

Project Management Agency:

Long-term study in pigs infected with salmonella - Details of Long-term study in pigs infected with salmonella

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

MALDI-TOF MS-based identification of microorganisms from complex samples - Details of MALDI-TOF MS-based identification of microorganisms from complex samples

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Marine Biotoxins: Analysis of the toxic effects of okadaic acid metabolites. Follow-up of Development of an in-vitro screening test of marine toxins based on embryonic stem cells - Details of Marine Biotoxins: Analysis of the toxic effects of okadaic acid metabolites. Follow-up of Development of an in-vitro screening test of marine toxins based on embryonic stem cells

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2011

Funding Institutions:

Project Management Agency:

Masked mycotoxins: Exposition of the German consumer by Zearalenone-glycosides in food - Details of Masked mycotoxins: Exposition of the German consumer by Zearalenone-glycosides in food

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2005

Funding Institutions:

Project Management Agency:

Mass spectrometric characterisation/identification of microbial pathogens of Vibrio spp. '2010: Yersinia enterocolitica' - Details of Mass spectrometric characterisation/identification of microbial pathogens of Vibrio spp. '2010: Yersinia enterocolitica'

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2010

Funding Institutions:

Project Management Agency:

Mechanism of toxicity of triazole fungicides - Details of Mechanism of toxicity of triazole fungicides

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Metabolic activity in raw milk-biofilms with Listeria monocytogenes after a sub-optimal clean-ing with hydrogen peroxide - Details of Metabolic activity in raw milk-biofilms with Listeria monocytogenes after a sub-optimal clean-ing with hydrogen peroxide

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Metabolism of polyaromatic hydrocarbons by the microbiome of the skin - Details of Metabolism of polyaromatic hydrocarbons by the microbiome of the skin

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Method development for the characterisation and quantification of toxic volatile impurities from consumer goods, transported in fumigated shipping containers - Details of Method development for the characterisation and quantification of toxic volatile impurities from consumer goods, transported in fumigated shipping containers

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Method development for the identification of biomarkers for risk assessment of endocrine disruptors and phthalates - Details of Method development for the identification of biomarkers for risk assessment of endocrine disruptors and phthalates

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Microbial stress response of Campylobacter jejuni and its role in food processing - Details of Microbial stress response of Campylobacter jejuni and its role in food processing

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

Mobile genetic elements of Brucella - bacteriophages - Details of Mobile genetic elements of Brucella - bacteriophages

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Molecular characterization of porcine Campylobacter (C.) coli population. Extension of data situation as a precondition for the creation of risk assessment for C. coli - Details of Molecular characterization of porcine Campylobacter (C.) coli population. Extension of data situation as a precondition for the creation of risk assessment for C. coli

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Molecular characterization of the interaction between perfluoroctanoic acid (PFOA) and the hepatocyte nuclear factor 4alpha (HNF4alpha) - Details of Molecular characterization of the interaction between perfluoroctanoic acid (PFOA) and the hepatocyte nuclear factor 4alpha (HNF4alpha)

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Molecular detection of the highly pathogenic zoonotic agent Brucella in cheese samples originating from endemic countries. - Details of Molecular detection of the highly pathogenic zoonotic agent Brucella in cheese samples originating from endemic countries.

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Molecular effects of flavonoid quercetin on human primary hepatocytes compared to those in mouse liver - Details of Molecular effects of flavonoid quercetin on human primary hepatocytes compared to those in mouse liver

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2014

Funding Institutions:

Project Management Agency:

Molecular epidemiology of MRSA from livestock ? detailed characterization and typing of isolates for the deduction of epidemiological correlations - Details of Molecular epidemiology of MRSA from livestock ? detailed characterization and typing of isolates for the deduction of epidemiological correlations

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Molecular mechanisms of furan-mediated liver toxicity - Details of Molecular mechanisms of furan-mediated liver toxicity

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Molecular Risk Assessment of Shiga Toxin producing E. coli (STEC) from food and of attaching and effacing E. coli (AEEC) in regard to their human virulence and as a reservoir of new emerging enterohaemorrhagic E. coli types. - Details of Molecular Risk Assessment of Shiga Toxin producing E. coli (STEC) from food and of attaching and effacing E. coli (AEEC) in regard to their human virulence and as a reservoir of new emerging enterohaemorrhagic E. coli types.

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Molecular subtyping of Listeria monocytogenes using pulsed-field gel electrophoresis (PFGE) - Details of Molecular subtyping of Listeria monocytogenes using pulsed-field gel electrophoresis (PFGE)

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Molecular typing as an alternative method for the serological determination of flagellar antigens in E. coli - Details of Molecular typing as an alternative method for the serological determination of flagellar antigens in E. coli

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Molecularkinetic characterization of the transport and the distribution of the pro-carcinogene Benzo[a]pyrene in vitro and in vivo ? new kinetic data for risk assessment - Details of Molecularkinetic characterization of the transport and the distribution of the pro-carcinogene Benzo[a]pyrene in vitro and in vivo ? new kinetic data for risk assessment

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Multiplex real-time PCR rapid method for serovar-typing and quantification of salmonellae - Details of Multiplex real-time PCR rapid method for serovar-typing and quantification of salmonellae

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Mutagenicity and toxicity of water pipe smoke - Details of Mutagenicity and toxicity of water pipe smoke

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2009

Funding Institutions:

Project Management Agency:

Nanoproducts for Plant Care and Protection - Details of Nanoproducts for Plant Care and Protection

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Normal human neural progenitorcells as a screening model for substances that are toxic for neural development. - Details of Normal human neural progenitorcells as a screening model for substances that are toxic for neural development.

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2007

Funding Institutions:

Project Management Agency:

Nrf2-deficient human cell lines as a biological tool to screen for compounds of toxicological concern in consumer products. - Details of Nrf2-deficient human cell lines as a biological tool to screen for compounds of toxicological concern in consumer products.

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models - Details of Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Perfuoroalkyl and polyfluoroalkyl substances in breast milk: Contents, time trends, relevance of influencing factors including individual consumption patterns and assessment for the breast fed infant - Details of Perfuoroalkyl and polyfluoroalkyl substances in breast milk: Contents, time trends, relevance of influencing factors including individual consumption patterns and assessment for the breast fed infant

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2014

Funding Institutions:

Project Management Agency:

Pilot study investigating Leptospira serovars in wild boars - Details of Pilot study investigating Leptospira serovars in wild boars

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Preparation for external prevalidation: Optimization of the internally validated and standardized method for quantitation of angiogenesis and antiangiogenesis in vitro by determination of the angiogenic standard of the cells to be used - Details of Preparation for external prevalidation: Optimization of the internally validated and standardized method for quantitation of angiogenesis and antiangiogenesis in vitro by determination of the angiogenic standard of the cells to be used

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2010

Funding Institutions:

Project Management Agency:

Prevalence and diversity among temperate bacteriophages (prophages) in the genome of methicillin-resistent staphylococcus aureus (MRSA) isolates from the food-chain - Details of Prevalence and diversity among temperate bacteriophages (prophages) in the genome of methicillin-resistent staphylococcus aureus (MRSA) isolates from the food-chain

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Prevalidation of human cornea model based on immortalized corneal cell lines as in vitro alternative to the Draize eye test. - Details of Prevalidation of human cornea model based on immortalized corneal cell lines as in vitro alternative to the Draize eye test.

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Production of textiles with defined composition and investigation of migrates - Details of Production of textiles with defined composition and investigation of migrates

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Proof of sensitization in human dendritic cells of the skin in a migration assay and induction of T cell response in in-vitro models without animal experiments - Details of Proof of sensitization in human dendritic cells of the skin in a migration assay and induction of T cell response in in-vitro models without animal experiments

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Proteomanalyses of different liver tumors of mice with activating mutations in the oncogenes ß-Catenin, Ha-Ras and B-Raf - Details of Proteomanalyses of different liver tumors of mice with activating mutations in the oncogenes ß-Catenin, Ha-Ras and B-Raf

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2006

Funding Institutions:

Project Management Agency:

Proteome analysis of liver cells from Beta-catenin-mutated mice as a tool to get insight into the role of the oncoprotein for the tumor promotion by chemical substances - Details of Proteome analysis of liver cells from Beta-catenin-mutated mice as a tool to get insight into the role of the oncoprotein for the tumor promotion by chemical substances

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2008

Funding Institutions:

Project Management Agency:

Proteomic analysis into molecular toxicological effects of nano particles in human intestinal Caco-2 cells - Details of Proteomic analysis into molecular toxicological effects of nano particles in human intestinal Caco-2 cells

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Proteomic analysis of benzo(a)pyrene responses in mouse tissues - Details of Proteomic analysis of benzo(a)pyrene responses in mouse tissues

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2005

Funding Institutions:

Project Management Agency:

Proteomic analysis of cellular changes after treatment with contact allergens in human monocytic cell lines and in primary dendritic cells - Details of Proteomic analysis of cellular changes after treatment with contact allergens in human monocytic cell lines and in primary dendritic cells

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Proteomic analysis of effects induced by 3-MCPD and 3-MCPD fatty acid esters in rat liver and kidney - Details of Proteomic analysis of effects induced by 3-MCPD and 3-MCPD fatty acid esters in rat liver and kidney

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Proteomic analysis of oxidative stress after nanoparticle treatment in cell culture to study cytotoxicity mechanisms - Details of Proteomic analysis of oxidative stress after nanoparticle treatment in cell culture to study cytotoxicity mechanisms

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Proteomic investigations into 2-MCPD and 2-MCPD-distearate-induced effects after 28-days subacute oral treatment in rats - Details of Proteomic investigations into 2-MCPD and 2-MCPD-distearate-induced effects after 28-days subacute oral treatment in rats

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2014

Funding Institutions:

Project Management Agency:

Proteomic investigations into silver nanoparticle-induced effects after 28-days subacute oral treatment in rats - Details of Proteomic investigations into silver nanoparticle-induced effects after 28-days subacute oral treatment in rats

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2014

Funding Institutions:

Project Management Agency:

Proteomic investigations of carcinogenic effects in primary rat hepatocytes: prevalidation of an in vitro hepatic model for detection of non-genotoxic carcinogens - Details of Proteomic investigations of carcinogenic effects in primary rat hepatocytes: prevalidation of an in vitro hepatic model for detection of non-genotoxic carcinogens

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

Funding Institutions:

Project Management Agency:

Qualitative and quantitative analysis of toxicological relevant matters in the mainstream smoke of the waterpipe - Details of Qualitative and quantitative analysis of toxicological relevant matters in the mainstream smoke of the waterpipe

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Quantification of residues of coccidiostats in feed and food of animal origin caused by carry over from contaminated feed. - Details of Quantification of residues of coccidiostats in feed and food of animal origin caused by carry over from contaminated feed.

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2010

Funding Institutions:

Project Management Agency:

Quantitative and qualitative detection of foodborne pathogens using real-time PCR and typing of the pathogens with DNA microarray - Details of Quantitative and qualitative detection of foodborne pathogens using real-time PCR and typing of the pathogens with DNA microarray

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Rat hepatitis E virus as a model virus for studies on stability, pathogenicity and transmission pathways of human hepatitis E viruses - Details of Rat hepatitis E virus as a model virus for studies on stability, pathogenicity and transmission pathways of human hepatitis E viruses

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Refinement of the LCSA (loose-fit coculture-based sensitization assay) - Details of Refinement of the LCSA (loose-fit coculture-based sensitization assay)

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2008

Funding Institutions:

Project Management Agency:

Replacement of fetal calf serum in the embryonic stem cell test (EST) – Standardization of culture conditions for proliferation and differentiation of embryonic stem cells of the mouse - Details of Replacement of fetal calf serum in the embryonic stem cell test (EST) – Standardization of culture conditions for proliferation and differentiation of embryonic stem cells of the mouse

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2007

Funding Institutions:

Project Management Agency:

Reporter gene assays in permanent cell lines as screening tools for the detection of food contaminants - Details of Reporter gene assays in permanent cell lines as screening tools for the detection of food contaminants

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency:

Reviewing the application of Hydrophilic Interaction Chromatography (HILIC) for the determination of highly polar and ionic pesticide active ingredients - Details of Reviewing the application of Hydrophilic Interaction Chromatography (HILIC) for the determination of highly polar and ionic pesticide active ingredients

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2009

Funding Institutions:

Project Management Agency:

Risk assessment for evaluation of STEC contamination in food - Details of Risk assessment for evaluation of STEC contamination in food

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

Funding Institutions:

Project Management Agency:

Risk potential determination of Salmonella Paratyphi B dT+ strains for animals and humans - Details of Risk potential determination of Salmonella Paratyphi B dT+ strains for animals and humans

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Scented toys: Exposure of infants against allergenic scents - Research on the analysis and biological effects of allergens in toys - Details of Scented toys: Exposure of infants against allergenic scents - Research on the analysis and biological effects of allergens in toys

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Screening assays for toxic and sensitizing substances in mixtures of azo dyes and its metabolites using human keratinocytes - Details of Screening assays for toxic and sensitizing substances in mixtures of azo dyes and its metabolites using human keratinocytes

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Second Generation Subtyping within the European Network PulseNet Europe: Development and Validation of a Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA) System for Non-O157 Shiga Toxin-Producing Escherichia coli - Details of Second Generation Subtyping within the European Network PulseNet Europe: Development and Validation of a Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA) System for Non-O157 Shiga Toxin-Producing Escherichia coli

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

siRNA technology in mammalian cells as alternative of knock-out mice: Functional investigations of proteins of the Myc-Miz-1-TopBP1-network (translation). - Details of siRNA technology in mammalian cells as alternative of knock-out mice: Functional investigations of proteins of the Myc-Miz-1-TopBP1-network (translation).

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2003 - 2004

Funding Institutions:

Project Management Agency:

Skin penetration in vitro - Details of Skin penetration in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2008

Funding Institutions:

Project Management Agency:

Species-dependent formation of okadaic acid metabolites in the liver and identification of involved xenobiotic-metabolizing enzymes - Details of Species-dependent formation of okadaic acid metabolites in the liver and identification of involved xenobiotic-metabolizing enzymes

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Storage of deep frozen meat with special regard to human health and quality aspects - Details of Storage of deep frozen meat with special regard to human health and quality aspects

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

Project Management Agency:

Studies on skin penetration of ingredients of cosmetics and commodities using in-vitro methods - Details of Studies on skin penetration of ingredients of cosmetics and commodities using in-vitro methods

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2007

Funding Institutions:

Project Management Agency:

Studies on the allergenic potential ingredients of commedities and cosmetics using the local lymph node assay - Details of Studies on the allergenic potential ingredients of commedities and cosmetics using the local lymph node assay

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2005

Funding Institutions:

Project Management Agency:

Studies on the anti-oxidative responses of lung cells as an endpoint for the assessment of aerosols after exposure at the air-liquid interface - Details of Studies on the anti-oxidative responses of lung cells as an endpoint for the assessment of aerosols after exposure at the air-liquid interface

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2011

Funding Institutions:

Project Management Agency:

Studies on the growth kinetics of Vibrio spp. in different matrices - Details of Studies on the growth kinetics of Vibrio spp. in different matrices

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Studies on the metabolism of azo dyes in clothing textiles and cosmetics: Evidence of azo cleavage by skin bacteria and characterization of metabolites - Details of Studies on the metabolism of azo dyes in clothing textiles and cosmetics: Evidence of azo cleavage by skin bacteria and characterization of metabolites

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2005

Funding Institutions:

Project Management Agency:

Studies on the occurrence of infections with pathogens of the Mycobacterium avium-intracellulare complex (mycobacteriosis) in slaughter pigs - Details of Studies on the occurrence of infections with pathogens of the Mycobacterium avium-intracellulare complex (mycobacteriosis) in slaughter pigs

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Studies on toxicity and genotoxicity of substances from commodities, e.g. azo dyes and vulcanisation aids - Details of Studies on toxicity and genotoxicity of substances from commodities, e.g. azo dyes and vulcanisation aids

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2002 - 2007

Funding Institutions:

Project Management Agency:

Study on leptospirosis prevalence in dogs and humans - Details of Study on leptospirosis prevalence in dogs and humans

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Support of the national broiler campylobacter monitoring - Details of Support of the national broiler campylobacter monitoring

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

Funding Institutions:

Project Management Agency:

Tattoo inks: chemical characterization and distribution in the human skin - Details of Tattoo inks: chemical characterization and distribution in the human skin

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Temperate phages of Campylobacter jejuni - Details of Temperate phages of Campylobacter jejuni

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

Testing of Salmonella and E. coli isolates from pigs concerning their copper and zinc resistance - Details of Testing of Salmonella and E. coli isolates from pigs concerning their copper and zinc resistance

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

The effect of different sea water parameters on the formation of disinfection by-products anddisinfection efficiency - Details of The effect of different sea water parameters on the formation of disinfection by-products anddisinfection efficiency

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2012

Funding Institutions:

Project Management Agency:

The inflammatory milieu in human skin affected by chemical contact allergens - Details of The inflammatory milieu in human skin affected by chemical contact allergens

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

The influence of different acrylamide concentrations on the transcription of selected genes in cell cultures analyzed by microarrays. Analysis of the biofunctionality of acrylamide - Details of The influence of different acrylamide concentrations on the transcription of selected genes in cell cultures analyzed by microarrays. Analysis of the biofunctionality of acrylamide

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

Funding Institutions:

Project Management Agency:

The isolated perfused bovine udder as an in vitro model for the evaluation of sensibilisation/sensitisation induced by chemicals - Details of The isolated perfused bovine udder as an in vitro model for the evaluation of sensibilisation/sensitisation induced by chemicals

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2004 - 2006

Funding Institutions:

Project Management Agency:

Toxin production of Vibrio spp. - Details of Toxin production of Vibrio spp.

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

Funding Institutions:

Project Management Agency:

Transfer and transformation of DSP toxins in blue mussels (Mytilus edulis L.) - Details of Transfer and transformation of DSP toxins in blue mussels (Mytilus edulis L.)

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

Funding Institutions:

Project Management Agency:

Type IV secretion in Yersinia: Occurrence, molecular characterization and genotyping of Yersinia isolates harbouring a conjugative type IV system - Details of Type IV secretion in Yersinia: Occurrence, molecular characterization and genotyping of Yersinia isolates harbouring a conjugative type IV system

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2007

Funding Institutions:

Project Management Agency:

Uptake and toxicity of nanoparticles regarding coating and ion release in Caco-2-coculture - Details of Uptake and toxicity of nanoparticles regarding coating and ion release in Caco-2-coculture

Executive Institute: BfR - Department 5: Food Safety (BfR - LMS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Use of the high resolution Exactive mass spectrometer for the residue analysis of pharmacologically active substances (Transfer of pharmacologically active substances into food of plant origin) - Details of Use of the high resolution Exactive mass spectrometer for the residue analysis of pharmacologically active substances (Transfer of pharmacologically active substances into food of plant origin)

Executive Institute: BfR - Department 8: Safety in the Food Chain (BfR - SIN) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

Funding Institutions:

Project Management Agency:

Use of transgenic animals in biomedical research in Germany - survey 2001 to 2003 and perspectives to change research to non-animal test methods - Details of Use of transgenic animals in biomedical research in Germany - survey 2001 to 2003 and perspectives to change research to non-animal test methods

Executive Institute: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2003 - 2004

Funding Institutions:

Project Management Agency:

Validation of the BfR in-house ELISA for the detection of Leptospira infection originating from foreign countries - Details of Validation of the BfR in-house ELISA for the detection of Leptospira infection originating from foreign countries

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2013 - 2013

Funding Institutions:

Project Management Agency:

Variability of cytochrom P450 enzymes in human lung tissue - Details of Variability of cytochrom P450 enzymes in human lung tissue

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2001 - 2006

Funding Institutions:

Project Management Agency:

VetCAb: Representative collection of consumption amounts of antibiotics in food-producing animals. Conception and preparation of a pilot study - Details of VetCAb: Representative collection of consumption amounts of antibiotics in food-producing animals. Conception and preparation of a pilot study

Executive Institute: BfR - Department 4: Biological Safety (BfR - BIOS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2011

Funding Institutions:

Project Management Agency: