FBN Research Unit Molecular Biology
The Research Unit Molecular Biology aims to elucidate genetic and epigenetic mechanisms of expression and inheritance of selected traits, in order to develop more efficient selection tools to improve sustainability and productivity of animal breeding. Therefore functional and structural genomic approaches are integrated in the main research areas and strategies: - making use of functional biodiversity among populations in map-based approaches to analyse the genetic control of phenotypic variation and to identify candidate genes - function-driven identification and analysis of candidate genes and of the hierarchical interaction of super- and subordinated components within the functional network. These top-down and bottom-up approaches are used to contribute to the genetic improvement of animal health, fitness, adaptability, fertility, and traits related to product quality.
Parent institution:
Leibniz Institute for Farm Animal Biology (FBN) Details of FBN
Address
FBN Research Unit Molecular Biology
Wilhelm-Stahl-Allee 2
D-18196 Dummerstorf
Mecklenburg-Vorpommern
Phone: +49 38208 68700
Fax: +49 38208 68702
email: wimmers(@)fbn-dummerstorf.de
Activities:
- Research
Focus of Research:
- 1. Area of research: Identification and characterisation of genome regions affecting complex traits using segregating family structures in farm animals (QTL regions)
- 2. Area of research: Integration of structural and functional genomics for the identification and characterisation of genes influencing complex traits (Genomics)
- 3. Area of research: Structural Analyses of Candidate Genes for Significant Performances in Farm Animal Breeding (Gene analysis)
- 4. Area of research: Analysis of regulatory mechanisms of selected genes influencing performance of farm animals (Gene expression)
Coordinated projects
- Collaborative project: FUGATO-plus - GENE-FL - Genetic Foundations foundation of stability for beef, pork, horse and sheep; subprojects FBN: Genomic Approaches for leg weakness in pigs, OC / OCD at the horse and Laminitis (Klauenrehe) in cattle Details of Collaborative project: FUGATO-plus - GENE-FL - Genetic Foundations foundation of stability for beef, pork, horse and sheep; subprojects FBN: Genomic Approaches for leg weakness in pigs, OC / OCD at the horse and Laminitis (Klauenrehe) in cattle
- Collaborative project: FUGATO-plus - MeGA-M - Metabolomische and genomic analysis of milk for healthy dairy cows; project FBN Details of Collaborative project: FUGATO-plus - MeGA-M - Metabolomische and genomic analysis of milk for healthy dairy cows; project FBN
- Determination of causes of bovine neonatal Pancytopenie Details of Determination of causes of bovine neonatal Pancytopenie
- Elucidating the aetiology of hereditary diseases in the pig by integrating structural and functional genomics Details of Elucidating the aetiology of hereditary diseases in the pig by integrating structural and functional genomics
- Pathogen-specific signal transduction in the mammary gland epithelial cell Details of Pathogen-specific signal transduction in the mammary gland epithelial cell
Coordinated collaborative projects:
- FOR 585: pathogen-specific defense mechanisms in the mammary gland Details of FOR 585: pathogen-specific defense mechanisms in the mammary gland