FLI - Institute for Bacterial Infections and Zoonoses (FLI-IBIZ)
The Institute for Bacterial Infections and Zoonoses carries out research in the fields of etilogy and control of infectious animal diseases. Thus, investigations on pathogenesis, diagnosis and epidemiology of these diseases are also done. An important part of activities is directed towards diseases and their causative agents originating from animals and posing direct or indirect health risks to man. The institute pursues current developments in animal husbandry and control of zoonoses in order to identify risks to animals and man in advance. The spectrum of activities comprises notifiable animal diseases but also other diseases of great economic relevance and zoonoses. Besides farm animals, pet and zoo animals as well as wildlife are subjects of research and service work. The results of these activities will serve the development and optimisation of diagnostic procedures and the design of control strategies. Research projects are focusing on infections caused by Salmonellae, Campylobacter, Brucellae, Clostridia, Francisellae, Burkholderiae, Mycoplasma and selected viral agents. The following topics are: investigations on prevalence, characterisation of transmission routes and mechanisms, aspects of pathogen persistence, elucidation of infection chains and epidemiological relationships using classical and molecular methods, assessing of zoonotic importance, establishing animal infection models and examination of therapeutics using these models. The majority of research projects is done in close collaboration with the Institute for Molecular Pathogenesis. Official tasks include national reference laboratories for brucellosis, contagious equine metritis, anthrax, black leg, bovine genital campylobacteriosis, glanders, bovine salmonellosis, and tick-borne diseases.
Parent institution:
Friedrich-Loeffler-Institute - Federal Research Institute for Animal Health (FLI) Details of FLI
Address
FLI - Institute for Bacterial Infections and Zoonoses (FLI-IBIZ)
Naumburger Straße 96a
07743 Jena Jena
Mecklenburg-Vorpommern
Phone: +49 3641 804 200
Fax: +49 3641 804 228
email: Heinrich.Neubauer(@)fli.bund.de
Activities:
- Research
Focus of Research:
- Campylobacter
- Contagious Bovine Pleuropneumonia (CBPP)
- L3-agents
- Rotaviruses and Noroviruses
- Salmonellosis
- Tick-borne diseases
Coordinated projects
- Collaborative project: Novel approach for the development of a heterosubtypic marker vaccine against avian influenza in poultry – Subproject 2 Details of Collaborative project: Novel approach for the development of a heterosubtypic marker vaccine against avian influenza in poultry – Subproject 2
- Comparative testing of diagnostic of botulism in Germany Details of Comparative testing of diagnostic of botulism in Germany
- D11.11 To identify fitness factors that confer the ability of Yersiniae to highly replicate under harsh host tissue specific conditions e.g. anaerobic/hypoxic condition as a basis for efficient human-to-human transmission Details of D11.11 To identify fitness factors that confer the ability of Yersiniae to highly replicate under harsh host tissue specific conditions e.g. anaerobic/hypoxic condition as a basis for efficient human-to-human transmission
- Importance of Clostridium botulinum in chronic incidence of disease - Detection of Clostridium botulinum and Clostridium botulinum neurotoxin Details of Importance of Clostridium botulinum in chronic incidence of disease - Detection of Clostridium botulinum and Clostridium botulinum neurotoxin
- Influence of climate change on the transmission of vectors (here: Ixodidae) Details of Influence of climate change on the transmission of vectors (here: Ixodidae)
- Investigation in broiler chicks with diarrhea followed by growth depression (malabsorption syndrome, MAS) Details of Investigation in broiler chicks with diarrhea followed by growth depression (malabsorption syndrome, MAS)
- Mechanisms of colonization and adhesion on chicken intestinal epithelial cells by Campylobacter jejuni Details of Mechanisms of colonization and adhesion on chicken intestinal epithelial cells by Campylobacter jejuni
- Pathogenesis of mycoplasma diseases in cattle Details of Pathogenesis of mycoplasma diseases in cattle
- Salmonella-free broilers by live-vaccine-induced innate resistance to colonisation and invasion and novel methods to eleminate vaccine and field strains Details of Salmonella-free broilers by live-vaccine-induced innate resistance to colonisation and invasion and novel methods to eleminate vaccine and field strains
Involved in research projects:
- Importance of Clostridium botulinum in chronic incidence of disease Details of Importance of Clostridium botulinum in chronic incidence of disease