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SFB 670 TP2: Molecular mechanisms of host cell entry by phytopathogenic powdery mildew fungi via suppression of cell-autonomous plant defence

Description:

Isoforms of plasma membrane-localized MLO and SNARE proteins are plant polypeptides involved in the regulation of host cell entry by phytopathogenic powdery mildew fungi. MLO and t-SNAREs (syntaxins) interact with each other and are part of a plasma membrane microdomain that is formed at fungal entry sites and which comprises a subset of plant plasma membrane proteins. In the context of this project it is aimed to unravel whether this microdomain corresponds to 'lipid rafts' which are well-known in animal cells. In addition, the spatio-temporal interaction dynamics between MLO and SNARE proteins will be determined by using quantitative in vivo imaging techniques such as FRET, FCS and FCCS.

Executive Institute:

Max-Planck Institute for Plant Breeding Research (MPIZ) Details of Max-Planck Institute for Plant Breeding Research

Parent institution:

Max Planck Society for the Advancement of Science Details of Max Planck Society for the Advancement of Science (Bavaria)

Contract period:

01. 01. 2006 - 31. 12. 2010

Collaborative Project:

SFB 670: Cell-autonomous Immunity Details of SFB 670: Cell-autonomous Immunity

Funding Programme:

Subject:

  • Crop Protection

Purpose of research:

Basic research

Funding Institutions:

Project Management Agency: