SFB 670 TP10: Cell autonomous control of human papillomavirus infection
Description:
Human papillomaviruses (HPV) infect keratinocytes of skin and mucosa, where they induce benign or malignant proliferative lesions. Long term goal of this SFB project is to elucidate cell autonomous defence mechanisms of keratinocytes against HPV, and how the viruses cope with these defence mechanisms. This part of the project focusses on a novel mechanism activated by synthetic dsRNA (polyIC), which opens new therapeutic perspectives against HPV-disease, particularly for immunosuppressed patients.
Executive Institute:
Institute of Virology Details of Institute of Virology
Parent institution:
University of Cologne Details of University of Cologne (North Rhine-Westphalia)
Contract period:
01. 01. 2006 - 31. 12. 2010
Collaborative Project:
SFB 670: Cell-autonomous Immunity Details of SFB 670: Cell-autonomous Immunity
Funding Programme:
- DFG - Collaborative Research Centre Details of DFG - Collaborative Research Centre
Subject:
- Biotechnology
Purpose of research:
Basic research
Funding Institutions:
- German Research Council (DFG) (DFG) Details of (DFG)
Project Management Agency:
- German Research Council (DFG) (DFG) Details of DFG