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Projects of "5.16 Identification and evaluation of health risks associated with material properties of risks on cosmetic products, tattoo products, tobacco products, allergenic acting plants, plant products and consumer goods as well as development of strategies for r"   View in a table View in a table

2009: Development of a method suited to identify epigenetic effects in cells in culture upon exposure to low doses of model compounds, 2010: Investigation of epigenetic effects of consumer product-related model compounds in vitro - Details of 2009: Development of a method suited to identify epigenetic effects in cells in culture upon exposure to low doses of model compounds, 2010: Investigation of epigenetic effects of consumer product-related model compounds in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Analysis of the effects of developmental toxins from consumer products on microRNA (miRNA) expression during differentiation of embryonic stem cells. Identification of novel molecular endpoints and studies on the role of miRNAs in developmental toxicity - Details of Analysis of the effects of developmental toxins from consumer products on microRNA (miRNA) expression during differentiation of embryonic stem cells. Identification of novel molecular endpoints and studies on the role of miRNAs in developmental toxicity

Executive Institute: BfR - Department 9: Experimental Toxicology and ZEBET (BfR - TOX) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

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Cell cycle effects on the endocrine system and phase I metabolism - Details of Cell cycle effects on the endocrine system and phase I metabolism

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

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Characterization of cellular effects of contact sensitizers in vitro: Analysis of phosphotyrosine signaling pathways by far western blotting and establishment of a screening method - Details of Characterization of cellular effects of contact sensitizers in vitro: Analysis of phosphotyrosine signaling pathways by far western blotting and establishment of a screening method

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2010

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Characterization of metabolizing enzymes and biotransformation of selected test substances in human in-vitro skin models to identify an optimal test system for dermato-toxicological and exposure-related studies - Details of Characterization of metabolizing enzymes and biotransformation of selected test substances in human in-vitro skin models to identify an optimal test system for dermato-toxicological and exposure-related studies

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2011

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Chemical Imaging of Human Cells after Exposure to Metal Oxide Nanoparticles in vitro - Details of Chemical Imaging of Human Cells after Exposure to Metal Oxide Nanoparticles in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Description of the Nature of Accidental Misuse of Chemicals and Chemical Products (DeNaMiC) - Details of Description of the Nature of Accidental Misuse of Chemicals and Chemical Products (DeNaMiC)

Executive Institute: BfR – Department 3: Scientific Services (BfR - QUER) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2009

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Determination of di-iso-butylphthalate (DiBP) and di-n-butylphthalate (DnBP) in paper and board packagings for infant formulae and in the packaged food - Details of Determination of di-iso-butylphthalate (DiBP) and di-n-butylphthalate (DnBP) in paper and board packagings for infant formulae and in the packaged food

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

  • Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) Details of BMELV

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Development of a 'Contact Allergen Activated T-Cell (CAATC)-Assay' using dendritic cells from skin: characterization of the sensitizing potency of chemicals via dendritic cell-induced expression of lineage specific T cell transcription factors - Details of Development of a 'Contact Allergen Activated T-Cell (CAATC)-Assay' using dendritic cells from skin: characterization of the sensitizing potency of chemicals via dendritic cell-induced expression of lineage specific T cell transcription factors

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2010 - 2012

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Development of a contact allergen-induced T-cell assay using Langerhans cells: 2009: Expression of lineage specific T-cell transcription factors as biological endpoint suitable to indicate chemical induction of sensitization 2010: Measurement and quantification of transcription factors via qRT-PCR and FACS - Details of Development of a contact allergen-induced T-cell assay using Langerhans cells: 2009: Expression of lineage specific T-cell transcription factors as biological endpoint suitable to indicate chemical induction of sensitization 2010: Measurement and quantification of transcription factors via qRT-PCR and FACS

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Establishment and development of gentoxicity testing methods - Setup of the COMET assay for ingedients of product - Details of Establishment and development of gentoxicity testing methods - Setup of the COMET assay for ingedients of product

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

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Expert toxicological assessment of smoke constituents (ETASC) - Details of Expert toxicological assessment of smoke constituents (ETASC)

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2009

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Expression analysis of drug-metabolizing enzymes in human keratinocytes after treatment with selected xenobiotics - Details of Expression analysis of drug-metabolizing enzymes in human keratinocytes after treatment with selected xenobiotics

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Expression of xenobiotic metabolizing cytochrome P450 (CYP)-dependent monooxygenases in human keratinocytes and permanent skin cell cultures - Details of Expression of xenobiotic metabolizing cytochrome P450 (CYP)-dependent monooxygenases in human keratinocytes and permanent skin cell cultures

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

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Genotoxicity testing in 3D model ? Establishment and adaptation of the COMET assay using a model for bronchial epithelia exposed to ingredients of consumer products - Details of Genotoxicity testing in 3D model ? Establishment and adaptation of the COMET assay using a model for bronchial epithelia exposed to ingredients of consumer products

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

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Identification of novel molecular biomarkers enabling reliable assessment of endocrine distruptor activity in-vitro - Details of Identification of novel molecular biomarkers enabling reliable assessment of endocrine distruptor activity in-vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Impact of biofuels on the environmental and health effects of exhaust gas emissions from internal combustion engines - Details of Impact of biofuels on the environmental and health effects of exhaust gas emissions from internal combustion engines

Executive Institute: Institute of Agricultural Technology and Biosystems Engineering (TI-AT) Details of (Lower Saxony)

Parent institution: Johann Heinrich von Thünen-Institut - Federal Research Institute for Rural Areas, Forestry and Fisheries (TI) Details of TI

Contract period: 2001 - 2012

Funding Institutions:

  • Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) Details of BMELV

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Investigation of cytotoxicity and genotoxicity of water pipe smoke - Details of Investigation of cytotoxicity and genotoxicity of water pipe smoke

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2009

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Investigation on the skin penetration and skin toxicity of polycyclic aromatic hydrocarbons - Details of Investigation on the skin penetration and skin toxicity of polycyclic aromatic hydrocarbons

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2008 - 2008

Funding Institutions:

  • Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) Details of BMELV

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Metabolism of polyaromatic hydrocarbons by the microbiome of the skin - Details of Metabolism of polyaromatic hydrocarbons by the microbiome of the skin

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

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Mutagenicity and toxicity of water pipe smoke - Details of Mutagenicity and toxicity of water pipe smoke

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2006 - 2009

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On the evaluation of carcinogenic risks due to the exposure against dioxin-like and non-dioxin-like compounds - Details of On the evaluation of carcinogenic risks due to the exposure against dioxin-like and non-dioxin-like compounds

Executive Institute: BfR - Department 6: Chemicals Safety (BfR - CHS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2001 - 2008

Funding Institutions:

  • Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) Details of BMELV

Project Management Agency:

Proteomic analysis of cellular changes after treatment with contact allergens in human monocytic cell lines and in primary dendritic cells - Details of Proteomic analysis of cellular changes after treatment with contact allergens in human monocytic cell lines and in primary dendritic cells

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2011 - 2011

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Proteomic analysis of oxidative stress after nanoparticle treatment in cell culture to study cytotoxicity mechanisms - Details of Proteomic analysis of oxidative stress after nanoparticle treatment in cell culture to study cytotoxicity mechanisms

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Qualitative and quantitative analysis of toxicological relevant matters in the mainstream smoke of the waterpipe - Details of Qualitative and quantitative analysis of toxicological relevant matters in the mainstream smoke of the waterpipe

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2009 - 2010

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Screening assays for toxic and sensitizing substances in mixtures of azo dyes and its metabolites using human keratinocytes - Details of Screening assays for toxic and sensitizing substances in mixtures of azo dyes and its metabolites using human keratinocytes

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2007 - 2007

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Skin penetration in vitro - Details of Skin penetration in vitro

Executive Institute: BfR - Division 7: Safety of consumer products (BfR - PRS) Details of (Berlin)

Parent institution: Federal Institute for Risk Assessment (BfR) Details of BfR

Contract period: 2005 - 2008

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