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Serotype 4b variant (IVb-v1) of Listeria monocytogenes as source of an listeriosis outbreak in Germany

Project

Food and consumer protection

This project contributes to the research aim 'Food and consumer protection'. Which funding institutions are active for this aim? What are the sub-aims? Take a look:
Food and consumer protection


Project code: BfR-BIOS-08-1322-620
Contract period: 01.01.2015 - 31.12.2015
Purpose of research: Applied research

In 2010, Listeria monocytogenes (Lm) isolates of the serotype IVb-v1 were detected as source for a listeriosis outbreak in Germany. To date, IVb-v1 strains have been isolated only from sporadic human infections or food worldwide. Within this project, available outbreak isolates of serotype IVb-v1 were clustered in the population structure of Lm. We, therefore, typed a panel of 81 Lm isolates from a coordinated monitoring program on the prevalence of L. monocytogenes in ready-to-eat foods carried out in 2010 and 2011 in Germany using MLST. IVb-v1 isolates clustered with IVb and IIb isolates, but did not belong to a known clonal complex. Furthermore, isolates were typed by MiSeq sequencing. Sequencing data analysis has not yet been finalized due to failed de novo sequencing of a IVb-v1 isolate. The Genome diversity of IVb-v1 isolates taken from the outbreak and after persistence in the food producing plant as well as their epidemiological potential will be analyzed after de novo assembling of a representative IVb-v1 isolate as reference in the beginning of 2016.

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Subjects

Framework programme

BMEL Frameworkprogramme 2008

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