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FLI - Institute of Farm Animal Genetics (FLI - ING)
Institution
Section overview
Description
The Institute advises the national government on the topic of farm animal genetics. Research areas include animal breeding and animal genetics. The main research focus thus includes investigations into characterization and maintenance of genetic resources, the development of biotechnology related to animal breeding, and the development of information technology strategies for the management of genetic resources on a global scale. Characterization of genetic resources includes the determination of individual phenotypic variance – for example, in growth and reproduction - and thus makes it possible to analyze the productivity limits of economically important animals. The procedures of reproduction biology, such as in vitro production (IVP) of embryos, somatic cloning and stem cell technology represent an additional research focus. The combination of recent discoveries in molecular genetics with the latest reproduction technologies permits the production of transgenic animals for research and for the development of new procedures in biomedicine.
The Institute is also involved in research on molecular microbiology and antibiotic resistance which are impotant for the diagnosis and control of bacterial infections in farm animals.
Activities
- Research
Parent institution
Friedrich-Loeffler-Institute - Federal Research Institute for Animal Health (FLI)
Coordinated projects
- Characterization of emerging resistance mechanisms to β-lactam antibiotics (fluoro) quinolones in E. coli and S. enterica isolates from cattle and sick animals
- Collaborative project: development of tools for the assurance of genetic quality of breeding programmes(QA @ Breeding) - Subproject 1
- Collaborative project: Innovative ways of regional sustainable use of animal genetic resources in domestic chickens. Coordination
- Cryo-reserve in chicken
- Development and application of a new strategy for the estimation of the effective population size based on chromosomal segment homozygosity.
- Effects of xenobiotics on animal reproduction
- Fetal ontogeny of growth hormone and luteinizing hormone in the pig.
- Genome-wide characterization of sequence polymorphisms of functional traits related to bone stability in chicken layer lines differing in performance level
- Host-pathogen-interaction in E.coli resistance in chickens and its application to breeding prgrammes (E.coli-Chick)
- Innovative Management of Animal Genetic Resources
- Interactions of spermatozoa with leukocytes and epithelial cells in the uterus of cattle and pigs
- Investigation of gene expression in early embryos
- Reduction of Antibiotic Consumption in Pork Production by Integrating Epidemiologic Information from Consulting Expertise from Clinic, Hygiene, Microbiology and Pharmacology. Subproject 3
- Reprogramming of somatic cells and redifferentiation of embryonic cells
- Sex determination in pigs by CRISPR/Cas
- SYNBREED R2: Development of a SNP diversity panel in chicken
- To establish physiological indicators for improvement of sustainable animal production
- Transferable antimicrobial resistance among MRSA and MSSA from humans and animals
- Utilisation, conservation and evaluation of animal genetic resources and scientific support for the national Program on animal genetic resources in the context of the National Programme of Animal Genetic Resources.
Involved in research projects
- Basic research to influence the offspring sex in particularly endangered rhinoceros species
- Developing and testing a new approach for estimating the effective population size based on the homozygosity of chromosome segments
- EFabisnet - European Farm Animal Biodiversity Information System network
- Effects of exogenous equine parathyroid application (epth 1-37) on mineral homeostasis and bone in the horse
- GLOBALDIV - A global view of livestock biodiversity and conservation
- Interdisciplinary Research Network (MedVet-Staph) IP3 - MRSA in the food chain: Source attribution and transmission modelling based on molecularcharacterization of isolates from the food chain and from humans
- SYNBREED A3: Genomic Performance Prediction
- XENOME - Engineering of the porcine genome for xenotransplantation studies in primates: a step towards clinical application
Contact
FLI - Institute of Farm Animal Genetics
(FLI - ING)
Höltystraße 10
31535 Neustadt am Rübenberge
Lower Saxony
Germany
Phone: +49 5034 871 148
Fax: +49 5034 871 143
Email: heiner.niemann(@)fli.bund.de
