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Are you looking for a research project on animal health? Look at the subject animal production. Animal protection projects can be found in the research aim "environmental and resource protection"
Development of novel vaccine concepts against zoonotic pulmonary infections using the Venezuelan encephalitis equine virus replicon particle vaccine platform (OneHealth Vakzine - VRP)
Project
Project code: FLI-IfI-08-Ri-0780
Contract period: 01.07.2020
- 31.08.2021
Purpose of research: Experimental development
Zoonotic infections such as pulmonary tuberculosis cause chronic and deadly pathology in wildlife, livestock and humans. So far new vaccines against tuberculosis focus on single species solutions. However, in light of the WHO OneHealth concept, development of zoonotic vaccines against zoonotic infections should be of highest priority. Yet, investigations of the immunogenicity of the same vaccine against the same pathogen across different species are lacking. Therefore, this project focuses on systematically comparing the immune response to new zoonotic vaccines between different natural host species and experimental animal models. So far, such efforts were limited by the tools available to study the immune system in wildlife or livestock compared to studies in humans or small animal models. Single cell transcriptomics (scRNaseq) offers the opportunity to expand our tool set and knowledge of primary immune cells in understudied but relevant species in the context of zoonotic diseases. In this 1-year pilot project, we aim to compare the in vitro response of immune cells from mucosal sites and peripheral blood to different novel zoonotic vaccine concepts against tuberculosis across several mammalian species. At the same time, the goal is to gain insight into the characteristics of mucosal tissue immune cells across different species using systems comparative immunology.
Section overview
Subjects
- Animal health
Framework programme
Funding programme
Excutive institution
Funding institution
Project management agencies
Research projects by subject
| Subject | Ongoing Projects | Finished Projects | All Projects |
| sort | sort | sort | sort |
| Animal production | 266 | 3637 | 3903 |
| Ecology | 399 | 2935 | 3334 |
| Fisheries and Aquaculture | 95 | 509 | 604 |
| Food technology | 77 | 1963 | 2040 |
| Forestry | 59 | 1490 | 1549 |
| Interdisciplinary Subjects | 711 | 6975 | 7686 |
| Nutritional Science | 152 | 1412 | 1564 |
| Plant production | 685 | 6666 | 7351 |
| Socioeconomics | 61 | 1315 | 1376 |
A collaborative project describes a research plan of a researcher network. It includes several projects, work packages or subprojects. Coordination of the research areas and sub-projects is carried out by a research institution or a work package leader.
The subjects of agriculture and nutritional sciences in FISA are structured as follows:
Plant production
Crop Production, Plant Breeding, Plant Nutrition, Crop Protection, Agricultural Engineering in Plant Production, Grassland, Arboriculture, Horticulture, Vegetable Gardening, Viticulture, and Specialised crops.
Animal production
Animal breeding, Animal Husbandry, Agricultural Technology Animal Production, Animal health, Animal nutrition, Special animal species, Beekeeping and health, and Farm animal behaviour.
Fisheries and Aquaculture
Freshwater fisheries, Pond fisheries, Marine fisheries, Raceways systems, Recirculation systems, and Mariculture.
Forestry
Silviculture, Forestry, Wildlife Biology, Forestry Technology, and Forest genetics.
Ecology
Agricultural hydrology, Agricultural Meteorology, Agroecology, Landscape Planning, Soil science, and Organic Farming.
Socioeconomics
Agricultural Policy, Market Analysis, Business administration, Agricultural Sociology, Agroeconomics, and Rural history.
Nutritional Science
Physiology of Nutrition, Home Economics, Nutritional behaviour, and Toxicology.
Interdisciplinary Subjects
Process engineering, Communication Sciences, Biotechnology, Resource management, Genetic Resources, Renewable Resources, Climate Change, and Computer science.
Food technology
Food Chemistry, Food Processing, and Food microbiology.
