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Imprint
Competence Network PHENOMICS
Collaborative Project
Contract period:
01.02.2010
- 31.01.2015
Coordinating institution:
Institute for Farm Animals Science and Technology
PHENOMICS -
a system biological approach of genotype-phenotype-dinstinction in the context of farm animal performance, health and welfare in cattle and pig
Farm Animals provide an essential resource for the long-term production of high value food, which is tailored to suit the market needs. The growing population worldwide, the increasing prosperity in the newly industrialising countries and the change of food pattern will further increase the demand for products of animal origin. Up to now the perfomance of animal couldt be raised explicitly by directed breeding, though at the expense of health and welfare.
The future production of food of animal origin will stringently require the animal health as the leading concept, in which animal health and welfare demonstrate the link between the necessary connection of animal protection and sanitary consumer protection.
Here the farm animal specific network of competence PHÄNOMICS steps into the breach, which started in May 2010 and unites excellent competences of functional genome analysis, animal breeding and veterinary sciences, genetics of farm animals, biology of animal behaviour, animal husbandry, bioinformatics and biomathematics.
Collaborative Projects
Co-operative project 1 – Integrative Bioinformatics
Leading institution:
Leibniz Institute for Farm Animal Biology
Research projects
- Animal Trait Ontology\' – characteristics-ontology for the fields of behaviour and welfare and project database
- Bioinformatic pipeline to integrate high-efficiency-information and geno-/phenotypical parameters in network and PNFL system modells for cattle and hog
- Statistical analyses of associations between single nucleotide polymorphisms and gene expressions
- Derivative of biosignatures by utilisation of network-topological a-priori information and profiles of diverse levels of gene expression
Co-operative project 2 – Phenotyping of behaviour
Leading institution:
Leibniz Institute for Farm Animal Biology
Research projects
- Influencing factors of behavioural characteristics at hog
- Analyses of individual behavior pattern (disposition) at cattle
- AgroClustEr: a system biological approach of genotype-phenotype-distinction in the context of farm animal performance, health and welfare in cattle and pig - The PHENOMICS-office
Co-operative project 3 – Integration of “OMICS”–levels
Leading institution:
Gene Center Munich
Research projects
- Integrative OMICS-profiles for the definition of new phenotypes with relevance for the characteristic complexes metabolism and reproductive performance at cattle and hog
- Integrative OMICS-profiles of chosen relevant tissue of hog with different outputs of growth and constitution of flesh
- OMICS-profiles to derivate new selection criterions to reduce aggression and improve animal health at hog
- The OMICS-processes in medical diagnostics at cattle and hog
Co-operative project 4 – Validation of new phenotypes
Leading institution:
Leibniz Institute for Farm Animal Biology
Research projects
- Specification, qualification and validation of predictive parameters for value of money, health and welfare at hog
- Specification, qualification and validation of predictive biosignatures for milk yield and functional behavioural characteristics at cattle
- Characteristic association of biomarkers at diverse cattle and hog breed in different processes of production
- Characteristic association of biomarkers at diverse influences of feeding
- Gracilization and characteristic association of biomarkers under circumstances of pathogen infection
Co-operative project 5 – Implementation of new phenotypes
Leading institution:
Institute of Animal Breeding and Husbandry
Research projects
- Development of modified “genomic selection” modells
- Construction of a marker supported selection platform
- Process of optimal mate selection to use SNP-based estimations of non-additive gene effects
- Development of a multidimensional estimation system for animal justice with the help of the Multi-Criteria-Analyses (MCA)
- Validation of the developed Multi-Criteria-Analyse-system to optimise species-appropriate husbandry systems
