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Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances

Project

Food and consumer protection

This project contributes to the research aim 'Food and consumer protection'. Which funding institutions are active for this aim? What are the sub-aims? Take a look:
Food and consumer protection


Project code: BfR-ZEBET-08-1328-205
Contract period: 01.08.2007 - 31.07.2009
Purpose of research: Applied research

The aim of the project is to find a parameter as an indicator for the influence of test substances on cardiac function by calcium measurements in isolated cultured cardiomyocytes. Compared to other techniques, this should provide a meaningful method according to the guidelines for drug safety. At the same time this method has the potential to replace and reduce animal experiments.

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Subjects

Framework programme

BMEL Frameworkprogramme 2008

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