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Assessment of dermal absorption of pesticides (DA Assessment)
Project
Project code: BfR-PRS-08-1322-606
Contract period: 01.04.2015
- 31.12.2015
Purpose of research: Applied research
The extent of absorption of an active substance across the skin represents one of the major factors for the outcome of risk assessments for pesticides and biocides. Therefore, the dermal absorption is frequently influencing the decision about product approval and/or the choice of risk mitigation measures. At the same time, there are differences in the way the information on dermal absorption is interpreted by the competent authorities, causing deviating assessments. Although some guidance documents and guidelines are available on the issue, these leave room for interpretation, are conflicting in some cases and are not fully accepted by all. This project aims to improve the situation by addressing several of the open questions that have been collected from our risk assessment practice using a unique BfR Database. This database has been created 2010-2012 based on studies submitted for pesticide assessment until January 2011. The database will be updated with information from studies submitted 2011-2014 and extended by further parameters, namely physico-chemical parameters like solubility and formulation descriptors.
Section overview
Subjects
- Animal health
- Toxicology
- Computer science