Project code: BfR-CHS-08-1329-035
Contract period: 01.06.2001
Purpose of research: Basic research
Polyhalogenated dibenzo-p-dioxins or -furans as well as polyhalogenated biphenyls are cancerogenic when applied in animal experiments at higher doses. These compounds are widely distributed in the environment and in food in low concentrations. However they are always present as mixtures. It is planned to perform a tumor-promotion-experiment with mice, in which the effects are investigated when these compounds are applied separately and in combination. The results of the study should allow a better assessment of the exposure-related cancer-risks for humans.