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Information System for Agriculture and Food Research
Information platform of the Federal and State Governments
Projects of "6.7 Development and validation of alternative methods to animal testing "
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| Project code | Project | Start | End | Subject | Parent institution | Coordinating Institution | Funding Institutions | Project Management Agency | Project budget € |
|---|---|---|---|---|---|---|---|---|---|
| sort | sort | sort | sort | sort | sort | sort | sort | sort | sort |
| BfR-ZEBET-08-1342-448 | Best Search Practice on Animal Alternatives - A Guide for Untrained Database Users Details of Best Search Practice on Animal Alternatives - A Guide for Untrained Database Users | 2006 | 2011 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | EC | EC | 0.00 € |
| BfR-ZEBET-08-1328-177 | Computerised risk assessment of dermal absorption of active agents Details of Computerised risk assessment of dermal absorption of active agents | 2004 | 2008 | Food Chemistry | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-166 | Construction and Prevalidation of V79 Pathway Cell Lines: Heterologous Co-Expression of human Cytochrom P450 1A2 and polymorphic forms of human N-Acetyltransferase in V79 Chinese Hamster Cells for in vitro-studies on toxicity and metabolism of chemicals a Details of Construction and Prevalidation of V79 Pathway Cell Lines: Heterologous Co-Expression of human Cytochrom P450 1A2 and polymorphic forms of human N-Acetyltransferase in V79 Chinese Hamster Cells for in vitro-studies on toxicity and metabolism of chemicals a | 2001 | 2004 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-203 | Development and evaluation of alternative methods to replace animal experiments (NIH-Test) for the potency measure of vaccines against rabies Details of Development and evaluation of alternative methods to replace animal experiments (NIH-Test) for the potency measure of vaccines against rabies | 2007 | 2010 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1334-192 | Development of a biotransformation system for the metabolic activation of validated in vitro systems to study embryotoxicity Details of Development of a biotransformation system for the metabolic activation of validated in vitro systems to study embryotoxicity | 2008 | 2011 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BMBF | BMBF | 0.00 € |
| BfR-ZEBET-08-1328-205 | Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances Details of Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances | 2007 | 2009 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-183 | Development of bioreactors for in vitro testing of biological heart valves for reduction of animal experiments Details of Development of bioreactors for in vitro testing of biological heart valves for reduction of animal experiments | 2004 | 2006 | Food Chemistry | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1334-176 | Development of Predictive In Vitro Test for Developmental Neurotoxicity testing Details of Development of Predictive In Vitro Test for Developmental Neurotoxicity testing | 2007 | 2011 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1342-465 | Embryonic stem cell-based novel alternative testing strategies (ESNATS) Details of Embryonic stem cell-based novel alternative testing strategies (ESNATS) | 2008 | 2013 | Animal health, Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | EC | EC | 0.00 € |
| BfR-ZEBET-08-1328-204 | Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets Details of Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets | 2007 | 2008 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-208 | Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals Details of Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals | 2007 | 2010 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-192 | Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures Details of Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures | 2006 | 2009 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-190 | Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies Details of Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies | 2005 | 2008 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-174 | HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study Details of HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study | 2004 | 2008 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1322-295 | Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro Details of Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro | 2004 | 2010 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-191 | Improving the gain of transgenic mouse embryos for cryopreservation Details of Improving the gain of transgenic mouse embryos for cryopreservation | 2005 | 2006 | Special animal species, Genetic Resources | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-182 | In vitro exposure of lung cells with aerosol at the air-liquid-layer as an alternative for inhalation experiments with animals Details of In vitro exposure of lung cells with aerosol at the air-liquid-layer as an alternative for inhalation experiments with animals | 2004 | 2007 | Food Chemistry | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1334-168 | Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials Details of Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials | 2004 | 2007 | Special animal species, Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BMBF | BMBF | 0.00 € |
| BfR-ZEBET-08-1334-183 | Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays Details of Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays | 2009 | 2010 | Animal health, Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BMBF | BMBF | 0.00 € |
| BfR-ZEBET-08-1328-178 | Normal human neural progenitorcells as a screening model for substances that are toxic for neural development. Details of Normal human neural progenitorcells as a screening model for substances that are toxic for neural development. | 2004 | 2007 | Physiology of Nutrition, Food Chemistry, Food microbiology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-02-1328-181 | Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models Details of Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models | 2004 | 2006 | Food Chemistry, Food Processing, Biotechnology, Food microbiology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-206 | Preparation for external prevalidation: Optimization of the internally validated and standardized method for quantitation of angiogenesis and antiangiogenesis in vitro by determination of the angiogenic standard of the cells to be used Details of Preparation for external prevalidation: Optimization of the internally validated and standardized method for quantitation of angiogenesis and antiangiogenesis in vitro by determination of the angiogenic standard of the cells to be used | 2007 | 2010 | Animal health, Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-202 | Refinement of the LCSA (loose-fit coculture-based sensitization assay) Details of Refinement of the LCSA (loose-fit coculture-based sensitization assay) | 2007 | 2008 | Biotechnology | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |
| BfR-ZEBET-08-1328-407 | Replacement of transgenic animal models for determination of in vivo mutations by refinement of regulatory animal studies with the technique of the Random Mutations Capture Assay Details of Replacement of transgenic animal models for determination of in vivo mutations by refinement of regulatory animal studies with the technique of the Random Mutations Capture Assay | 2009 | 2011 | Animal breeding | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BMELV | BMELV | 0.00 € |
| BfR-ZEBET-08-1328-209 | Studies on the anti-oxidative responses of lung cells as an endpoint for the assessment of aerosols after exposure at the air-liquid interface Details of Studies on the anti-oxidative responses of lung cells as an endpoint for the assessment of aerosols after exposure at the air-liquid interface | 2007 | 2011 | Animal health | Federal Institute for Risk Assessment (BfR) Details of Federal Institute for Risk Assessment (BfR) | BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) Details of BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments (BfR - ZEBET) | BfR | BfR | 0.00 € |