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Relevancy: 100%
Reporter gene assays in permanent cell lines as screening tools for the detection of food contaminants (Project)
The detection of food contaminants such as dioxins, mycotoxins, pesticides or perfluorinated compounds with classical analytical methods is expensive and time-consuming. The con-cept of effect-based analytics is based on the detection of biological effects induced by the substances or substance class mentioned above. In many cases, these biological test sys-tems are not as expensive as chemical...
Funding period: 2010 - 2011
Relevancy: 100%
Proteomic analysis into molecular toxicological effects of nano particles in human intestinal Caco-2 cells (Project)
Also in food stuff, nanotechnologies and associated manufactured nano particles are in-creasingly used. It is estimated that more than 90 different materials in more than 600 differ-ent food products are presently used. Since health risks of nanoparticles in food stuff are not yet scientifically proven and presence of nanomaterial in food stuff cannot be monitored rou-tinely, labelling of...
Funding period: 2010 - 2011
Relevancy: 100%
Proteomic analysis of effects induced by 3-MCPD and 3-MCPD fatty acid esters in rat liver and kidney (Project)
The thermal treatment of fat-containing foodstuff in the presence of salt leads to the formation of 3-MCPD (3-monochloropropane-1,2-diol) fatty acid esters. Surprisingly high concentrations of 3-MCPD esters were detected in refined vegetable oils and fats and in milk powder used for the nutrition of infants. Upon hydrolytic cleavage, these substances are me-tabolized to 3-MCPD, which may lead to...
Funding period: 2010 - 2011
Relevancy: 100%
Influence of endocrine disruptors using the example of soy isoflavones on the transformationof multipotent progenitor cells of the human mammary epithelium (Project)
Isolated isoflavones are currently components of dietary supplements, marketed to womennear or after menopause, to treat postmenopausal symptoms. However, the epidemiologicaldata to the effect of isoflavone intake on breast cancer is contradictory. According to the stemcell theory of carcinogenesis, breast stem cells are the roots of breast cancer, and are thusthe ideal target for the proposed...
Funding period: 2010 - 2011
Relevancy: 100%
Development of a hepatic in vitro test system for the sensitive detection of pyrrolizidine alka-loids (Project)
Unsaturated pyrrolizidine alkaloids (PA) belong to the most toxic compounds; more than 400 PAs have been described in a wide range of plants. They are also found in Senecio vulgaris L. PAs are toxic to humans and animals. Acute PA poisoning via food contamination causes severe damage to the liver; long-term, sub-lethal doses may cause cumulative damage or cancer. Animal studies revealed that PA...
Funding period: 2010 - 2011
Relevancy: 100%
Determination of pyrrolizidine alkaloids in food and feed (Start-up funding of a research project BMELV) (Project)
The term pyrrolizidine alkaloids (PA) describes a group of more than 350 different com-pounds with a common basic structure. PA are produced as secondary metabolites by more than 6000 plant species belonging to the families of Boraginaceae, Compositae (As-teraceae) and Leguminosae (Fabaceae). PA occur world-wide.Basic alkaloids seem to accumulate in the seeds, whereas the respective N-oxides...
Funding period: 2010 - 2011
Relevancy: 100%
Nutrient-controlled slurry application (Project)
Specific proposal for a targeted use of manure is still missing the ability to directly measure the ingredients and then being able to control the application on the basis of levels of nutrients. In this project, therefore, the practical testing of a method for planting and environmentally sound application of manure and biogas digester substrates sought. What is new is that a flow-infrared...
Funding period: 2006 - 2009
Relevancy: 100%
New knowledge for organic working farmers - events for knowledge transfer (Project)
The aim of holding the events of the project is that producers, traders and processors better than ever on advances in knowledge about organic farming tic items and the transfer of knowledge, the variety and encourage with great effort compiled results of research on organic farming, and to continue. These events will take place nationwide on knowledge transfer. To achieve this, emphasis will be...
Funding period: 2010 - 2012
Relevancy: 100%
New knowledge for organic working farmers - events for knowledge transfer (Project)
Target for the implementation of the events of the project is to allow its producers, traders and processors more on advances in knowledge about organic farming and the transfer of knowledge of the diverse and transported at great expense compiled results of research on organic farming and continue. These events will take place nationwide on knowledge transfer. To achieve this, emphasis will be...
Funding period: 2011 - 2011
Relevancy: 100%
New knowledge for organic working farmers - events for knowledge transfer (Project)
Target for the implementation of the events of the project is to allow its producers, traders and processors more on advances in knowledge about organic farming and the transfer of knowledge of the diverse and transported at great expense compiled results of research on organic farming and continue. These events will take place nationwide on knowledge transfer. To achieve this, emphasis will be...
Funding period: 2011 - 2011
