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Relevancy: 100%
Establishment of a long-term 3D in vitro niche model for investigating myeloid neoplasms (Project)
The main objective of the planned work is to create a long-term culture system in which patient-specific hematopoietic cells grow in a bone marrow niche. To this end, a state-of-the-art standardized, universal, reliable and robust in vitro-optimized perfusion bioreactor for primarily malignant human 3D bone marrow models will first be developed. In this reactor, bone marrow niche components such...
Funding period: 2024 - 2027
Relevancy: 100%
Improving detection of quarantine rust fungi (Project)
The main goal of this Euphresco project is to pave the way to a more streamlined diagnostic process for quarantine rust fungi and facilitate the development of robust diagnostic methods. There are three main objectives for this project: 1. Building an accessible collection of rust fungi that occur in Europe including species that are closely related to quarantine species and consisting of:...
Funding period: 2024 - 2027
Relevancy: 100%
Humboldt CAPES-Fellowship - Liver toxicity and non-animal methods (New Approach Methods) in connection with the combination effects of pesticides (Project)
Microcystins (MCs) are a group of cyclic peptide toxins produced by cyanobacteria well recognized as food and water contaminants and nowadays pose concerns as potential metabolic by-products of certain types of biological pesticides. There are approximately 286 MCs already characterized, yet less than 10% have their toxicological profiles determined. Among these, the MC-leucine arginine (MC-LR)...
Funding period: 2024 - 2027
Relevancy: 100%
Co-creating a blueprint of a harmonised European Forest Multifunctionality Monitoring System (Project)
currently unavailable
Funding period: 2024 - 2027
Relevancy: 100%
Establishment of a standardized microfluidic 3D-bioprinting apporach for the preclinical therapy of highly malignant tumors (Project)
The long-term goal is to establish a standardized preclinical in vitro model for the prediction of therapy response in glioblastomas and head-neck-tumors. For this purpose, patient-specific 2D and 3D spheroid and organoid models of primary tumor samples were established in advance. Using these tumor models, two common 3D bioprinting methods are comparatively analyzed in the first subproject and...
Funding period: 2024 - 2026
Relevancy: 100%
Health risks of synthetic cannabinoids (Project)
The aim of the project is to improve the data situation with regard to the health risks posed by synthetic cannabinoids in products that fall within the BfR's area of responsibility. This includes, for example, smoking mixtures made from herbs, so-called incense sticks or room air fresheners and e-liquids for e-cigarettes/vaporisers, but also products that can be perceived as food (including...
Funding period: 2024 - 2024
Relevancy: 100%
Impairment of phloem function, a key event in phytoplasma pathogenicity: Apple proliferation disease as a case study (Project)
currently unavailable
Funding period: 2016 - 2025
Relevancy: 100%
Biodiversity Exploratories (functional biodiversity research) - Determination of residues of active substances from plant protection products and biocides in soil and plant samples from grassland and forest sites. (Project)
Fortification experiments with soil and plants were carried out at the Institute for Bee Protection in order to validate the range of active ingredients agreed with the project partners using the established multi-method. In addition, a further multi-method (QuEChERS) had to be tested, established and validated to determine the herbicides relevant to the project questions.
Funding period: 2021 - 2023
Relevancy: 100%
Effect of inhibited ammonium sulphate urea on the increase of the nitrogen use efficiency and reduction of ammonia and nitrous oxide emissions due to mineral fertilization (Project)
currentl unavailable
Funding period: 2021 - 2024
Relevancy: 100%
Pixel-specific parametrization of models to derive crop state variables from hyperspectral data and yield estimates (Hy-PiPE) (Project)
The crop-specific parameterization of PROSAIL-PRO can be realized by creating pixel-based feature classes. In addition to the preparation of spatial data (soil, weather/climate, topography), the integration of Germany-wide products for the classification of agricultural crop types and the development of a spatial hyperspectral soil data set are used for this purpose. EnMAP data serve as a basis...
Funding period: 2022 - 2025
