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Relevancy: 58%

GHG mitigation trough model based optimisaiton and evaluation of cropping systems for renewable ressources. (Project)

...The focus of this project is on the three relevant components of GHG assessment: yield (potential GHG savings), direct N2O emissions and nitrate leaching as the basis for indirect N2O emissions. ...The overall project is divided into 9 work packages, which are to be tackled in close cooperation between the project partners Christian-Albrechts-University Kiel and Thünen-Institut Braunschweig. Specifically, the following APs are defined: AP1 - project coordination, AP2 - preparation of experimental data for model calibration and evaluation, AP3 - calibration and evaluation of models for estimating productivity, direct nitrous oxide emissions and nitrate leaching of cropping systems, AP4 calculation of GHG indicators for the data sets of the AP2, AP5 analysis of soil and climatic effects on GHG indicators, AP6 - Comparative assessment of applicability of models, AP7 - Model-based optimization of cropping systems, AP8 - Meta models for forecasting of N leaching in NaWaRo systems and AP9: Stakeholder workshops...


Funding period: 2019 - 2021

Relevancy: 58%

Collaborative project: GHG mitigation through model based optimisaiton and evaluation of cropping systems for renewable ressources (Project)

...The focus of this project is on the three relevant components of GHG assessment: yield (potential GHG savings), direct N2O emissions and nitrate leaching as the basis for indirect N2O emissions. ...The overall project is divided into 9 work packages, which are to be tackled in close cooperation between the project partners Christian-Albrechts-University Kiel and Thünen-Institut Braunschweig. Specifically, the following APs are defined: AP1 - project coordination, AP2 - preparation of experimental data for model calibration and evaluation, AP3 - calibration and evaluation of models for estimating productivity, direct nitrous oxide emissions and nitrate leaching of cropping systems, AP4 calculation of GHG indicators for the data sets of the AP2, AP5 analysis of soil and climatic effects on GHG indicators, AP6 - Comparative assessment of applicability of models, AP7 - Model-based optimization of cropping systems, AP8 - Meta models for forecasting of N leaching in NaWaRo systems and AP9: Stakeholder workshops...


Funding period: 2019 - 2021

Relevancy: 58%

Interaction between metabolism and transport of toxicologically relevant compounds in the gastrointestinal barrier (Project)

...Intestinal resorption of cancerogenic contaminants of food such as the polycyclic aromatic hydrocarbon (PAHs) benzo[a]pyrene (B[a]P) is affected by the interaction of CYP1A1/CYP1B1, phase II XMEs and ABC-transport proteins. ...During the first phase of this project we studied the mechanism of detoxification of the ultimate carcinogenic phase I B[a]P metabolite anti-B[a]P-7,8-diol-9,10-epoxide (BPDE). Formation of glutathione (GSH) conjugates mediated by glutathione-S-transferases (GSTs) as well as the excretion of these conjugates was analysed. ...It will comprise a) the influence of the flavonol quercetin, b) the role of the BCRP (use of the bcrp-/- knockout mice) as well as c) the role of MRP2/3 using the mrp2/3 double knockout mice....


Funding period: 2010 - 2013

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 1 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values....


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 2 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values....


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 3 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values.  ...


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 4 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values....


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 5 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values.  ...


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 6 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values....


Funding period: 2012 - 2016

Relevancy: 57%

Collaborative project: Strategies to avoid boar taint during fattening of entire male piglets - subproject 7 (Project)

...Therefore 775 performance tested intact boars (Pi x F1) as well as the purebred sires (Pi) were genotyped with the SNP60 Illumina Bead Chip and phenotyped. ...Accuracies ranged between 0,65 and 0,70. In order to verify the gs-breeding values 162 AI-sires were mated with crossbred dams. 2946 intact boars were fattened and phenotyped for boar taint. Calculated heritabilities were on a high level (h2: 0,4-0,6). Furthermore it could be shown that the frequency of tainted carcasses can be reduced significantly by the selection of boars based on gs-breeding values....


Funding period: 2012 - 2016