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Relevancy: 100%
HC-Pro as a tool to study silencing suppressor-mediated induction of disease symptoms in plants (Project)
It is important to understand the mechanisms of symptom development in response to virus infection to design new strategies to produce virus resistant plants. In general, symptoms induced by potyviruses are based on the cellular effects of one of their proteins, the helper-component proteinase (HC-Pro). In plants, the HC-Pro interferes with small RNA metabolism and function, and such interference...
Funding period: 2007 - 2010
Relevancy: 100%
Science-to-Business-Center AgroHort (Project)
no details
Funding period: 2009 - 2012
Relevancy: 100%
Towards safe applications of recycled water in agriculture: Effects of soil properties on the survival of wastewater bacteria and their potential to colonize vegetables (Project)
The objective of this bilateral project with Israel is to gather information on the capacity of bacteria from treated wastewater (TWW) to survive in different types of soil and to colonize vegetables through the rhizosphere. The data will be helpful for risk managers to apply a site-optimized irrigation regime for the production of safe vegetables. (1) Quantitative detection of pathogens and...
Funding period: 2014 - 2017
Relevancy: 100%
Carbon and nutrient storage of forest sites within the forest monitoring networks of Rhineland-Palatinate (BZE, Level II) (Project)
Assessment of biomass and element storage in tree layers, in the understorey and in forest soils of 165 sites of the national soil survey (BZE) and 6 sites of the intensive forest monitoring in Rhineland-Palatinate. Derivation of general evaluation methods and pattern of element storage that are valid for forest monitoring sites across Germany.
Funding period: 2010 - 2011
Relevancy: 100%
SFB 670 TP1: The professional phagocyte Dictyostelium as a host model for pathogens (Project)
To be able to cope with potential pathogens most organisms have developed elaborate defense mechanisms. They often harbor specialized cells that have the ability to rapidly and efficiently internalize a variety of organisms and particles and degrade them. Macrophages, myeloid dendritic cells, neutrophils represent professional phagocytes that are important for innate and adaptive im-munity. We...
Funding period: 2006 - 2010
Relevancy: 100%
SFB 670 TP2: Molecular mechanisms of host cell entry by phytopathogenic powdery mildew fungi via suppression of cell-autonomous plant defence (Project)
Isoforms of plasma membrane-localized MLO and SNARE proteins are plant polypeptides involved in the regulation of host cell entry by phytopathogenic powdery mildew fungi. MLO and t-SNAREs (syntaxins) interact with each other and are part of a plasma membrane microdomain that is formed at fungal entry sites and which comprises a subset of plant plasma membrane proteins. In the context of this...
Funding period: 2006 - 2010
Relevancy: 100%
Molecular analysis of the interaction between pathogenic Rhodococcus equi and their host macrophages (Project)
Mikroorganisms that reach the sterile sections of higher organisms are usually quickly ingested by phagocytes (e.g., macrophages), are killed and degraded. Some specialised pathogens, e.g., bacteria of the species Rhodococcus equi can, however, reprogram the defense apparatus soon after their ingestion, so that they are not confronted with the killing and degradation machinery of the macrophage....
Funding period: 2006 - 2010
Relevancy: 100%
SFB 670 TP4: Role of sphingomyelinase for the membrane-bound antibacterial effector mechanisms (Project)
Recruitment of antimicrobial enzymes to the phagosome via vesicular transport processes essentially contributes to the regulation of oxidative and non-oxidative antibacterial mechanisms. We have previously shown the importance of acid Sphingomyelinase (ASMase) for the control of intra-cellular bacteria. In this project we aim at characterizing the molecular mechanisms by which the lipid-modifying...
Funding period: 2006 - 2010
Relevancy: 100%
SFB 670 TP5: Characterization and modulation of the Osteoblasts-specific Staphylococcus aureus phagosome (Project)
As the most frequent cause of chronic osteomyelitis, S. aureus is able to infect osteoblasts and to persist inside a specific intracellular phagosomal compartment. The aim of this project is the characterization of the osteoblast-specific phagosome, which is the key to the development of persistence. The maturation state and the kinetics of formation of the S. aureus-containing phagosome will be...
Funding period: 2006 - 2010
Relevancy: 100%
SFB 670 TP6: Role of p47 (IRG) GTPases in cell-autonomous resistance to protozoal pathogens (Project)
The interferon-inducible p47 (IRG) GTPases are major effectors of cell-autonomous immunity in mice against vacuolar pathogens. Little is known about their mechanism of action. We have proposed that the action of the p47 GTPases in Toxoplasma immunity is mediated through the vesiculation and ultimately the destruction of the parasitophorous vacuole membrane. Our work is designed to examine this...
Funding period: 2006 - 2010
