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Search for: fh62VKoX2FU0lEOwkF43GA7tzz7cUk55eQG9OuEGpGyuFcwfwqofu1SOH9bhwXJO, 10 of 8070 ResultsSorting
Relevancy: 47%
Improving the health quality of food by increasing and modifying the carotenoid content (Project)
...Garcia AL, Mohan R, Koebnick C, Bub A, Heuer T, Strassner C, Groeneveld MJ, Katz N, Elmadfa I, Leitzmann C, Hoffmann I (2009) Plasma beta-carotene is not a suitable biomarker of fruit and vegetable intake in German subjects following a long-term high consumption of fruits and vegetable. ...Br J Nutr Nov 20:1-9 (Epub ahead of print)Ralph Rühl, Achim Bub, Bernhard Watzl (2008) Modulation of plasma all-trans-retinoic acid concentrations by the consumption of carotenoid-rich vegetables. ...Eur J Nutr 47(2): 99-103.Schnäbele K, Briviba K, Bub A, Pool-Zobel B-L, and G Rechkemmer (2008) Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans. ...
Funding period: 2001 - 2004
Relevancy: 46%
Identification of genetic factors influencing replant disease in apple (Project)
...The aim of the 2nd phase of Ordiamur-project is to elucidate the genetic mechanisms for susceptibility and tolerance of apple plants to the Apple Replant Disease (ARD). ...Until date, only a few Malus genotypes have been described as tolerant to ARD and less in known about the genetic mechanisms underlying the tolerance of Malus genotypes to ARD. Within the project (1) the genetic map established in Phase I should be replenished and saturated by genotyping-by-sequencing (GBS) in order to create a high-resolution map for the mapping population M9 x M. × robusta 5. (2) Moreover, the phenotypic data of the mapping population from phase I should be ensured due to two further greenhouse experiments. ...The first system is a virus-induced silencing method; the second system is to be based on CRISPR/Cas9....
Funding period: 2019 - 2021
Relevancy: 46%
Reasons for culling sows - instrument to improve herd management (Project)
...The new recording system had 9 main chapters with about 90 single points. Besides the main reason farmers could use up to 3 sub-reasons. 46 pig-farms in North Rhine Westphalia with about 10.000 sows (average was 210 sows per farm) used a new code-system of culling reasons. Nearly 2.500 sows were recorded. On average 92 % were slaughtered, 6 % of them were found dead, 2 % were euthanized. The farms differed extremely from 0 to 17 % of mortality or euthanizing-rate. More than the half of the records had at least one sub-reason. ...
Funding period: 2007 - 2008
Relevancy: 46%
Calcium signals and associated genes (Project)
...We will identify candidate genes for upstream and downstream components of the Ca2+ signal (i.e. Ca2+ channels, transporters, and sensor proteins) by bioinformatics analysis supported by project B7 of the C. graminicola genome sequence traces. ...To identify individual Ca2+ signals in the C. graminicola infection process, the fungus has been transformed with the novel codon-optimized Ca2+ reporter protein aequorinS. Using luminometry and photon imaging, we will determine at what stages and in which cell types Ca2+ signals occur (e.g., spore germination, appressorium formation, switch from biotrophy to necrotrophy), as well as the kinetics of the Ca2+ transients. ...
Funding period: 2006 - 2010
Relevancy: 46%
Use of mobile CRISPR/Cas9 transcripts to produce transgene free mutants in one generation by grafting (Project)
...Use of CRISPR/Cas9 is based on the production of transgenic plants expressing a sequence specific guide RNA (gRNA) and the Cas9 nuclease, which obviously does not meet the standards of having stable plant lines that are used in agriculture. ...In grafted plants mobile CRISPR gRNA and Cas9 transcripts can introduce targeted mutations in the wild-type scion plant parts forming flowers. ...By using this approach - mobile CRIS/Ccas9 transcripts combined with grafting - we can produce transgene free mutants within one generation. ...
Funding period: 2018 - 2020
Relevancy: 46%
Exposure pathways for lead in the human organism (Project)
...Available from: https://www.umweltprobenbank.de/de/documents/selected_results/12700. 2. Apostolou A, Garcia-Esquinas E, Fadrowski JJ, McLain P, Weaver VM, Navas-Acien A. ...Pascale A, Sosa A, Bares C, Battocletti A, Moll MJ, Pose D, et al. E-waste informal recycling: An emerging source of lead exposure in South America. ...Environ Res. 2007;103(1):30–7. doi: 10.1016/j.envres.2006.05.009....
Funding period: 2018 - 2019
Relevancy: 45%
Genomics-based exploitation of wheat genetic resources for plant breeding (Project)
...The overall goal of GeneBank2.0 is to leverage the wheat ex-situ collection hosted at the IPK Gatersleben to an actively deployed one in plant breeding by applying an integrated concept encompassing cutting-edge genomics, phenomics, biodiversity informatics, and precision (pre)breeding. The goal is to characterize the winter wheat ex-situ collection (ca. 9,700 accessions) of the IPK Gatersleben to identify novel resistances which are not present in wheat elite cultivars. ...
Funding period: 2019 - 2022
Relevancy: 45%
Molecular mechanisms of furan-mediated liver toxicity (Project)
...Direct genotoxicity is presumably due to the oxidation of furan to the mutagenic substance cis-2-butene-1,4-dial mediated by the liver enzyme Cyp2E1. However, additional cytotoxic, Cyp2E1-independent effects of furan are discussed, the mechanisms of which are largely unknown so far. ...The study focuses on the identification of Cyp2E1-independent signalling and metabolic pathways addressed by furan. ...
Funding period: 2009 - 2009
Relevancy: 45%
Determination of 2-and 3-MCPD-fatty acids esters in human milk (Project)
...Free 3-monochloropropane-1,2-diol (3-MCPD) has been known as a contaminant for a long time in various foods like liquid seasoning or bakery goods. ...Since the fat component of infant formula is based on the use of refined vegetable oil, the exposure of formula-fed infants is notably high (median concentration can lead to a 7.7-fold exceeding of the TDI, assuming that esters are fully hydrolyzed) [1]. Considerable amounts of 3-MCPD-esters in human milk have been detected by Zélinková et al. in 2008 [2]. Considering the average 3-MCPD content of 35.5 µg/kg milk, the daily intake of 3-MCPD of an exclusively breast-fed baby is 2.8 times higher than that corresponding to TDI. ...
Funding period: 2011 - 2011
Relevancy: 45%
Food borne pathogenes: Behavior of pathogenic bacteria in food of animal origin, measures to minimize risks including the hurdle concept for safe foods (Project)
...Study of the growth behavior of pathogenic bacteria in food of animal origin, e.g. raw sausages, in order to minimize risks by various measures based among others on the hurdle technology. ...Acidified nitrite inhibits proliferation of Listeria monocytogenes — Transcriptional analysis of a preservation method; International Journal of Food Microbiology, 226, 33–41Vorträge und Poster Böhnlein, C. Verhalten von EHEC-Ausbruchsisolaten in Rohwurst: E. coli O157:H7 vs. E. coli O104:H4. Institutskolloquium Ernährungs- und Lebensmittelwissenschaften, CAU Kiel, 09.11.2015.Böhnlein, C.; Kabisch, J.; Pichner, R. ...
Funding period: 2001 - 2021
