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Search for: fh62VKoX2FU0lEOwkF43GA7tzz7cUk55eQG9OuEGpGyuFcwfwqofu1SOH9bhwXJO, 10 of 8024 ResultsSorting
Relevancy: 50%
Pesticide Use-and-risk Reduction in European farming systems with Integrated Pest Management (Project)
...WP1.6 IPM solutions to reduce pesticides reliance in grapevine T1.6.1: Identification of alternatives to pesticides, models and design of IPM candidate solutions with stakeholders T1.6.2: Ex-ante assessment including stakeholders’ input T1.6.3a: On-station experimentation of candidate IPM Solutions V5.7 PURE 26/205 CONFIDENTIAL T1.6.3b: On-farm test of IPM solutions and dialogue with stakeholders T1.6.4: Ex-post assessment including Stakeholders’ input...
Funding period: 2011 - 2015
Relevancy: 50%
Role of OCT4 during preimplantation development of bovine embryos (Project)
...Differences include the interaction of OCT4 and CDX2 in the trophectoderm as well as the role of FGF/MAPK signaling during the second lineage differentiation of the hypoblast. ...Our work program will include immunofluorescence on markers specific to the cell lineages in the early embryo, i.e. GATA6 for hypoblast, NANOG for epiblast and CDX2 for trophectoderm, and transcriptome analysis by RNA sequencing. To confirm findings from embryos produced via SCNT, we want to produce OCT4 KO embryos through direct injection of CRISPR/Cas9 into in vitro fertilized zygotes. Additionally, we aim to elucidate the second lineage differentiation and the role of OCT4 during by transfer of embryos to recipient cows at day 7 and their recovery at day 12. ...
Funding period: 2018 - 2020
Relevancy: 49%
Elaboration of a report concerning the infestation situation and control of the European corn borer (Ostrinia nubilialis) and the Western corn rootworm (Diabrotica virgifera virgifera) in Europe and particularly in Germany (Project)
...Because a systematic monitoring on European corn borer does not exist, the infestation level either assessed or estimated was documented using five infestation intensity groups (0: no occurrence, X: low infestation - 50% infested steams). ...The area of chemical and biological control was estimated at slightly more than 40,000ha (2% of maize growing area) and 27,000ha, respectively, in 2013. ...The Western corn root worm borer was determined in 34 counties (7% of all counties) by 2013. While chemical control measures were performed on 2,432ha in the year 2009, two years after the first record of pest in Germany, the insecticide use reduced to 192ha und even only 9ha in the years 2012 and 2013, respectively. ...
Funding period: 2013 - 2014
Relevancy: 49%
HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study (Project)
...A positive correlation (without digoxin) of r²= 0.81 between IC50 values on HPCT-1E3 cells and human LD50 values from the MEIC study was observed for twenty cytotoxic drugs. The correlation between LD50 values from human and rat accounts for 0.54 corresponding to the MEIC study. For the IC50 values of toxic substances which are transported by carriers a correlation of 0.975 to data from HepG2 cells was estimated. In conclusion, HPCT-1E3 cells are a good model for studying cytotoxicity and comparable to HepG2 cells in terms of acquisition of pharmacokinetic interactions of drugs which are transported by carriers....
Funding period: 2004 - 2008
Relevancy: 49%
Bat influenza virus chimeras as basis for the development of a new type of vaccine backbone for live stock vaccination (Project)
...This is mainly due to the risk of reassortment events between vaccine strains and wild type IAV-strains, and partly to the pathogenicity associated with vaccine strains e.g. in very young animals. However, we recently succeeded to generate chimeric viruses containing six out of the eight bat H17N10 virus genes, with the remaining two genes encoding the haemagglutinin (HA) and neuraminidase (NA) proteins of a prototypic influenza A virus (IAV). ...We also want to equip these viruses with HA and NA of high (H5, H7) and low (H1, H5, H7, H9) pathogenic avian IAV and determine the growth properties and associated immune responses in chicken. ...
Funding period: 2016 - 2019
Relevancy: 49%
Investigation on contamination of raw consumed food of vegetable origin with VTEC / STEC / EHEC using serological and molecular detection methods (Project)
...On VRBD agar for detection of Enterobacteriaceae bacterial counts were determined between 105 to larger than 106 cfu per gram. The benchmark for E. coli (1x102 CFU / g) was exceeded in 5 samples, but not the warning value of 1x103 CFU / g. ...Using real-time PCR the genes for Shiga toxins (stx genes) were detected in 2 (5.0%) and for other virulence markers of EHEC, such as intimin (eae), in one (2.5%) sample. ...Due to the high numbers of other bacteria that are initially present, even after enrichment 1,000 fold higher amounts of other Enterobacteriaceae are found, compared to E. coli. ...
Funding period: 2009 - 2010
Relevancy: 49%
SFB 564: C2.2 - Rehabilitation of barren hills: Improvement of communal grazing lands (Project)
...This work has only begun in 2002 and will continue, within the proposed 2nd-phase research, until 2005. Research results of the first SFB phase (subprojects C2 and F1) suggest that a considerable portion of barren hills is used as communal grazing lands and that farmers are very interested in improvement measures to raise their productivity. Since to date there has been no research dealing with such native, communal pastures, C2.2 proposes to assess, in particularly close cooperation with A1.2 and F1.2, their role, productivity, forage value, and land use patterns leading to the development of grazing lands, by means of (1) PRA surveys and (2) primary-production and nutritive-value studies based on appropriate vegetation samplings (exclosures) on-farm during the rainy and dry seasons. ...Also this work will have close links with A1.2 and F1.2, in addition to D2.2. The expected outcome of the proposed research will be the availability of knowledge about and understanding of (1) the variability in the Flemingia macrophylla core collection regarding its forage and soil reclamation potential; (2) the influence of land use on the development of communal grazing lands and their contribution to local livestock production systems; and (3) promising pasture grass and legume species adapted to prevailing edaphic, climatic and management conditions....
Funding period: 2003 - 2006
Relevancy: 48%
Identification, modification and deployment of genetic factors controlling resistance to important pathogens in barley (Project)
...For RphMBR1012 a high resolution map from 4775 F2 plants was constructed using a set of 55 markers. The target interval was delimited to 0.45 Mb containing 29 genes. For rym15 two maps were constructed using 527 F2 plants were constructed and the gene harbouring interval delimited to 140Mb. In a next step, 5,000 F2 plants will be screened and develop a high density and resolution map of rym15 will be constructed....
Funding period: 2017 - 2019
Relevancy: 48%
Reformulation – fat reduction in deep-fat fried bakery products (Project)
...The project includes three different strategies, which are applicable at low cost and / or adaptable from other types of food: 1) physical modification of flour, 2) application of additives and 3) coating with hydrocolloids. ...In the first step a method to observe the fat migration will be established and the standard recipe will be characterized (AP 1). Afterwards, the water binding of the flour will be increased by physical modifications, so that the oil uptake will be reduced (AP 2-4). ...A different approach is to apply a hydrocolloid coating to reduce the water evaporation and hence oil absorption post-frying (AP 7-9). From each of these approaches the most promising recipes with regard to fat content and sensory properties will be selected and compared by an untrained sensory panel (AP 10). ...
Funding period: 2016 - 2018
Relevancy: 48%
Increasing protein use efficiency in bread wheat with innovative breeding research on the MAGIC-WHEAT population WM-800 for effective climate change mitigation in the cereal value chain (Project)
...WP 2 comprises field trials, where lines of the MAGIC-Wheat population WM-800 contrasting in baking quality and the HIF lines from WP 1 are grown. ...In WP 7, the QTL effects for protein use efficiency and baking quality are validated from the field data of the HIF lines (WP 2) and the corresponding analyses from WPs 3 to 6. ...In WP 8, a model-based evaluation of the GHG mitigation potential of new wheat genotypes will be carried out based on the field data of the cultivation trials (WP 2) and the corresponding analyses in WP 3 to WP 7....
Funding period: 2024 - 2027
