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Relevancy: 9%
Investigation of food products illegally introduced into Germany by airport luggage for the presence of the non-endemic pathogens Brucella and ('2010:Trichinella'). (Project)
Commission regulation (EC) No 745/2004 requires that Member States ensure that no products destined for human consumption are introduced into the Community from a third country without having been subjected to the appropriate veterinary checks. Regardless, approx. 17500kg illegal food products are confiscated yearly at the Frankfurt International Airport. The import of such potentially...
Funding period: 2009 - 2010
Relevancy: 9%
Phylogenetic analyses of Avian Influenzaviruses from wild birds in Ukraine and their connection to Isolates in Europe in the period 2010-2020. - Scientific Exchange (Project)
The avian influenza virus (AIV) poses a major threat to human and animal health, in particular to domestic poultry and wild birds. The biological characteristics of the virus lead to several unique features. Thus, the virus has the potential for reassortments, the exchange and recombination of whole genes. The resulting new variants, while occurring regularly, are not predictable. The high...
Funding period: 2020 - 2022
Relevancy: 6%
Development of a contact allergen-induced T-cell assay using Langerhans cells: 2009: Expression of lineage specific T-cell transcription factors as biological endpoint suitable to indicate chemical induction of sensitization 2010: Measurement and quantification of transcription factors via qRT-PCR and FACS (Project)
Culture systems of dendritic cells are currently in the focus regarding development of in vitro test methods for sensitizing compounds present in consumer products. Allergen-reactive cytotoxic T-cells are responsible for typical tissue damages arising in the process of contact dermatitis. In order to imitate such type IV allergic reactions in skin of experimental animals, in this project...
Funding period: 2009 - 2010
Relevancy: 6%
Fishery-biological investigations on whitefish stocks in pre-alpine lakes (Project)
no details
Funding period: 1975 - 2037
Relevancy: 6%
Real-time immuno-PCR for the detection of animal bone and tissue marker 2010: Validation of an immunological method for the detection of Osteocalcin representing a stable bone tissue marker in Meat and Bone Meal (MBM) (Project)
Feeding of animal protein to farmed animals is - with just a few exceptions - not allowed according to Regulation (EC) No. 999/2001. The official method for the detection of animal particles in feed is based on microscopy Regulation (EC) No. 152/2009). However, microscopy cannot distinguish animal species. Further quantitative analysis poses a problem as demonstrated in ring trials organised by...
Funding period: 2008 - 2010
Relevancy: 6%
Identification of Nrf2-target genes in human THP-1 monocytes 2009: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis 2010: Identification of Nrf2 target genes in human THP-1 monocytes upon treatment with contact allergens by means of proteomic analysis (Project)
This study is to identify detoxifying enzymes or proteasomal components in THP-1 mono-cytes that are regulated by the transcription factor Nrf2. The induction of expression of such proteins may indicate a cellular stress response, e.g. upon exposure to sensitizing agents. Cells that are stably expressing RNAi against Nrf2-RNA down-regulating Nrf2 (RNAi-gene knock down) may not react adequately by...
Funding period: 2008 - 2010