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Search for: fh62VKoX2FU0lEOwkF43GA7tzz7cUk55eQG9OuEGpGyuFcwfwqofu1SOH9bhwXJO, 10 of 7923 ResultsSorting
Relevancy: 54%
Collaborative project: User support in evaluating the trustworthiness of websites and webshops (Internet Usage Support: InUse) – Subproject 4 (Project)
...This objective is dived in three sub objectives: 1. Development of a tool to judge on the trustworthiness of a webpage and in particular of web shops and to provide feedback to the user in terms of warnings and hints to proceed. 2. ...The project is structured in the following working pages WP1 State of the Art; WP2 Concept for Security Analysis; WP3 Risk Profile; WP4 Concept for Context Analysis; WP5 Evaluation Concept; WP6 Warnings, Hints, and Recommendations how to proceed; WP7 Handling False Positives and False Negatives; WP8 Anonymisation Concept; WP9 Security Analysis of the Updating Concept and Scientific Monitoring; WP10 Security Analysis Authenticity Protection of the IT Security Seal and Scientific Monitoring; WP11 Realization; WP12 User test; WP13 Project Management....
Funding period: 2012 - 2015
Relevancy: 54%
Selection and improving of fit-for-purpose sampling procedures for specific foods and risks (BASELINE) (Project)
...The selected protocols and methods should be able to produce suitable data for risk analysis * To develop predictive mathematical models for biological risks and investigate and model sources and pathways of chemical contaminants to improve sampling schemes * To validate and harmonise the sampling schemes developed in the project and alternative detection methods * To share and disseminate the scientific knowledge deriving from the project to stakeholders The BASELINE work plan has been divided in 9 work packages: * WP1- management * WP2-WP6 sampling protocols for specific food matrixes * WP7-risk modelling * WP8-validation and harmonisation of sampling protocols * WP9-dissemination and training The major output of the project is to generate new knowledge on sampling schemes for risk assessment by using a mathematical approach for different groups of food products as seafood, eggs and egg products, fresh meats, milk and dairy products and plant products. ...
Funding period: 2009 - 2013
Relevancy: 53%
Development of a molecular diagnostic for sustainable and resource-efficient production of the renewable resource potato starch. Subproject 4 (Project)
...The following results have been achieved in the reporting period: WP1 Development of molecular markers for resistance to pathotypes 1,2,6,18: Extensive resistance tests were performed for the following groups of material: a) Potato varieties with known resistance spectrum: The inoculum for the tests of 47 varieties with multiple resistance, 50 varieties with P1 resistance, 50 varieties with P1 susceptibility and 80 wild species with unknown resistance or susceptibility to potato wart disease was increased for all four pathotypes (in total 15,900 warts). b) Segregating populations: 24 genotypes were infected with pathotype 1 and 18 genotypes with P18, seedling tissue was taken after 2, 7, 14 and 21 days and frozen, then shipped to partner LUH. c) Crossing populations with other donors of resistance: The parents of each crossing populations were tested with all four pathotypes (588 tubers). 150 genotypes of the population Panda x L04 were tested with 20 tubers on pathotype 18 and the distribution of the means was calculated. WP 3+4: Identification of candidate genes by proteom analysis of the infection course and mechanism of infestation course: JKI (AG Flath) has provided the partner LUH with P18 infected tuber material at regular intervals. WP1 Development of molecular markers for resistance to wart pathotypes: Extensive resistance tests were performed for the dihaploid population of Karolin x Solanum phureja as well as with an extensive varietal panel. ...WP 3+4: Identification of candidate genes by proteom analysis of the infection course and mechanism of infestation course: JKI has provided the LUH with P18 and P1 infected tuber material at regular intervals. ...
Funding period: 2013 - 2017
Relevancy: 53%
Modern molecular diagnostic methods: Development and use of the DNA chip technology for comprehensive influenza virus diagnostics (Project)
...We plan to establish systems which in addition to subtyping of H5 and H7 permit the rapid identification of all currently existing HA subtypes (H1 to H16) and NA subtypes (N1 to N9). ...Currently occurring H5N1 isolates can thus be classified into specific genotypes, and genetic elements which are a sign for an adaptation of a current avian influenza A virus to other hosts (e.g. humans) can rapidly be detected. ...Thus, point mutations in the nonstructural proteins as well as special sequences in gene segments with important pathogenetic properties (e.g. NS1) can be differentiated d)Parallel differential diagnostic identification of other pathogens which are of importance in veterinary medicine, such as e.g. an infection with Newcastle Disease virus (“atypical fowl plague”). ...
Funding period: 2006 - 2009
Relevancy: 53%
Collaborative project: Sensor-based online detection of diseases in cereals - subproject 1 (Project)
...Using spectral features with the optical close-range sensors and also with the aerial UAV-images differences between infected and control plots (9 m x 9 m) were detected early enough to control the disease in practice. The close-range color images were sufficiently proximal (2 m above ground) to classify the uredospore layers which were arranged in a line using spectral and spatial features. ...
Funding period: 2016 - 2019
Relevancy: 53%
Collaborative project: Sensor-based online detection of diseases in cereals - subproject 2 (Project)
...Using spectral features with the optical close-range sensors and also with the aerial UAV-images differences between infected and control plots (9 m x 9 m) were detected early enough to control the disease in practice. The close-range color images were sufficiently proximal (2 m above ground) to classify the uredospore layers which were arranged in a line using spectral and spatial features. ...
Funding period: 2016 - 2019
Relevancy: 53%
Collaborative project: Sensor-based online detection of diseases in cereals - subproject 3 (Project)
...Using spectral features with the optical close-range sensors and also with the aerial UAV-images differences between infected and control plots (9 m x 9 m) were detected early enough to control the disease in practice. The close-range color images were sufficiently proximal (2 m above ground) to classify the uredospore layers which were arranged in a line using spectral and spatial features. ...
Funding period: 2016 - 2019
Relevancy: 53%
Molecularkinetic characterization of the transport and the distribution of the pro-carcinogene Benzo[a]pyrene in vitro and in vivo ? new kinetic data for risk assessment (Project)
...The interaction between the cytochrome P450-system, phase II xenobiotic-metabolizing en-zymes (XMEs) such as glutathione-S-transferases, UDP-glucuronosyl transferases and sul-fotransferases, and ABC-transport proteins is an important part of the mucosa of the small intestine acting as a potential biochemical barrier for nutritional- and eco-toxicological rele-vant compounds.Intestinal resorption of cancerogenic contaminants of food such as the polycyclic aromatic hydrocarbon (PAHs) benzo[a]pyrene (B[a]P) is affected by the interaction of CYP1A1/CYP1B1, phase II XMEs and ABC-transport proteins. It was shown that excretion of the B[a]P phase II metabolites including B[a]P-glucuronides and B[a]P-sulfates is medi-ated by breast cancer resistance protein (BCRP) (Ebert et al., 2005).In the project we here apply for the mechanism of detoxification of the ultimate carcino-genic phase I B[a]P metabolite anti-B[a]P-7,8-diol-9,10-epoxide (BPDE) will be studied. Formation of glutathione conjugates mediated by glutathione-S-transferases (GSTs) as well as the excretion of these conjugates will be analysed. ...Therefore, the double MRP2/3 knock out mouse will be employed to analyse the influence of MRP2 and MRP3 in the distribution of the metabolites of B[a]P....
Funding period: 2009 - 2009
Relevancy: 53%
Interaction between metabolism and transport of toxicological relevant compounds in the gastrointestinal barrier (Project)
...Intestinal resorption of cancerogenic contaminants of food such as the polycyclic aromatic hydrocarbon (PAHs) benzo[a]pyrene (B[a]P) is affected by the interaction of CYP1A1/CYP1B1, phase II XMEs and ABC-transport proteins. ...In the project we here apply for the mechanism of detoxification of the ultimate carcinogenic phase I B[a]P metabolite anti-B[a]P-7,8-diol-9,10-epoxide (BPDE) will be studied. Formation of glutathione conjugates mediated by glutathione-S-transferases (GSTs) as well as the excretion of these conjugates will be analysed. ...
Funding period: 2005 - 2009
Relevancy: 52%
Assurance and optimisation of food product and process quality by conventional and novel thermal processing methods (Project)
...Life Sci. 3 (4), 199-201; Mayer-Miebach E., Spieß W.E.L. (2003) Influence of cold storage and blanching on the carotenoid content of Kintoki carrots. Journal of Food Engineering 56 (2-3), 211-213.; Mayer-Miebach E., Gärtner, U., Großmann, B., Wolf, W., Spieß W.E.L. (2003) Influence of low temperature blanching on the content of valuable substances and sensory properties in ready-to-use salads. Journal of Food Engineering 56 (2-3), 215-217; Mayer-Miebach, E., Gärtner, U., Spieß, W.E.L. (2002): Minimal processing of ready-to-serve-leafy salads. ...
Funding period: 2001 - 2018
