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Improving the Bioavailability of Poorly Soluble Substances for the Identification of their Intrinsic, Single-Molecule Properties - Studies on the Micellar Formulation of Tattoo Pigments for Toxicological Assays (Project)

Tattoo pigments exhibit extremely low solubility in aqueous media and exist in micro and nanoparticulate forms due to molecule-specific properties. Owing to their strong tendency to aggregate, these substances are thus rather unable to interact with the biochemical cellular apparatus based on their single-molecule characteristics. However, these properties play a crucial role in metabolic...


Funding period: 2024 - 2025

Relevancy: 100%

Improving the effectiveness of non-chemical alternatives for the management of Norway rats (Project)

These rodents are usually managed by applying rodenticides. These substances can expose non-target species and the environment to risks. The use of snap traps could be a promising and environmentally friendly alternative to rodenticides in certain areas. The (partial) replacement of anticoagulant rodenticides by traps would reduce the release of PBT substances into the environment. Optimal snap...


Funding period: 2024 - 2027

Relevancy: 100%

Characterisation of the first engineered nanomaterial approved as a Novel Food in the EU: Iron Hydroxide Adipate Tartrate (IHAT) (Project)

Iron hydroxide adipate tartrate (IHAT) is the first engineered nanomaterial authorised by the EU as novel food and added to the Union List of Authorised Novel Foods for its use as a source of iron in food supplements (COMMISSION IMPLEMENTING REGULATION (EU) 2022/1373, COMMISSION IMPLEMENTING REGULATION (EU) 2017/2470). In the Implementing Regulation (EU) 2022/1373, which allows the placing on the...


Funding period: 2023 - 2024

Relevancy: 100%

Development and application of novel methods for characterization of foodborne viruses (Project)

In the project, novel methods will be developed and applied, which could enable a better characterization of foodborne viruses. Viruses that can be transmitted by food show an increasing importance for diseases of humans and for foodborne outbreaks. This includes noroviruses and rotaviruses, which can cause gastroenteris, as well as hepatitis A and E viruses, which lead to liver inflammation. For...


Funding period: 2024 - 2028

Relevancy: 100%

Further development of methods for recording, modelling and assessing emissions in livestock housing (Project)

Further development of methods for recording, modelling and assessing emissions in livestock housing


Funding period: 2023 - 2028

Relevancy: 100%

TiKoPLUS – animal welfare, competence and cooperation between learning locations (Project)

The project strengthens cooperation between learning locations in the agricultural sector and ensures the pedagogical professionalization of educational staff through animal welfare-oriented educational modules and teaching-learning settings. The agricultural sector is facing major challenges, not only due to structural changes, but also because of increased societal demand for higher animal...


Funding period: 2025 - 2027

Relevancy: 100%

Identification of future breeding potential for more climate protection in plant production - assessment of the contribution of breeding progress to reducing the CO2 footprint (Project)

Based on extensive variety trial data, the contribution of breeding progress to climate protection for the most relevant crops in Germany is evaluated using life cycle analysis (LCA) and statistical methods. Relevant plant characteristics for climate protection are identified and future breeding potential for more climate protection in plant production is shown. The project builds on the...


Funding period: 2022 - 2025

Relevancy: 100%

An in silico/in vitro hybrid method using inducible Estrogen/Androgen receptors (ER-α/AR-β) to screen EDCs from tattoo inks/PMU (Project)

Obj. 1 QSAR toolbox pre-screening of potential pleiotropic classification of tattoo colorants into EDCs category. As a first step, we will categorize tattoo pigments/PMU into EDCs catgory based on their binding ability with different hormone receptor. Obj. 2 In chemico experimental binding using Microscale Thermophoresis (MST) to measure binding affinities of colorants flagged in QSAR as EDCs. As...


Funding period: 2023 - 2024

Relevancy: 100%

Studies on the functional effect of mixtures on processes of potentially dominant molecular and cellular antigen recognition and immunotoxicity (Project)

Objectives: Consumer products consist of chemicals of different origin and composition. In the present project, existing and new (immune) assays will be used to compare immunotoxicological single substance effects of an isothiazolinone preservative (such as BIT or OIT; all potential allergens) with known MIXTURES of isothiazolinones (e.g. MI plus BIT or OIT) with regard to their molecular...


Funding period: 2024 - 2024

Relevancy: 100%

Validation of the usability of zooplankton as a temporal integrator of pesticide contamination in small water bodies (Project)

In the project, 30 small standing waters in Germany (Brandenburg) and 30 small standing waters in Spain (Catalonia) are being investigated with regard to the concentrations of pesticides in surface water and zooplankton. We assume that the analysis of pesticides in zooplankton will provide information on long-term pesticide exposure, as the organism can accumulate the active substances over time....


Funding period: 2024 - 2026