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Search for: erz0sxl5g8vvmvn4ys3t2pck0tnkfwpqiy0xemsfsppa1u1ofavfhpib7g9htmdy, 10 of 7966 ResultsSorting
Relevancy: 34%
Collaborative project: Comprehensive communication and cloud networks for agriculture 4.0 and rural areas. Subproject 3 (Project)
...The aim of the project is the development of a digital experimental environment with a focus on necessary communication and cloud infrastructures for the research and testing of technologies for area-wide wireless data transmission with the help of 5G in rural areas and networking of agricultural enterprises in a selected model region of Saxony. In the test bed, specific use cases are developed on which the manufacturers of communication hardware build their 5G products. The test field is a platform and showcase with non-discriminatory access for testing and demonstrating new and future digitalisation applications for agricultural purposes and for innovation in rural areas. ...WP 2: 5G-based experimental field Planning, conception, architecture, implementation and operation. ...
Funding period: 2019 - 2024
Relevancy: 34%
Molecular characterization of toxicological properties of the marine biotoxin okadaic acid in in vitro models for the human intestinal barrier and liver (Project)
...After 8- and 24-hour treatment of the Caco-2 cells with okadaic acid (80 and 150 nM, respectively), the genes CLDN2, CLDN4 and TJP1 were upregulated. ...The investigation of the metabolism of okadaic acid showed a toxification of okadaic acid by an increased induction of cytotoxicity to the liver cell line HepG2. Enzymes contributing to metabolism are CYP3A4 and CYP3A5 and the corresponding rat orthologues. For human CYP1A2, okadaic acid has been shown to be toxic by increased cytotoxicity in HepG2 cells. ...
Funding period: 2015 - 2019
Relevancy: 34%
BMEL - Research Cooperation for Global Foodsecurity (Funding programme)
...This funding instrument has the following main objectives: 1) The development of approaches for improved and sustainable food security. 2) The exploration of solutions along the value chain. 3) The involvement of relevant partners according to the research topic and the needs in the target country or target region. Here, the research consortium should also provide interfaces to partners in the field of development, to governmental organisations and NGOs. 4) Approaches and findings from research projects have to be integrated into regional development processes, e.g. through cooperation with regional networks and research fora. 5) Besides research, also tasks in the area of capacity development and information and knowledge management will be supported. 6) Ths instrument aims at contributing towards the realisation of activities in terms of the MDG’s and the post -2015 development agenda....
Relevancy: 34%
Geospatial ICT infrastructure for agricultural machines and Farm Management Information Systems (FMIS) in planning and operation of precision farming (Project)
...Recent developments (e.g ISO 191xx, agroXML, ISOBUS, INSPIRE, GDI-DE, Web 2.0 and OGC) will be taken into account. ...
Funding period: 2011 - 2013
Relevancy: 33%
Risk assessment tools for the safety of global food and feed supply chains (Project)
...BfR parts of the project: Area 1: Map and analyse global food and feed supply chains Area 2: Establishment of a European food and feed safety model repository Area 3: Implementing uncertainty analysis in food and feed safety assessment Area 4: Strengthen regional networks for crisis preparedness and communication in times of crisis. ...For this a specific work package (Area 0) on reporting and communication will be defined....
Funding period: 2017 - 2019
Relevancy: 33%
Zoonoses Anticipation and Preparedness Initiative (Project)
...To develop these pipelines, the project will focus on three priority pathogens: 1) Rift Valley fever virus (RVFV) 2) Schmallenberg virus (SBV) 3) Middle East Respiratory Syndrome Coronavirus (MERS-CoV). ...Rissmann et. al. 2017 Jan 23;35(4):655-662. doi: 10.1016/j.vaccine.2016.12.003 The amino terminal subdomain of glycoprotein Gc of Schmallenberg virus: disulfide bonding and structural determinants of neutralization Roman-Sosa et. al. 2017 Jun;98(6):1259-1273. doi: 10.1099/jgv.0.000810. ...
Funding period: 2015 - 2020
Relevancy: 33%
Mode of Action of 3-chloro-1,2-propanediol (3-MCPD) and of 2-chloro-1,3-propanediol (2-MCPD) (Project)
...Fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD) and of 2-chloro-1,3-propanediol (2-MCPD) are formed during heat treatment of numerous foods, e.g., during the refinement of vegetable fats and oils. After ingestion, the esters are hydrolyzed in the gut, thereby releasing free 3-MCPD and free 2-MCPD which are then resorbed into the body. 3-MCPD is a non-genotoxic carcinogen and was classified by the International Agency for Research on Cancer (IARC) as being possibly carcinogenic to humans (class 2B). ...Urgent needs for research has been identified for the ongoing risk assessment of 3-MCPD and of 2-MCPD in order to clarify open toxicological questions. ...
Funding period: 2016 - 2017
Relevancy: 33%
Optimizing the pain management in the mouse-osteotomy-model – Integration of a refinement study in a basic research study (Project)
...Different dosages of Tramadol according to the GV-SOLAS recommendations will be compared (0,1 mg/ml und 1 mg/ml) as well as Buprenorphine (0,009 mg/ml) as potent alternative. ...The application of analgesics in adequate dosages of Tramadol and Buprenorphine via the drinking water is suitable for pain management in the mouse-osteotomy-model. Within the 3 days post-OP, the animals take up continuously the treated drinking water. ...
Funding period: 2016 - 2016
Relevancy: 33%
Unraveling the genetic architecture of winter hardiness and quality traits in durum by genome wide and canidate gene based association mapping (Project)
...Thereby a major QTL, which was found in T. monococcum, T.aestivum, H. vulgare and S.cereale on chromosome 5, seems especially important. ...Thereby, the objectives are to (1) determine the genetic variance, heritability and correlations among frost tolerance and quality traits, (2) examine linkage disequilibrium and population structure, (3) investigate sequence polymorphism at candidate genes for frost tolerance, and (4) perform candidate gene based and genome wide association mapping....
Funding period: 2012 - 2015
Relevancy: 33%
Long-term field trial on scenarios of plant protection (Project)
...Compared with the earlier demands for a reduction in the quantity of crop protection products, some people reject chemical synthetic crop protection completely, or demand that entire groups of plant protection products be banned (e.g. azoles). Against this background, the Chemical Pesticide Reduction Programme (BS4) was redesigned to compare plant protection scenarios.In comparison to the strategy "Comparison of environmentally friendly plant protection (BS1)", this trial examines "hard" cuts in plant protection in close spatial proximity.The following scenarios could be realised in the fielld trial:Scenario 1:Without chemical synthetic plant protection (the previous variant 1 is retained due to the character of long-term field trials), i.e. it can be based on results since 2002. ...Here too, it is possible to build on the results since the experiment was established (cf. previous variant 2). As a side-effect, this strategy allows a long-term yield statement to be made at the Dahnsdorf site.Scenario 3:Renouncement of active substances from the list of CFS candidates (candidates for substitution), see: http://ec.europa.eu/food/plant/pesticides/approval_active_substances/docs/draft_list_cfs_en.pdf This scenario assumes that this list is implemented 1:1 and that the concrete choice of means would thus be considerably restricted. ...In order to ensure a differentiation from scenarion 1 and 2, clear decision criteria are established (e.g. minimum efficiency of the alternative, always preferable alternative, etc.). ...
Funding period: 2020 - 2022
