We use cookies to enable you to make the best possible use of our website. Only cookies that are necessary for the operation of the site are set. Details in our privacy policy.
Data Protection Declaration
Imprint
Advanced Search
Search results
Search for: erz0sxl5g8vvmvn4ys3t2pck0tnkfwpqiy0xemsfsppa1u1ofavfhpib7g9htmdy, 10 of 8065 ResultsSorting
Relevancy: 40%
Development of a 'Contact Allergen Activated T-Cell (CAATC)-Assay' using dendritic cells from skin: characterization of the sensitizing potency of chemicals via dendritic cell-induced expression of lineage specific T cell transcription factors (Project)
...In cocultures of LCs together with CD4+ T cells, polarization of naive T cells toward specific effector T cells will be induced after subsequent interaction. The following biological endpoints will be explored in the CAATC-Assay: 1. Chemotactic migration of LCs through a 8 µm porus of a Transwell-system; 2. Flow cytometric characterization of cell surface markers like costimulatory and adhesion molecules on LCs; 3. Expression of transcription factors specific for effector T cell subpopulations by quantitative real-time-PCR.In our in vitro allergy testing system the transcription factors Runx3, T-bet, GATA-3, RORC2, and FOXP3 will be evaluated for the first time according to their eligibility to serve as functional markers for induction of CTLs, TH1, TH2, TH17, or regulatory T cells (TReg). qRT-PCR analyses of the expression of effector T cells are expected to point to specific surface markers...
Funding period: 2010 - 2012
Relevancy: 40%
Collaborative project: Selective, non-chemical control of toxic plants in extensive grassland. Subproject 1 (Project)
...For this purpose, a driverless, 0.40 m wide mower and, alternatively, a tractor-coupled water jet device with a working width of 2.50 m, divided into 10 individually switchable sections, were set up. ...In spring, the devices removed the plants from the grassland according to this map. A repeated measure 2 to 3 weeks later reduced the stock to 0 to 2 plants per m² at the time of the hay harvest in mid-June."...
Funding period: 2018 - 2021
Relevancy: 40%
Collaborative project: Selective, non-chemical control of toxic plants in extensive grassland. Subproject 2 (Project)
...For this purpose, a driverless, 0.40 m wide mower and, alternatively, a tractor-coupled water jet device with a working width of 2.50 m, divided into 10 individually switchable sections, were set up. ...In spring, the devices removed the plants from the grassland according to this map. A repeated measure 2 to 3 weeks later reduced the stock to 0 to 2 plants per m² at the time of the hay harvest in mid-June."...
Funding period: 2018 - 2021
Relevancy: 40%
Regeneration, Maintenance, and Sustainable Use of Pristine Forests in Ethiopia (Project)
...This requires the employment of a project-coordinating scientist. His tasks will be (1) to coordinate the field work, (2) to administer the field station and the project car, (3) to manage the permanent plots, (4) to establish and coordinate the experiments of the silviculture project, (5) to organise training activities for Ethiopian students and professionals, (6) to deal with Ethiopian authorities, (7) to interact with the Addis Ababa University and the Ethiopian Agricultural Research Organization, (8) to strengthen networking within the project package, and (8) to take the lead in the preparation of a manual for the sustainable management of the Munessa-Shashemene Forest....
Funding period: 2005 - 2010
Relevancy: 40%
Determination of chlorinated paraffins in nut nougat- or chocolate cream based on palm oil (Project)
...Furthermore, this food group has a high market relevance for the sensitive consumer group of infants.CPs were detected in 15 of the 30 samples tested (50 %). SCCPs (24-87 ng/g FW) and MCCPs (50-350 ng/g FW) were identified in 12 samples each (40 %), in nine (30 %) of which SCCPs and MCCPs were present side by side (and thus three samples each contained only SCCPs and MCCPs respectively). The median CP-containing sample was significantly higher for MCCPs (96 ng/g FW) than for SCCPs (35 ng/g FW). The ∑CP contents of the positive samples ranged from 24 to 350 ng/g FW, with a median value of all 30 samples of 18 ng/g FW (including negative results with 1/2 NG; median of CP-containing samples 140 ng/g FW). ...Besides palm oil, the most frequently labelled fats were sunflower oil (17 sampled), rapeseed oil (9 sampled) and cocoa butter (5 sampled). In addition, 28 samples contained hazelnuts. ...
Funding period: 2019 - 2020
Relevancy: 39%
Collaborative project: Investigation of possbilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial slaughterhouses - subproject 1 (Project)
...The aim of the project is to investigate possibilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial plants. 1.development of stimulus methods, 2. identification of adequate stimulus and development of possibilities of the technical implementation and stimulus release, 3. investigation of stimulus methods with different stunning procedures, 4./5./6. development of camera system, software and control, 7. further specification of the procedure under conditions of praxis in the industrial plants....
Funding period: 2012 - 2014
Relevancy: 39%
Collaborative project: Investigation of possbilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial slaughterhouses - subproject 2 (Project)
...The aim of the project is to investigate possibilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial plants. 1.development of stimulus methods, 2. identification of adequate stimulus and development of possibilities of the technical implementation and stimulus release, 3. investigation of stimulus methods with different stunning procedures, 4./5./6. development of camera system, software and control, 7. further specification of the procedure under conditions of praxis in the industrial plants....
Funding period: 2012 - 2014
Relevancy: 39%
Collaborative project: Investigation of possbilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial slaughterhouses - subproject 2 (Project)
...The aim of the project is to investigate possibilities on the application of an automated procedure for the detection of the secure onset of death of slaughter pigs in industrial plants. 1.development of stimulus methods, 2. identification of adequate stimulus and development of possibilities of the technical implementation and stimulus release, 3. investigation of stimulus methods with different stunning procedures, 4./5./6. development of camera system, software and control, 7. further specification of the procedure under conditions of praxis in the industrial plants....
Funding period: 2012 - 2014
Relevancy: 39%
Mechanical analysis of liver-toxic substances in a hepatic co-culture model (Project)
...In this study we established and utilized a co-culture model composed of hepatocytes (HepG2) and monocyte-like cells (THP-1) in order to minimize animal experiments. ...In this project we quantified more than 1,000 Proteins in THP-1 as well as in HepG2 cells after treatment with 3 different concentrations of ketoconazole (typical hepatotoxic substance) and o-anisidine (example of migrating substance) in single as well as in the co-culture model. Additionally, ketoconazole and ketoconazole metabolites were quantified in HepG2 und THP-1 cells as well as the supernatants to draw conclusions on the exposition scenarios. ...
Funding period: 2014 - 2015
Relevancy: 39%
Identification of satiating compounds in dietary fats and optimization of low-fat foods by adding satiating lipoid compounds (Project)
...The aim of this project was to evaluate the satiating effects of different types of fat in two human intervention studies, and to elucidate the molecular mechanisms in cell culture experiments using human hepatic cancer cells (HepG2). In the first human intervention study, total amounts of 8 % olive oil, canola oil, lard or milk fats were added to low-fat yoghurt (0.1 % fat). ...In a second human intervention study, 500 g low-fat yoghurt (0.1 % fat) was enriched with an aroma extract prepared from 120 ml olive oil. ...In these experiments, hexanal and E2-hexenal being two of the predominant aroma active compounds in olive oil, were identified as key active compounds. ...
Funding period: 2009 - 2012
