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Studies on the anti-oxidative responses of lung cells as an endpoint for the assessment of aerosols after exposure at the air-liquid interface (Project)

For the toxicological investigation of substances, which can enter the human body by inhalation, there are so far no accepted alternatives for animal tests. This applies in particular to insoluble nanoparticles. Therefore, new methods must be developed for the evaluation of the toxic potential of nanoparticles in occupational atmospheres, e.g. during the production by nanoparticles, or during the...


Funding period: 2007 - 2011

Relevancy: 100%

Development of Predictive In Vitro Test for Developmental Neurotoxicity testing (Project)

Given the significant potential of chemicals and drugs to interfere with development of the nervous system, regulatory test guidelines have been adopted for the prediction and assessment of developmental neurotoxicity (U.S.EPA OPPTS 870.6300 and OECD TG 426). However, current in vivo test methods are laborious, costly and necessitate use of high numbers of laboratory animals. Around 1000 pups...


Funding period: 2007 - 2011

Relevancy: 100%

Best Search Practice on Animal Alternatives - A Guide for Untrained Database Users (Project)

The aim of the project is a comprehensive guide, at various levels, reviewing all relevant data retrieval systems in the area of toxicology and biomedical sciences with relevance to animal alternatives and providing guidance on a step-by-step approach for data retrieval procedures for untrained database users and National Authorities responsible for granting project licenses for the performance...


Funding period: 2006 - 2011

Relevancy: 100%

Mechanical weed control in organic strawberry production (Project)

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Funding period: 2012 - 2014

Relevancy: 100%

New earliness methods for cut perennials from open ground (Project)

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Funding period: 2012 - 2014

Relevancy: 100%

Energy utilization from herb-rich sowing in the agricultural landscape - an ecological and economical alternative for the production of biogas (Project)

Herb-rich sowings promise to reduce conflicts between energy crop production and protection of the environment and to ease the growing area competition. The attractive crops increase the diversity in the landscape and reduce the risk of erosion by covering the soil surface throughout the year. The project aims to develop an economically sound cropping system based on perennial, herb-rich plant...


Funding period: 2012 - 2015