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Relevancy: 100%
GlobE - Future-oriented research for food security in East Africa (Project)
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Funding period: 2012 - 2012
Relevancy: 100%
GlobE - vinasse as a raw material for production of high quality feed and food products based on brine shrimp and algae - an integrated approach to sustainable biofuels and food production as a contribution to food security in Africa (Project)
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Funding period: 2012 - 2012
Relevancy: 100%
Characterization of cellular effects of contact sensitizers in vitro: Analysis of phosphotyrosine signaling pathways by far western blotting and establishment of a screening method (Project)
A range of low molecular weight chemicals can induce allergic contact dermatitis. In the development of allergic contact dermatitis two phases can be separated: sensitization and elicitation. During sensitization contact allergens or sensitizers penetrate through the skin barrier and interact with epidermal dendritic cells (Langerhans cells), which then may become activated and will migrate...
Funding period: 2010 - 2010
Relevancy: 100%
Transfer and transformation of DSP toxins in blue mussels (Mytilus edulis L.) (Project)
Diarrhetic shellfish poisoning (DSP) is the most occurring intoxication in Europe after con-sumption of mussels. DSP is caused by marine biotoxins of okadaic acid group. Toxins are produced by Dinoflagellates of Dinophysis and Prorocentrum type. A lot of scientific work was done concerning uptake and transformation of these toxins in mussels but up to now processes are not fully known.Factors...
Funding period: 2010 - 2010
Relevancy: 100%
Development and validation of methods for the simultaneous determination of more than 500 pesticides in food and water using Q TRAP LC-MS/MS (Project)
The spectral library of 541 pesticides prepared by the BfR in combination with the LC-MS-QTrap technology allows the simultaneous determination and confirmation of more than 500 pesticides in one run. Compared to this new technique the conventional LC-MS/MS is lim-ited to the analysis of approximately 250 pesticides in parallel. By the validation of the measuring method consisting of detection,...
Funding period: 2010 - 2010
Relevancy: 100%
Investigations on the carry over of Maduramicin from feed to egg (Project)
Maduramicin is licensed in the European Union as feed additive for turkey and chickens for fattening. During manufacturing of feedstuffs a certain amount of previously produced batches remains in theproduction line and causes a contamination of the subsequent produced feed. This crosscontamination resulted in a possible residue of maduramicin in feed material intended for use in nontargetanimals....
Funding period: 2010 - 2010
Relevancy: 100%
Feeding of contaminated feed with tansy ragwort (Senecio jacobae) to small ruminants to determine the carry over rate of pyrrolizidine alkaloids in milk from small ruminants and to evaluate and validate a test method for the detection of PA´s in naturally contaminated samples (Project)
The changing in the agriculture from intensive to extensive using of fields cause in an in-crease of unpleasant plants, especially plants, who include Pyrrolizidine alkaloids.Normally the plants are avoided from animals but they can not sort them out in hey or silage and the Pyrrolizidine alkaloids do not loose their poisoning potential. Carry over from Pyrrolizidine alkaloids is a problem in the...
Funding period: 2010 - 2010
Relevancy: 100%
Investigations of the microbial status of caviar from the retail market and wholesale with special emphasis of the occurrence of aquatic mycobacteria. (Project)
Infections of fish with aquatic mycobacteria, especially with Mycobacterium (M.) marinum, M. chelonae und M. fortuitum result in chronically and, rarely acute disease. Almost all ma-rine and freshwater fish (wild catch, aquaculture) are susceptible to these bacteria. Aquatic mycobacteria represent a zoonosis which could lead to infections in man whereby immun-compromised persons or humans with...
Funding period: 2010 - 2010
Relevancy: 100%
Analysis of the effects of developmental toxins from consumer products on microRNA (miRNA) expression during differentiation of embryonic stem cells. Identification of novel molecular endpoints and studies on the role of miRNAs in developmental toxicity (Project)
Studying chemical disturbances during differentiation of murine embryonic stem cells (ESC) has been established at ZEBET as an alternative in vitro testing approach for identification and classification of embryotoxic compounds. In particular, the expression of specific marker genes demarcating the formation of neural cell types is used as a molecular endpoint to measure embryotoxicity. miRNAs...
Funding period: 2010 - 2010
Relevancy: 100%
Evaluation of the genotoxic potenital of selected synthetically synthesized nanomaterials through application of alternative methods (Project)
For regulatory purposes current genotoxicity tests are not sufficiently developed. Methods to be used should be accommodated to the testing of nanomaterials and subsequently being harmonized. With selected nanomaterials originating from the Joint Research Council materials repository, well characterized materials shall be investigated with respect to their genotoxic hazard potential. Three assays...
Funding period: 2010 - 2010
