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Relevancy: 100%
Integrated weed management (IWM) in arable farming (Project)
Weed control in conventional farming has so far been carried out almost exclusively by the use of herbicides. Through primarily economically oriented crop rotations and production methods, high weed densities and difficult-to-control weeds, right up to the development of herbicide-resistant populations, are tolerated and, if necessary, regulated by the use of glyphosate. The research project...
Funding period: 2019 - 2025
Relevancy: 100%
Sex determination in pigs by CRISPR/Cas (Project)
The aim of the project is to determine the possibility to influence the sex of pig offspring by CRISPR/Cas and to determine the function of the SRY gene in pigs. In a first step, we characterize the function of the Y-chromosomal porcine SRY gene in the process of sex determination. Therefore, a SRY-specific CRISPR/Cas expression vector will be transfected into male porcine fibroblasts and the...
Funding period: 2017 - 2020
Relevancy: 100%
Experimental TBEV infection of bank voles (Myodes glareolus) (TBENAGER II) (Project)
The interaction between bank voles (Myodes glareolus) and ticks in relation to the transmission of tick-borne encephalitis virus (TBEV) will be investigated in more detail. For this purpose, the natural transmission cycle will be simulated under laboratory conditions. The established model will enable the testing of TBEV isolates under nature-like conditions and therefore reveal possible...
Funding period: 2020 - 2022
Relevancy: 100%
Investigations of the interactions of zoonotic pathogens in humans and animals (Project)
As part of the population-based project Study of Health in Pomerania (SHIP) a third cohort (NEXT) is established in 2021. Within the NEXT module “One Health”, animal contacts (dog, cat, poultry) of the 0 randomly selected participants (20-79 years) will be investigated and risk factors for zoonotic transmission as well as husbandry and environmental conditions examined. The aim is to gain a...
Funding period: 2020 - 2025
Relevancy: 100%
Analysis and molecular biological investigations on the impact of mutagenic biosynthesis percursors of the mycotoxin aflatoxin B1 in food (Project)
- Development of analytical methods for the quantification of mutagenic aflatoxin B1 precursors - Creation of a database on the occurrence of the mentioned toxin in food and feed - Elucidation of the in vitro metabolism and evaluation of combinatory toxicity of the toxins
Funding period: 2020 - 2022
Relevancy: 100%
Development of analytical methods in terms of origin, processing and authenticity of different Moroccan edible oils and characterization of by-products of oil processing residues to ensure sales opportunities in the global market (Project)
The aim of the study is to investigate the influence of origin of the plants and storage and processing of the raw material on the composition of oil obtained from fruits of argan tree (Argania spinosa), cactus pear (Opuntia ficus-indica), desert date palm (Balanites aegyptiaca), real date palm (Phoenix dactyliferous) or Ziziphus lotus as potential oil sources for cooperatives. In addition, the...
Funding period: 2020 - 2023
Relevancy: 100%
Developement of an enzyme-linked assay (ELISA) for determination of pyrrolizidine alkaloid (PA)-protein adducts as biomarkers for the detection of PA-exposure in livestock (Project)
The project is part of the superordinate research project Pyrrolizidine Alkaloids (PA) Safe Feed. PAs are a group of phytotoxins widely present in herbal plants. Many PA-containing plants can cause severe acute and chronic liver injury in both, humans and animals. Based on new toxicological risk assessments, plants, seeds or parts of plants containing pyrrolizidine alkaloids (PA) have been...
Funding period: 2021 - 2023
Relevancy: 100%
Genome analyses of bacteriophages and their host cultures for the assessment of mechanisms of phageresistence. (Project)
Based on detailed information on molecular interactions between phage and host cells, systems for the establishing of phage-resistent starter cultures shall be developed. The genome of phage TP-J34 has been completely sequenced. A mutation was identified in the gene encoding the receptor binding protein, which interferes with the correct assembly of the phage. In a closely related phage (TP-EW)...
Funding period: 2001 - 2021
Relevancy: 100%
Bacteriophage monitoring in dairy plants (Project)
Collection of informations over the development of phage spectra in dairy plants, with the aim of developing strategies for avaoidance of phage infections ResultsBacteriophages from different dairy plants and different parts within the plants were detected, identified and characterized on a molecular level. The appearance of a new phage type could be documented. Strategies for avoidance were...
Funding period: 2001 - 2021
Relevancy: 100%
Development of lactic acid bacteria for use in fruit and vegetable fermentations (Project)
Probiotic bacteria have so far been mostly applied in milk products. Recently, however, fruit juices containing probiotics have been developed. The development of new strains which will be investigated for their probiotic potential and their application in fermented vegetables or fruit products will be undertaken.
Funding period: 2001 - 2021