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Holistic utilization of mung beans and lentils - production of high-quality protein concentrates and utilization of side streams (Project)

The ‘Leg4Future’ project is aimed at the holistic utilisation of mung beans and lentils, as both raw materials have great potential but are currently still too little the focus of research. As part of Leg4Future, technofunctional protein concentrates are obtained that contain a minimal proportion of potentially antinutritional ingredients (ANF), which can impair the nutritional properties as well...


Funding period: 2024 - 2027

Relevancy: 100%

BfR-Center for Landuse related Assessments, One Health-Concepts (Project)

Goals of the BfR-center are - Initiation, planning, implementation of research projects in the field of land use-related evaluation methods and One Health concepts - Evaluation of the results of the research projects - Use of the results for publication and lectures as well as scientific advice from authorities - Cooperation with other federal institutions - Development and maintenance of...


Funding period: 2025 - 2025

Relevancy: 100%

Detection of antimicrobial resistance genes in complex samples (Project)

Antibiotic-resistant bacteria are spread globally and possible resistance mechanisms are diverse. Resistance spreads particularly easily where genes can be transferred between different bacteria through mobile genetic elements. It is difficult to get an overview about the resistance genes present in a complex sample (resistome) by using classic isolation methods and analysis of only a few...


Funding period: 2025 - 2025

Relevancy: 100%

One Health approach - examining environmental and animal samples for infectious agents (Project)

Acknowledging that the health of humans, animals and ecosystems is closely linked and can influence each other is a central element of the One Health concept (One Health High-Level Expert Panel et al., 2022). Climate change also plays an important role, as it increasingly affects humans, animals and ecosystems. Climate change also has a direct and indirect impact on infectious agents and thus on...


Funding period: 2025 - 2025

Relevancy: 100%

Development of a LAMP assay for the detection of C. difficile in food (Project)

Clostridioides (C.) difficile is an anaerobic pathogen, which occurs ubiquitously in the environment. Usually, it causes nosocomial enteritis, which can be associated with severe complications and a high rate of recurrence. Increasingly, however, C. difficile infections (CDI) are occurring without association to hospitals. Contaminated food has been implicated as a source of infection. Due to the...


Funding period: 2025 - 2025

Relevancy: 100%

Intestinal organoids as tools for the investigation of foodborne viruses (Project)

Efficient infection models are crucial for the investigation of the properties of food-borne viruses. They enable both, detailed investigation of applied aspects like virus stability and inactivation, as well as assessment of basic virus characteristics such as host specificity, under laboratory conditions. Classical laboratory-based infection models use established cell lines that are grown as...


Funding period: 2025 - 2025

Relevancy: 100%

Enhancing Food safety: An international approach to real-time foodborne pathogen data sharing (Project)

Detecting international foodborne outbreaks caused by plant-based raw materials remains a challenge for the relevant authorities. Simpler and more feasible strategies for sharing genome sequence data of foodborne pathogens isolated from imported food can significantly help to identify long-lasting international outbreaks more quickly. While clinical isolates are useful for identifying an...


Funding period: 2025 - 2025

Relevancy: 100%

Evaluation of a zebrafish larvae model to investigate the virulence of different Salmonella strains as an alternative to conventional animal experiments (Project)

This research project aims to establish an innovative zebrafish larvae model as an alternative method to conventional animal testing. The focus is on investigating the virulence of different Salmonella strains. This model is intended to complement and extend the Caenorhabditis elegans virulence assay already successfully implemented in FG42 and in Division Biological Safety of the BfR in order to...


Funding period: 2025 - 2025

Relevancy: 100%

Correlations of internal and external exposure for the use of epidemiological studies for risk assessment (Project)

In the scope of the EPIC-study there will be analysed blood samples with regard to arsenic in cooperation with the DKFZ Heidelberg. Therefore, data from EPIC-Heidelberg of 3.794 participants at the age of 35-65 years will be considered, that have been recruited between 1994-1998. The DKFZ will use the data for evaluating epidemiological questions in the context of the development of breast cancer...


Funding period: 2024 - 2025

Relevancy: 100%

Development of a human Multi-Organ-on-Chip System to investigate the function of monocytes and macrophages after ischemia-reperfusion damage (Project)

The project aims to develop a novel multi-organ-on-a-chip system based on human cell types that can recapitulate the infiltration of monocytes and macrophages into cardiac tissue after ischemia-reperfusion injury in vitro and thus replace animal models. The key aspects and related questions include: 1) The optimization of a MOoC prototype into a cardiac tissue model that better reflects the cell...


Funding period: 2024 - 2027