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Relevancy: 37%

Collaborative project: Mapping and exploitation of new sources of resistance to tan spot (Pyrenophora tritici-repentis) in wheat (Project)

...In the frame of this project, 8 PTR-isolates, which were collected in Germany and Hungary, were classified. Four out of these were classified as PTR race 8, which was the most frequent one. Based on phenotypic data estimated in three years field trials on 4 DH-populations and respective genetic maps (SSRs, DArTS, AFLPs), major QTL for resistance to P. tritici-repentis were identified on chromosomes 1A, 5B and 7B. ...


Funding period: 2006 - 2010

Relevancy: 37%

Collaborative project: Mapping and exploitation of new sources of resistance to tan spot (Pyrenophora tritici-repentis) in wheat - Subproject 2 (Project)

...In the frame of this project, 8 PTR-isolates, which were collected in Germany and Hungary, were classified. Four out of these were classified as PTR race 8, which was the most frequent one. Based on phenotypic data estimated in three years field trials on 4 DH-populations and respective genetic maps (SSRs, DArTS, AFLPs), major QTL for resistance to P. tritici-repentis were identified on chromosomes 1A, 5B and 7B. ...


Funding period: 2006 - 2010

Relevancy: 37%

MIRABEL - Integrated framework for risk and cost/benefit analysis of food allergens (Project)

...The survey will be designed and implemented by partners 1 (ANSES/DSA), 2 (Inra) and 3 (Allergo-Vigilance Network). ...Then, the model will be applied on the data collected during tasks 1 and 2 and will be used to assess the impact on the risk of different management options. This task is under the responsibility of partner 1. The task 4 consists of the cost-benefit analysis for the different stakeholders (food industry, allergic individuals and regulators). ...


Funding period: 2013 - 2013

Relevancy: 37%

Pilot Studies "Nutritional Epidemiology” and “Epidemiology of chronic diseases”, implemented within NFDI4Health (National research data infrastructure on personal health data) (Project)

...Pilot study 5.1.1: Systematic investigation of methodological limitations in the derivation of dietary patterns numerous exploratorily derived dietary patterns in last decades • no comprehensive investigation of methodological constraints, e.g.: • influence of different energy adjustment techniques • different levels of granularity for dietary data • no systematic investigation of simplified dietary patterns, e.g.: • different cut-offs for factor loadings on pattern composition Pilot study 5.1.2: Association of dietary sugar intake and body composition [among participants with genetic predisposition for a high sugar intake] • Association of added or free sugar intakes with development of overweight discussed for many years • European Food Safety Authority (EFSA): update on their "Tolerable upper intake level for dietary sugars“ -> not possible to set a recommendation due to major research gaps • Pooled analyses examining the impact of sugar intake on the development of obesity and non-communicable diseases are desired • Study on sugar intake (e.g. total, added and free sugars) + its main sources (e.g. SSB, juices, sweets) of children, adolescents and adults in Germany and its association with overweight • Biomarker data (e.g. urinary sugar excretion) and genetic factors (e.g. genetic preference for sweet foods) considered, if available...


Funding period: 2022 - 2023

Relevancy: 37%

Genomcs-driven analysis of the wheat/Fusarium pathosystem for healthy food and feed product development (Project)

...The aim of the project is the application of genome based and proteomic methods for (1) the selection for resistance against Fusarium (FHB) and for reduced mycotoxin production, (2) the analyses of the host-pathogen-interaction wheat/fusarium, (3) population and association genetics studies on Fusarium graminearum isolates. ...Studies conducted at the JKI aim at the construction of a high resolution mapping population for a FHB-QTL located on chromosome 2A of Triticum monococcum followed by marker saturation and the identification of candidate genes. ...In 2016 the high-resolution mapping population could be increased to 1991 F2-plants, providing a genetic resolution of 0.025 % recombination. 421 heterozygot recombinant plants and 16 homozygous recombinant plants could be identified for the first QTL-Intervall and 242 heterozygous recombinant plants and 7 homozygous recombinant plants could be selected for the second QTL-Interval. ...


Funding period: 2015 - 2018

Relevancy: 36%

Collaborative project: Research on basic principles for the production of breakfast cereals with reduced energy density enriched in dietary fibre and polyphenols - subproject 1 (Project)

...Frequent consumption of carbohydrate-rich food with a high glycemic index appears to increase the risk for obesity, type 2 diabetes, and other metabolic disorders and diseases, e.g. cardiovascular diseases and certain forms of cancers. ...The main aim of the joint project is to study the scientific background for the application of two novel food processing techniques: (1) high-temperature short-time extrusion (HTST) will be studied to design dietary fibre-rich breakfast cereals with reduced energy density, high contents of bioactive polyphenols and an optimised sensory quality (Work Packages; WPs2,3), (2) high-pressure high-temperature extraction (HPHT) will be investigated to extract dietary fibre and bioactive polyphenols from the by-product of chokeberry juice production (pomace) by using subcritical water, thus avoiding organic solvents (WP1). Furthermore, the optimised extruded products and extracts prepared by both processing methods will be analysed in detail for/used for: (a) changes in the molecular structures of dietary fibre components as influenced by HTST and HPHT processing (WP4), (b) nutritional quality aspects (e.g. contents of dietary fibre, sugars, and polyphenols) (WP1), (c) digestibility of carbohydrates and in vitro bioavailability of polyphenols (WP5), (d) in vivo tests (human intervention study) measuring blood glucose levels and the glycemic index after consumption of selected samples based on the results of the in vitro tests (WP5). ...


Funding period: 2016 - 2019

Relevancy: 36%

Application of naturally occurring antagonists of the cabbage white fly (Aleyrodes pro-letella) in organic brassica crops in combination with netting (Project)

...The cabbage whitefly, Aleyrodes proletella has developed to a key pest in brassica vegetables throughout Germany In a 3-year project we investigated the barrier effect of netting (0.8 x 0.8mm) in combination with the native parasitoid Encarsia tricolor and the predator Clitostethus arcuatus in an inundative approach in Brussels sprouts. ...Preponing the timing of the first release about 3 weeks to early July in 2009 resulted additionally in a significant reduction in pest density by 39% and a 23% increase of marketable yield. ...


Funding period: 2007 - 2010

Relevancy: 36%

Immunomodulatory effects of food ingredients (Project)

...Lipids in health and disease. 2016 Feb;15(21):1-12. Jaudszus A, Lorkowski S, Gruen M, Roth A, Jahreis G.: Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells. International journal of inflammation. 2014 Jun; 149628:1-6. Jaudszus A, Gruen M, Watzl B, Ness C, Roth A, Lochner A, Barz D, Gabriel H, Rothe M, Jahreis G.: Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. ...PlosOne. 2013 Jun; 8(6):1-5-e66690.  ...


Funding period: 2001 - 2016

Relevancy: 36%

Lameness prevalence and its risk factors in organic breeding sows kept in housing systems with run for animals (Project)

...Mean prevalence of lameness in pregnant sows was 6,9 % (0 – 34,8 %, Median 5,1 %) and thus substantially lower than data from conventional pig farming. ...Analysis of the total dat set (n=40 farms, 1,111 sows), but not considering the litter number, the factors claw length (higher risk with too long claws), self-assessment of lameness by the farmers (higher risk when deviating from the true prevalence), provision of access to an outdoor run for gilts (less lameness, when outdoor run available) and cleaning of the pens for pregnant sows (higher risk when cleaning takes place regularly) remained in the final model, besides swellings on the legs. ...


Funding period: 2012 - 2013

Relevancy: 36%

Molecularkinetic characterization of the transport and the distribution of the pro-carcinogene Benzo[a]pyrene in vitro and in vivo ? new kinetic data for risk assessment (Project)

...The interaction between the cytochrome P450-system, phase II xenobiotic-metabolizing en-zymes (XMEs) such as glutathione-S-transferases, UDP-glucuronosyl transferases and sul-fotransferases, and ABC-transport proteins is an important part of the mucosa of the small intestine acting as a potential biochemical barrier for nutritional- and eco-toxicological rele-vant compounds.Intestinal resorption of cancerogenic contaminants of food such as the polycyclic aromatic hydrocarbon (PAHs) benzo[a]pyrene (B[a]P) is affected by the interaction of CYP1A1/CYP1B1, phase II XMEs and ABC-transport proteins. It was shown that excretion of the B[a]P phase II metabolites including B[a]P-glucuronides and B[a]P-sulfates is medi-ated by breast cancer resistance protein (BCRP) (Ebert et al., 2005).In the project we here apply for the mechanism of detoxification of the ultimate carcino-genic phase I B[a]P metabolite anti-B[a]P-7,8-diol-9,10-epoxide (BPDE) will be studied. Formation of glutathione conjugates mediated by glutathione-S-transferases (GSTs) as well as the excretion of these conjugates will be analysed. ...Therefore, the double MRP2/3 knock out mouse will be employed to analyse the influence of MRP2 and MRP3 in the distribution of the metabolites of B[a]P....


Funding period: 2009 - 2009