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Imprint
Nutrition and intestinal microbiota
Project
Project code: MRI-PBE-08-47
Contract period: 01.01.2001
- 31.12.2017
Purpose of research: Applied research
The interactions between nutrition and intestinal mikrobiota are influencing the human organism in a multitude of ways (e.g. intestinal barrier function, energy metabolism). The research work regarding intestinal microbiota consider the physiological effects of microbial metabolites (e.g. short-chain fatty acids) of food constituents and endogenous microbial metabolites (e.g. antimicrobial peptides) as well as direct effects of intestinal bacteria in humans (e.g. immune system). The influence of nutrition on microbiota and their interactions with the host is being analyzed in vitro and in vivo (animal model, human). Detection methods regarding the physiological effect of intestinal microbiota as well as the characterization of mechanisms of action, that have a part in the prevention of nutrition-related diseases will be established. The research topic intestinal microbiota will be will be handled at the MRI across several departments. The collaboration of the MRI departments enables a characterization of intestinal microbioata as well as the food-associated microbiota and the identification of microbiota-generated metabolite patterns in the human metabolome (metabolomics).
Section overview
Subjects
- Physiology of Nutrition
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)
