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Imprint
Basic molecular principals of the effects of food on the gastrointestinal tract and the immune system
Project
Project code: MRI-PBE-08-006
Contract period: 01.01.2001
- 31.12.2016
Purpose of research: Basic research
Disclosure of probiotic mechanisms, e.g. effects on intestinal gene expression. Feeding germ-free rats the probiotic bacterium LGG for two weeks induced an upregulation of the genes for matrin 3, guanin-nucleotide-binding protein and for poly-ubiquitin in the mucosa of the small intestine, while genes for cytochrom-oxidase C and ferritin were downregulated. A context to established mechanisms of effecs of probiotic bacteria has not been found yet.
Section overview
Subjects
- Physiology of Nutrition
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)
