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Coordinated projects of "Federal Institute for Risk Assessment"

New strategies for the reduction of disease on organic broiler farms with special consideration of the gut microbiome

Project code: 2821OE035
Excutive institution: Federal Institute for Risk Assessment
Contract period: 2022 - 2025

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Determination and characterization of the relase of volatiles, particles and nanomaterials from filaments during 3D printing

Project code: BfR-CPS-08-1322-721
Excutive institution: Federal Institute for Risk Assessment
Contract period: 2019 - 2023

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Characterization and Quantification of human contact allergen-specific T cell populations in human blood and local skin enrichment

Project code: BfR-CPS-08-1322-718
Excutive institution: Federal Institute for Risk Assessment
Contract period: 2019 - 2023

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Investigating cross-reactivity of metal-specific T cell clones as molecular basis of co-sensitizations

Project code: BfR-CPS-08-1322-719
Excutive institution: Federal Institute for Risk Assessment
Contract period: 2019 - 2023

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Effective combination of Phages and Antibiotics for improved Therapy of Klebsiella pneumoniae

Project code: 01KI2302B,BfR-BIOS-23-60-0103-05.P254
Excutive institution: Federal Institute for Risk Assessment
Contract period: 2023 - 2026

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Coordinated projects of subordinate institutions of "Federal Institute for Risk Assessment"

siRNA technology in mammalian cells as alternative of knock-out mice: Functional investigations of proteins of the Myc-Miz-1-TopBP1-network (translation).

Project code: BfR-ZEBET-02-1328-172
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2003 - 2004

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Use of transgenic animals in biomedical research in Germany - survey 2001 to 2003 and perspectives to change research to non-animal test methods

Project code: BfR-ZEBET-02-1328-173
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2003 - 2004

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Construction and Prevalidation of V79 Pathway Cell Lines: Heterologous Co-Expression of human Cytochrom P450 1A2 and polymorphic forms of human N-Acetyltransferase in V79 Chinese Hamster Cells for in vitro-studies on toxicity and metabolism of chemicals and drugs.

Project code: BfR-ZEBET-08-1328-166
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2001 - 2004

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Improvement of an in vitro stem cell assay for developmental toxicity: Establishing molecular endpoints of tissue specific development

Project code: BfR-ZEBET-02-1334-142
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2000 - 2004

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Cell culture models of human nasal mucosa for in-vitro drug absorption studies (follow-up project to 1328-469)

Project code: BfR-ZEBET-08-1328-508
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2013 - 2014

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Database search for the development of a multiorgan chip as an alternative to animal experiments with repeated dose toxicity testing

Project code: BfR-ZEBET-08-1322-599
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2014 - 2014

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Generation of three dimensional vascular tissues and establishment of long-term cultures for establishing a multi-organ chip as an alternative to repeated dose (systemic) toxicity testing in vivo

Project code: BfR-ZEBET-08-1322-601
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2014 - 2014

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Actions of Botulinum Toxin A in nerve-muscle-tissue-cultures: A proof-of-principle-study

Project code: BfR-ZEBET-08-1328-456
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2010 - 2013

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Refinement methods to reduce laboratory animal suffering: A review of German biomedical and animal research applications from 2010 to identify how refinements are used in experiments involving rodents

Project code: BfR-ZEBET-08-1328-472
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2011 - 2014

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High-throughput methods for the estimation of toxicological effects of nanomaterials

Project code: BfR-ZEBET-08-1329-475
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2011 - 2015

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