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Lead in game meat after cooking treatment - bioavailability of the lead from ammunition - feeding study with pigs
Project
Project code: BfR-SiN-08-1322-598
Contract period: 01.03.2014
- 31.12.2017
Purpose of research: Applied research
Scientific studies on the quantitative description of the influence of different preparations/treatments of lead shot game meat on the solubility of the lead are scarce. This project aims to derive quantitative descriptions of the mere qualtitative statements by Hecht (1984) concerning this issue. This will contribute to optimise the risk assessment concerning the consumption of lead shot game meat in the sense of consumer protection and to derive recommendations for food prevention. The aim of the planned study is to determine the bioavailability of the lead found in game meat. The meals which have been prepared in a precursor project (with known lead content) will be fed to pigs. Pigs are well-known model organisms for human beings. In pre-determined time intervals blood will be taken from the pigs and the blood lead concentration will be determined. In the case of an increase in the blood lead concentration of the animals following a lead containing meal, the absorption of the lead from the meat eaten is assumed. The calculated absorption rates can be transferred to human beings and will be compared with already existing data for human beings. Furthermore, the iron content of the game meat and the pigs`blood will be determined. These data are required for the interpretation of the observed lead levels in the pigs blood because Fe deficiency leads to an increased lead resorption in the intestine. The obtained data will be used for biokinetic models.
Section overview
Subjects
- Wildlife Biology
- Nutritional behaviour
- Toxicology