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Metabolic effects of Endocrine Disrupting Chemicals: novel testing methods and adverse outcome pathways (EDCMET)
Project
Project code: BfR-LMS-08-1342-535
Contract period: 01.01.2019
- 31.12.2023
Budget: 5,980,409 Euro
Purpose of research: Applied research
The EDCMET project covers a wide variety of methodologies for novel and improved approaches to address the metabolic effects of EDs, ranging from in silico, to in vitro, in vivo, and ultimately, epidemiological data to associate the levels of chemicals to ED-related metabolic effects. BfR part of the project: BfR will be engaged in in vitro experimentation related to functional metabolic profiling of EDs and multi-omics analyses devoted to ED-related AOP refinement and development. BfR will also participate in the analyses of animal studies with selected EDs in order to elucidate in vivo effects and related AOPs. BfR will lead the EDCMET activities related to “dissemination and outreach”, including effective dissemination and stakeholder involvement, workshop organization, and communication of the project results to supranational bodies to foster future regulatory implementation of ED test systems.
Section overview
Subjects
- Biotechnology
