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Imprint
Molecular typing of Listeria monocytogenes in food as basis for an efficient risk assessment and control of listeriosis in Germany (MolTypList)
Project
Project code: BfR-BIOS-08-1339-100, GE20160326
Contract period: 01.01.2017
- 31.12.2018
Purpose of research: Experimental development
Listeriosis is a serious, partly life-threatening bacterial infectious disease. The comprehensive typing of Listeria monocytogenes (Lm) isolates from food and human and the use of standardized methods for whole genome sequencing play an important role for the control and reduction of human listeriosis, but that is currently missing in Germany. The aim of the present research project is to set up the whole genome sequencing for use in the surveillance of Lm in Germany and to generate representative typing data for isolates from food and food producing environments. The findings should give a better understanding about diversity, virulence, resistance and persistence of Lm isolates and allow tracing back human infections to outbreak sources (molecular mapping). The prospective use of whole genome sequencing in Listeriosis surveillance will facilitate the clarification of outbreaks and will contribute to the risk assessment of Lm.
Section overview
Subjects
- Biotechnology
- Food microbiology
- Toxicology
