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Influence various whole grain fractions on obesity
Project
Project code: MRI-PBE-08-1010 Vollkorn
Contract period: 01.08.2015
- 31.12.2020
Purpose of research: Experimental development
High consumption of whole grain products is associated with a reduced risk for various diseases. Most likely, indigestible carbohydrates (fibres) and secondary plant metabolites play an important role in mediating these effects, since they represent an important fraction of the whole grain. However, the exact mechanisms behind this interaction are still poorly understood. The aim of this research project is the evaluation of white flour, whole grain and selected grain fractions with respect to their potential to alleviate the development of adipositas. A special focus lies on the investigation of the intestinal microbiota and its contribution to metabolites.
Dötsch A, Loh G, Watzl B, Vatareck E, Stoll D, Huch M, Graf D. 2018, “influence of different whole grain fractions on the gut microbiota in DIO mice .“ Poster presentation at the DGE annual congress Hauser A, Eisenmann P, Muhle-Goll C, Luy B, Dotsch A, Graf D, Tzvetkova P (2019) Efficient Extraction from Mice Feces for NMR Metabolomics Measurements with Special Emphasis on SCFAs. Metabolites 9 (3). doi:10.3390/metabo9030055 Graf D, Weitkunat K, Dötsch A, Liebisch G, Döring M, Krüger R, Stoll, D, Vatareck E, von Coburg E, Loh G, Watzl B. (2019): Specific Wheat Fractions Influence Hepatic Fat Metabolism in Diet-Induced Obese Mice. Nutrients. 2019 Oct 2;11(10). pii: E2348. doi: 10.3390/nu11102348
Section overview
Subjects
- Physiology of Nutrition
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)
