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Imprint
Influence of dietary pulses on gut barrier function
Project
Project code: MRI-PBE-08-1010-hülsenfrüchte-darmbarriere
Contract period: 01.02.2017
- 31.12.2023
Purpose of research: Experimental development
Keywords: nutrition, nutrient, health promoting ingredients, pulses, pulse products
A impaired gut barrier function is associated with various diseases such as obesity-associated inflammation or inflammatory bowel diseases. Dietary pulses could influence gut barrier function, due to their nutrient composition (high content of fiber, phytochemicals and protein). Even though epidemiological studies suggest that pulse consumption is associated with beneficial health effects, the meachnisms of action remain unkown. The aim of this project is to investigate the impact of dietary pulses on gut barrier function. Therefore bioactive fractions as well as their meachnisms of action will be identified. Based on the results of this project innovative, health-promoting pulse products can be developed.
Graf D, Monk JM, Lepp D, Wu W, McGillis L, Roberton K, Brummer Y, Tosh SM, Power KA. (2019): Cooked Red Lentils Dose-Dependently Modulate the Colonic Microenvironment in Healthy C57Bl/6 Male Mice. Nutrients. 2019 Aug 9;11(8). pii: E1853. doi: 10.3390/nu11081853.
Graf D, Monk JM, Wu W, Wellings HR, Robinson LE, Power KA (2019): Red lentil supplementation reduces the severity of dextran sodium sulfate-induced colitis in C57BL/6 male mice. Journal of Functional Foods Volume 64, January 2020, 103625
Section overview
Subjects
- Physiology of Nutrition
Framework programme
Funding programme
Excutive institution
MRI - Department of Physiology and Biochemistry of Nutrition (MRI-PBE)
