We use cookies on our website. Some are necessary for the operation of the website. You can also allow cookies for statistical purposes. You can adjust the data protection settings or agree to all cookies directly.
Data Protection Declaration
Imprint
Studies on toxicity and genotoxicity of substances from commodities, e.g. azo dyes and vulcanisation aids
Project
Project code: BfR-PRS-02-1322-184
Contract period: 01.01.2002
- 31.12.2007
Purpose of research: Applied research
By using commodities consumers are frequently exposed to mixture of substances. The aim of the studies is to contribute to the question whether toxicological investigations of migrates are suitable. Initially, azo dyes in clothing are studied as model compounds.Cytotoxicity and mutagenicity of the azo dyes AR 1 and DO 3 were investigated. Results indicated clastogenic activity of AR 1 in the presence of a metabolising system. DO 3 exhibited potential for induction of gene mutation both in the absence and presence of a metabolising system. Further studies are needed including also exposure of consumers to assess human risk.
Section overview
Subjects
- Biotechnology
- Toxicology
