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Investigation of protease use against fish viruses in aquacultures (PRO-FI)

Project


Project code: 2815NA088
Contract period: 01.07.2016 - 31.12.2019
Budget: 153,630 Euro
Purpose of research: Applied research

Although aquacultures play a very important role for the supply with high-quality food nowadays, traditional fish farms still struggle with commercial viability. One of the relevant reasons for that are fish viruses such as, e.g. koi herpes virus (KHV), viral hemorrhagic septicemia virus (VHSV) or infectious hematopoietic necrosis virus (IHNV), that result in very high mortality rates and great losses in case of an outbreak. Unfortunately, there are still no uniform guidelines for disinfection measures after such outbreaks in Germany. In a recently completed co-operation project at the Institute of Bioprocess Engineering (“Measures against fish viroses in ecologic aquaculture”, FKZ 10OE053, BÖLN) it was shown for the first time that a common, commercially available protease can be successfully used for inactivation of KHV or VHSV. Nevertheless, the performed experiments still left a lot of unanswered questions. Thus, there is a great need for further research that can lead to establishing a very effective, environmentally friendly and cheap disinfection agent. Therefore, the applicability of various, commercially available, proteases for the disinfection of ponds after the outbreak of economically relevant viral diseases should be investigated in the project described here.

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