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RESET II - resistances in humans and animals
Contract period : - 2016
The research network RESET deals with the study of antibiotic resistance in a group of bacteria, the Enterobacteriaceae. These include inter alia Escherichia (E.) coli and Salmonella (S.) enterica, which occur not only in humans but also in animals and in the environment.
Coordinating institution
Institut für Biometrie, Epidemiologie und Informationsverarbeitung (IBEI)
Subprojects
Studies in animals, food and the environment (WP 2a)
- Collaborative project ESBL- and (fluoro-)quinolone resitance in enterobactericeae (RESET). Project IP1 characterization of newly emerging mechanisms for transfer of resistance to ß-lactam antibiotics with extended spectrum (ESBLs) and (fluoro) quinolones in German-Salmonella enterica and Escherichia coli isolates from healthy poultry and pigs and products thereof
- Coordinated project: ESBL and (fluoro)quinolone RESistance in EnTerobacteriaceae
- Collaborative Project RESET II: Epidemiological and statistical analysis, as well as environmental contamination and resistance development
- Collaborative Project RESET II: dissemination of ESBL / AmpC-producing enterobacteriaceae along the entire broiler chain: Vulnerability Analysis and determination of intervention points
- Collaborative Project RESET II: Genome-based epidemiology of ESBL, AmpC or carbapenemase-producing Gram-negative bacteria from human, veterinary and environmental samples
Studies in the human population (WP 2b)
Characterization of bacteria and resistance properties (WP 3)
- Characterization of emerging resistance mechanisms to β-lactam antibiotics (fluoro) quinolones in E. coli and S. enterica isolates from cattle and sick animals
- Resistance testing and molecular characterization of ESBL and (fluoro) quinolone resistance of E. coli and S. enterica from healthy pigs, poultry, food and the environment
- Collaborative Project RESET II: study to estimate the ESBL - prevalence, infection rates after colonization and population-specific risk factors for ESBL colonization and infection
- RESET-II: Network project 'ESBL and Fluorchinolon-Resistence in Enterobacteriaceae'. Subproject IP7
Pharmacological experiments (WP 4)
Risk assessment (WP 5)
