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Alternative ways for reducing Fusarium susceptibility in wheat leading to a lesser contimation with mycotoxins - a contribution to health care and consumer protection
Project
Project code: JKI-RS-08-2359
Contract period: 01.03.2005
- 31.03.2008
Purpose of research: Applied research
On Arabidopsis it was shown that the introgession of genetic information coding for a fusarium specific antibody and antifungal proteins leads to a significant increase in resistance to Fusarium in comparison to control plants and those only expressing the antibody or the antifungal protein (Peschen et al. 2004, Nature Biotechnology 22: 732-738). Therefore, this procedure, i.e. combining a specific antibody with antifungal proteins may be a strategy to reduce Fusarium also in wheat thereby contributing significantly to health care and consumer protection. Wheat plants containing genetic information for the specific antibody and respective antifungal proteins have been created by the Fraunhofer Institute for Molecular Biology and Applied Ecology, already. This project in a first step aims at proving whether this strategy is also efficient in monocotyledoneous species, i.e. wheat, by testing respective wheat plants with different Fusarium isolates in growth chambers. In this respect analyses will be carried out to determine whether the combination of different antifungal proteins will lead to a higher level of resistance. In parallel these genotypes will be analysed on the molecular level at the Fraunhofer institute. In case a significant reduction in susceptibility will be found, interaction with different pathogens will be determined.
Section overview
Subjects
- Genetic Resources
- Toxicology
Framework programme
Funding programme
Excutive institution
Institute of Resistance Research and Stress Tolerance (JKI-RS)