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Imprint
Identification of gut microbiota which confer resistance against Campylobacter infection
Project
Project code: BfR-BIOS-08-1329-497
Contract period: 01.10.2012
- 30.11.2013
Purpose of research: Applied research
Campylobacter is the most important food-poisoning bacterium in Europe. Many studies point to chicken meat as the prominent infection source. In addition, raw milk and contact with pets lead to a significant risk for infection with Campylobacter. Successful dissemination of Campylobacter is primarily based on the bacterium’s capability to efficiently colonize the intestine of many birds and mammals, including humans. The eradication of Campylobacter in these reservoirs is one of the key goals of current research.
There is only one infection model, in which it was unequivocally shown that an unknown bacterial population in the normal gut flora of mice is able to completely abolish colonization of C. jejuni (Bereswill et al., 2011). The goal of this project is to identify the bacterial species that confer colonization resistance against Campylobacter infection. Those bacteria will be further characterized with regard to their physiological potential to prevent colonisation and infection. Particularly with regard to increasing antibiotic resistances in Campylobacter observed in the framework of the zoono-sis monitoring by the BfR, alternative strategies for the eradication of Campylobacter infections are essential.
Section overview
Subjects
- Animal health
