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Information System for Agriculture and Food Research

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Lyssavirus Research Network

Collaborative Project


Contract period: 01.07.2010 - 30.06.2013
Coordinating institution: Friedrich-Loeffler-Institute - Federal Research Institute for Animal Health

The proposed project uses a hypothesis-driven approach focusing on lyssavirus dynamics and maintenance, virus evolution and diversity, as well as host biology, to afford a significant progress in neglected zoonotic disease prediction and intervention. Understanding natural reservoirs and sources of lyssaviruses as well as the mechanisms these viruses have developed to spill over into non-reservoir species including humans are essential for decision-making and preventive work in the public health sector. A concerted research effort is therefore necessary, using proven surveillance strategies, sophisticated and novel diagnostic methods as well as in-vitro and in-vivo disease models. Technology transfer to countries where rabies is endemic will help to improve surveillance, diagnosis and effective control measures in the global fight against rabies.

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Collaborative Projects

Potential public health hazard

Immune factors

Animal model

Partial / full sequencing

Reverse genetics in vitro

Technological platform

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