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Coordinated projects of "BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments"

Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals

Project code: BfR-ZEBET-08-1328-208
Contract period: 2007 - 2010
Funding institution: Federal Institute for Risk Assessment (BfR)

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Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro

Project code: BfR-ZEBET-08-1322-295
Contract period: 2004 - 2010
Funding institution: Federal Institute for Risk Assessment (BfR)

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Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances

Project code: BfR-ZEBET-08-1328-205
Contract period: 2007 - 2009
Funding institution: Federal Institute for Risk Assessment (BfR)

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Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures

Project code: BfR-ZEBET-08-1328-192
Contract period: 2006 - 2009
Funding institution: Federal Institute for Risk Assessment (BfR)

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Development of a novel approach in hazard and risk assessment of reproductive toxicity by a combination and application of in vitro, tissue and sensor technologies - ReProTect

Project code: BfR-ZEBET-08-1342-423
Contract period: 2004 - 2009
Funding institution: European Commission (EC)

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Refinement of the LCSA (loose-fit coculture-based sensitization assay)

Project code: BfR-ZEBET-08-1328-202
Contract period: 2007 - 2008
Funding institution: Federal Institute for Risk Assessment (BfR)

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Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets

Project code: BfR-ZEBET-08-1328-204
Contract period: 2007 - 2008
Funding institution: Federal Institute for Risk Assessment (BfR)

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Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies

Project code: BfR-ZEBET-08-1328-190
Contract period: 2005 - 2008
Funding institution: Federal Institute for Risk Assessment (BfR)

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Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays

Project code: BfR-ZEBET-08-1334-183
Contract period: 2009 - 2010
Funding institution: Federal Ministry of Education and Research (BMBF)

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Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials

Project code: BfR-ZEBET-08-1334-168
Contract period: 2004 - 2007
Funding institution: Federal Ministry of Education and Research (BMBF)

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