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Coordinated projects of "BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments"

Database search for the development of a multiorgan chip as an alternative to animal experiments with repeated dose toxicity testing

Project code: BfR-ZEBET-08-1322-599
Contract period: 2014 - 2014
Funding institution: Federal Institute for Risk Assessment (BfR)

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Generation of three dimensional vascular tissues and establishment of long-term cultures for establishing a multi-organ chip as an alternative to repeated dose (systemic) toxicity testing in vivo

Project code: BfR-ZEBET-08-1322-601
Contract period: 2014 - 2014
Funding institution: Federal Institute for Risk Assessment (BfR)

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Actions of Botulinum Toxin A in nerve-muscle-tissue-cultures: A proof-of-principle-study

Project code: BfR-ZEBET-08-1328-456
Contract period: 2010 - 2013
Funding institution: Federal Ministry of Food and Agriculture (BMEL)

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Refinement methods to reduce laboratory animal suffering: A review of German biomedical and animal research applications from 2010 to identify how refinements are used in experiments involving rodents

Project code: BfR-ZEBET-08-1328-472
Contract period: 2011 - 2014
Funding institution: Federal Institute for Risk Assessment (BfR)

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High-throughput methods for the estimation of toxicological effects of nanomaterials

Project code: BfR-ZEBET-08-1329-475
Contract period: 2011 - 2015
Funding institution: Federal Institute for Risk Assessment (BfR)

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Identification of electrophysiological endpoints in stem cell-based models for developmental neurotoxicity assays

Project code: BfR-ZEBET-08-1328-491
Contract period: 2012 - 2013
Funding institution: Federal Institute for Risk Assessment (BfR)

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Severity assessment from an animal's point of view

Project code: BfR-ZEBET-08-1350-021
Contract period: 2017 - 2019
Funding institution: German Research Foundation - Deutsche Forschungsgemeinschaft e.V. (DFG)

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Evaluation of optimal transport condition for the shipping of human organotypic corneal equivalents for in vitro drug absorption studies

Project code: BfR-ZEBET-08-1328-488
Contract period: 2011 - 2014
Funding institution: Federal Institute for Risk Assessment (BfR)

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Porcine Lungs from the Slaughtering Process as a Model for Ex Vivo Lung Perfusion (EVLP)

Project code: BfR-ZEBET-08-1328-563
Contract period: 2018 - 2019
Funding institution: Federal Ministry of Food and Agriculture (BMEL) , Federal Institute for Risk Assessment (BfR)

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Establishment of a stem cell-based system for the systematic testing of negative side-effects of drugs on human cardiomyocytes

Project code: BfR-ZEBET-08-1329-471
Contract period: 2011 - 2014
Funding institution: Federal Institute for Risk Assessment (BfR)

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