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Identification of proteomic biomarkers in human after exposure to furan fatty acids (Project)

Furan fatty acids (FFA) are oxidation products of unsaturated fatty acids and result from thermal treatment of food containing fatty acids. Beside FFAs are found naturally in fish oil and plants. There’s a lack of data concerning the effects of furan fatty acids in human. Our recent in vitro studies had indicated genetic toxicity and cytotoxic activity. It is planned to show genetic toxicity and...


Funding period: 2006 - 2007

Relevancy: 100%

Investigations of food (milk) for Listeria spp (Project)

keine Angaben


Funding period: 2006 - 2006

Relevancy: 100%

Studies on the growth kinetics of Vibrio spp. in different matrices (Project)

no details


Funding period: 2006 - 2007

Relevancy: 100%

Investigation of Shiga-toxin 2e (Stx2e) producing strains of Escherichia coli as potential human pathogenic bacteria and their significance as contaminants in the food chain (Project)

A statistically relevant number of Shiga toxin 2e producing strains of Escherichia coli from different sources (human, animal, food, environment) shall be investigated for their virulence properties. The profound characterization of this set of bacteria shall contribute to assess their significance as agents of human disease.


Funding period: 2006 - 2007

Relevancy: 100%

Identification and prevalidation of hepatocellular biomarkers for detection and prediction of carci-nogenic effects of chemicals (part 1) (Project)

Assessment of the health risk posed by chemicals is based on exposure analysis and on the performance and evaluation of toxicity testing in animals. However, this traditional approach of toxicity testing involves a number of problems. In particular, long-term testing to detect carcinogenic effects is rather time-consuming and raises ethical problems. Unless mechanistic data are established...


Funding period: 2001 - 2004

Relevancy: 100%

Genotoxicity of flavouring substances (Project)

Sometimes there are no or only a few genotoxicity data available for food components. Especially in cases in which there is no basis to request data by law, the project is intended for contributing genotoxicity data. In vitro tests are used according to OECD guidelines.


Funding period: 2002 - 2006

Relevancy: 100%

Development of sample clean-up procedures preparing GC-C-IRMS measuremens of residues and contaminants in food (Project)

The measurement of stabile isotope ratios of carbon and oxygen by means of GC-C-IRMS (Gas Chromatographie-Combustion-Isotope Ratio Mass Spectrometry) demands a thoroughly developed sample clean-up leading to a baseline separation of the analytes of interest from matrix compounds during gaschromatography. Due to the low concentrations of residues and contaminants in food this is a not only a...


Funding period: 2002 - 2007

Relevancy: 100%

Optimization and validation of a highly sensitive and specific immunoassay for detection of cns-contamination in food (project within the framework of the Bavarian BSE research programme)/Development of a highly sensitive immunoassay for detection of CNS (Project)

TSEs are believed to be epidemiologically transmitted by the enteral intake of prion containing tissue of infected animals. Of particular concern are brain tissue, spinal cord and lymphatic organ tissues. The project is focused on the development of an easy-to-handle immunoassay for the detection of these particular tissues.


Funding period: 2002 - 2007