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Projects on "6.7 Development and validation of alternative methods to animal testing"

Development and validation of molecular toxicological test methods for chemical safety: design and establishment of new in vitro and non-vertebrate testassays

Project code: BfR-TOX-08-9-003
Excutive institution: BfR - Department 9: Experimental Toxicology and ZEBET
Contract period: 2015 - 2019

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Development of a biotransformation system for the metabolic activation of validated in vitro systems to study embryotoxicity

Project code: BfR-ZEBET-08-1334-192
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2008 - 2011

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Development of a single cell model of adult cardiomyocytes as a replacement method of animal experiments? Optical measurements of excitation-contraction coupling under the influence of test substances

Project code: BfR-ZEBET-08-1328-205
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2007 - 2009

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Development of bioreactors for in vitro testing of biological heart valves for reduction of animal experiments

Project code: BfR-ZEBET-08-1328-183
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2006

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Development of methods for detection of obesogenic substances

Project code: BfR-ZEBET-08-1322-707
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2017 - 2018

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Development of Predictive In Vitro Test for Developmental Neurotoxicity testing

Project code: BfR-ZEBET-08-1334-176
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2007 - 2011

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Embryonic stem cell-based novel alternative testing strategies (ESNATS)

Project code: BfR-ZEBET-08-1342-465
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2008 - 2013

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Equine precision cut lung slices as an in vitro model of obstructive airway diseases for the identification and characterization of drug targets

Project code: BfR-ZEBET-08-1328-204
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2007 - 2008

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Establishment of a stem cell-based system for the systematic testing of negative side-effects of drugs on human cardiomyocytes

Project code: BfR-ZEBET-08-1329-471
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2011 - 2014

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Establishment of normal human neural progenitor cells as an in vitro screening model for the evaluation of the neurotoxic potential of chemicals

Project code: BfR-ZEBET-08-1328-208
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2007 - 2010

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